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Using the case of failed vaccine trials in Hohoe, Ghana, we explore this milieu of trust by employing the concept of tandems of trust and control, with a particular focus on the perceived characteristics of the disease and the linkages formed. An analysis of qualitative interviews collected in Hohoe following the West Africa Ebola outbreak of 2014\u20132016 shows that the trust\/control nexus in vaccine trials precedes the implementation of those trials, while both the characteristics of Ebola and the political context shaped the formation and breakdown of relationships in the trial network.<\/jats:p>","DOI":"10.1017\/pls.2020.1","type":"journal-article","created":{"date-parts":[[2020,4,16]],"date-time":"2020-04-16T14:09:21Z","timestamp":1587046161000},"page":"38-55","source":"Crossref","is-referenced-by-count":8,"title":["Politics and trust in Ebola vaccine trials"],"prefix":"10.1017","volume":"39","author":[{"given":"John K.","family":"Aggrey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wesley","family":"Shrum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2020,4,16]]},"reference":[{"key":"S0730938420000015_r27","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-016-3799-x"},{"key":"S0730938420000015_r30","doi-asserted-by":"publisher","DOI":"10.1177\/0162243914554838"},{"key":"S0730938420000015_r25","doi-asserted-by":"publisher","DOI":"10.1017\/S0730938400014258"},{"key":"S0730938420000015_r22","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2005.11.026"},{"key":"S0730938420000015_r20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012223"},{"key":"S0730938420000015_r15","doi-asserted-by":"publisher","DOI":"10.3310\/hta11480"},{"key":"S0730938420000015_r14","doi-asserted-by":"publisher","DOI":"10.1177\/0038038505050536"},{"key":"S0730938420000015_r10","unstructured":"Boadu, K. 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