{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:39:51Z","timestamp":1760132391859},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"unspecified","delay-in-days":6421,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta genet. med. gemellol.: twin res."],"published-print":{"date-parts":[[1997,1]]},"abstract":"<jats:p><jats:bold>Objective<\/jats:bold>. To determine the correlation between quantitative measurements of antepartum uterine activity and cervical change twin gestations.<\/jats:p><jats:p><jats:bold>Methods<\/jats:bold>. Forty women from our Twin Clinic constituted the study group. Participants had a cervical examination each week between 20 and 37 weeks gestation and a cervical score (CS) was calculated as follows: CS = cervical length (cms)-cervical dilation (cms) at the internal os. The women also performed blinded home uterine activity monitoring (HUAM) for a mean of 7.0+3.0 hrs\/wk (+SD). Uterine activity was expressed as mean number of contractions\/hour\/week gestation based on the average of three independent reviewers. CS was determined by a single clinician unaware of the HUAM recordings. A significant change in the CS was defined as a reduction of at least 0.5 from the preceding week. Correlation coefficients were used to determine the association between uterine activity and change in the cervical score.<\/jats:p><jats:p><jats:bold>Results<\/jats:bold>. Twin pregnancy was characterized by a rise from 0.2 + .03 contractions\/hr at 20 weeks to 3.2 + 2.4 contractions\/hr at 37 weeks gestation. CS fell from a mean of 2.6 + 0.2 at 20 weeks to \u22122.1 + 0.9 at 37 weeks gestation. There was a significant negative correlation (\u22120.317, p&lt;.0001) between increasing uterine activity and decreasing CS. There were significantly more (p &lt;.002) contractions during the 7 days preceding a significant reduction in CS (3.3 + 3.5 contractions\/hr) than when the CS was unchanged (1.6\u00b11.5 contractions\/hr).<\/jats:p><jats:p><jats:bold>Conclusions<\/jats:bold>. In twin gestations, an increasing frequency of uterine contractions is strongly correlated with quantifiable cervical change between 20-37 weeks gestation. Persistent daytime contraction frequencies of &gt;3\/hr represent a risk factor for cervical dilation and\/or effacement.<\/jats:p>","DOI":"10.1017\/s0001566000000702","type":"journal-article","created":{"date-parts":[[2016,7,27]],"date-time":"2016-07-27T06:04:03Z","timestamp":1469599443000},"page":"1-7","source":"Crossref","is-referenced-by-count":4,"title":["Correlation of Antepartum Uterine Activity and Cervical Change in Twin Gestation"],"prefix":"10.1017","volume":"46","author":[{"given":"R. B.","family":"Newman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M.","family":"Ellings","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. M.","family":"O'Reilly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. C.","family":"Brost","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"III","given":"M. C.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"D.","family":"Gates","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,8,1]]},"reference":[{"key":"S0001566000000702_ref014","first-page":"695","article-title":"The influence of fetal number on antepar-tum uterine activity","volume":"73","author":"Newman","year":"1989","journal-title":"Obstet Gynecol"},{"key":"S0001566000000702_ref018","first-page":"157","volume-title":"Dilation of the Uterine Cervix. Connective Tissue, Biology and Clinical Management","author":"Steinetz","year":"1980"},{"key":"S0001566000000702_ref005","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1982.tb03611.x"},{"key":"S0001566000000702_ref013","first-page":"719","article-title":"Preterm labor in twin pregnancies: Prediction by cervical assessment","volume":"72","author":"Neilson","year":"1988","journal-title":"Obstet Gynecol"},{"key":"S0001566000000702_ref004","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(86)90383-2"},{"key":"S0001566000000702_ref006","first-page":"216","article-title":"Biology and biochemistry of myometrial contractility and cervical maturation","volume":"5","author":"Huszar","year":"1981","journal-title":"Semin Perinat"},{"key":"S0001566000000702_ref019","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(81)92100-0"},{"key":"S0001566000000702_ref008","first-page":"24S","article-title":"Preventing preterm birth in twin gestation. Home uterine activity monitoring and perinatal nursing support","volume":"76","author":"Knupple","year":"1990","journal-title":"Obstet Gynecol"},{"key":"S0001566000000702_ref009","first-page":"261","article-title":"Ripening of the cervix","volume":"2","author":"Liggins","year":"1978","journal-title":"Semin Perinat"},{"key":"S0001566000000702_ref016","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(91)90077-5"},{"key":"S0001566000000702_ref001","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(91)90510-X"},{"key":"S0001566000000702_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(93)90379-W"},{"key":"S0001566000000702_ref010","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-199404000-00006"},{"key":"S0001566000000702_ref012","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(91)90429-U"},{"key":"S0001566000000702_ref015","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(86)90596-X"},{"key":"S0001566000000702_ref011","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(87)90046-9"},{"key":"S0001566000000702_ref002","first-page":"56S","article-title":"Uterine activity characteristics in multiple gestations","volume":"76","author":"Garite","year":"1990","journal-title":"Obstet Gynecol"},{"key":"S0001566000000702_ref007","first-page":"273","article-title":"Initial evaluation of an ambulatory system for home monitoring and the transmission of uterine activity data","volume":"66","author":"Katz","year":"1985","journal-title":"Obstet Gynecol"},{"key":"S0001566000000702_ref017","first-page":"67S","article-title":"Ambulatory tocodynamometry data interpretation: Evaluating variability and reliability","volume":"76","author":"Scheerer","year":"1990","journal-title":"Obstet Gynecol"}],"container-title":["Acta geneticae medicae et gemellologiae: twin research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0001566000000702","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,12]],"date-time":"2019-05-12T15:25:23Z","timestamp":1557674723000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0001566000000702\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,1]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1997,1]]}},"alternative-id":["S0001566000000702"],"URL":"https:\/\/doi.org\/10.1017\/s0001566000000702","relation":{},"ISSN":["0001-5660","2059-6324"],"issn-type":[{"value":"0001-5660","type":"print"},{"value":"2059-6324","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,1]]}}}