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No sibship was found with two or more equally affected singleton members. One case of concordance among twins is referred. There were no parity, inbreeding, race and sex effects. Both hands and both feet were also equally affected. Precocious mortality and twinning were significantly higher among affected individuals. The presence of cleft lip and palate in one of our index patients may also reflect an etiological relationship. Among the sibs, the total incidence of congenital malformations was similar to that generally accepted for general populations.<\/jats:p>","DOI":"10.1017\/s0001566000009922","type":"journal-article","created":{"date-parts":[[2016,7,27]],"date-time":"2016-07-27T09:54:44Z","timestamp":1469613284000},"page":"133-140","source":"Crossref","is-referenced-by-count":4,"title":["Reduction Deformities, Twinning and Mortality in Brazilian Whites and Negroes"],"prefix":"10.1017","volume":"26","author":[{"given":"N.","family":"Freire-Maia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.B.C.","family":"Azevedo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,8,1]]},"reference":[{"key":"S0001566000009922_ref021","first-page":"137","volume-title":"An. Prim. Reun. Brasil. Gen\u00e9t. 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M.D. thesis, University of Campinas, Brazil."},{"key":"S0001566000009922_ref008","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1975.tb00304.x"},{"key":"S0001566000009922_ref005","volume-title":"Opera ex Domo Biolologiae Hereditariae Humanae Universitatis Hafniensis","volume":"19","author":"Birch-Jensen","year":"1949"},{"key":"S0001566000009922_ref015","first-page":"7","article-title":"Congenital skeletal limb deficiencies. A general view","author":"Freire-Maia","year":"1969","journal-title":"Birth Defect., Orig. Artic. Ser."},{"key":"S0001566000009922_ref010","doi-asserted-by":"publisher","DOI":"10.1159\/000151801"},{"key":"S0001566000009922_ref009","first-page":"266","volume-title":"Atas Prim. Sim. Sul-Americ. 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Cited by Salzano and Freire-Maia 1970."}],"container-title":["Acta geneticae medicae et gemellologiae"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0001566000009922","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T19:12:32Z","timestamp":1559070752000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0001566000009922\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,4]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1977,4]]}},"alternative-id":["S0001566000009922"],"URL":"https:\/\/doi.org\/10.1017\/s0001566000009922","relation":{},"ISSN":["1120-9623","2059-6316"],"issn-type":[{"type":"print","value":"1120-9623"},{"type":"electronic","value":"2059-6316"}],"subject":[],"published":{"date-parts":[[1977,4]]}}}