{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T12:03:07Z","timestamp":1780142587853,"version":"3.54.0"},"reference-count":53,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2009,2,12]],"date-time":"2009-02-12T00:00:00Z","timestamp":1234396800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[2009,8,28]]},"abstract":"<jats:p>Beneficial effects of <jats:italic>n<\/jats:italic>-3 fatty acids on a variety of physiological functions have been reported, but information related to the effects of oily fish consumed within a varied diet on glucose metabolism and diabetes risk is scarce. The objective of the study was to compare the effects of a diet rich in oily fish to those of a diet rich in red meat on lipid profile, oxidative status, glucose metabolism and insulin sensitivity in young, iron-deficient women. The study was designed attending the CONSORT statement guidelines. It was a randomised crossover dietary intervention study with two 8-week periods. Two diets were designed differing only in their oily fish or red meat content (four portions per week). Twenty-five young iron-deficient women with normal lipid, glucose and insulin levels participated in the assay. Lipid profile (total, LDL- and HDL-cholesterol, TAG), fasting glucose, fasting insulin, and oxidation (lipoperoxides) and inflammation (soluble intercellular adhesion molecule-1 and soluble vascular cell adhesion molecule-1) biomarkers were analysed. Insulin sensitivity was assessed by the Homeostasis Model Assessment (HOMA) and Quantitative Insulin Sensitivity Check Index (QUICKI). Insulin levels significantly decreased and insulin sensitivity significantly increased with the oily fish diet. HDL-cholesterol significantly increased with the oily fish diet. Other parameters did not significantly differ between diets. An increase in oily fish consumption increases insulin sensitivity in young iron-deficient women. This outcome should be considered when giving dietary advice to this population.<\/jats:p>","DOI":"10.1017\/s0007114509220794","type":"journal-article","created":{"date-parts":[[2009,8,6]],"date-time":"2009-08-06T11:59:24Z","timestamp":1249559964000},"page":"546-553","source":"Crossref","is-referenced-by-count":42,"title":["An oily fish diet increases insulin sensitivity compared to a red meat diet in young iron-deficient women"],"prefix":"10.1017","volume":"102","author":[{"given":"Santiago","family":"Navas-Carretero","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana M.","family":"P\u00e9rez-Granados","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"Schoppen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Pilar","family":"Vaquero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2009,2,12]]},"reference":[{"key":"S0007114509220794_manual_ref-42","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2007.01.010"},{"key":"S0007114509220794_manual_ref-10","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/70.5.817"},{"key":"S0007114509220794_manual_ref-36","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.jnutbio.2006.01.001","article-title":"Effects of dietary factors on oxidation of low-density lipoprotein particles","volume":"17","author":"Lapointe","year":"2006","journal-title":"J Nutr Biochem"},{"key":"S0007114509220794_manual_ref-50","doi-asserted-by":"publisher","DOI":"10.1007\/BF00400468"},{"key":"S0007114509220794_manual_ref-51","doi-asserted-by":"publisher","DOI":"10.2337\/diab.40.2.280"},{"key":"S0007114509220794_manual_ref-3","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.581355"},{"key":"S0007114509220794_manual_ref-13","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/55.5.1018"},{"key":"S0007114509220794_manual_ref-6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12468-3"},{"key":"S0007114509220794_manual_ref-23","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/18.6.499"},{"key":"S0007114509220794_manual_ref-22","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)04337-3"},{"key":"S0007114509220794_manual_ref-28","volume-title":"Unsaturated Fatty Acids: Nutritional and Physiological Significance: The Report of the British Nutrition Foundation's Task Force","year":"1992"},{"key":"S0007114509220794_manual_ref-9","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/65.5.1645S"},{"key":"S0007114509220794_manual_ref-45","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/84.6.1290"},{"key":"S0007114509220794_manual_ref-26","unstructured":"26 Instituto Nacional de Estad\u00edstica (INE) (2007) Encuestas de presupuestos familiares. http:\/\/www.ine.es\/inebmenu\/indice.htm (accessed May 2007)."},{"key":"S0007114509220794_manual_ref-27","first-page":"183","volume-title":"Gu\u00edas alimentarias para la poblaci\u00f3n espa\u00f1ola","author":"Aranceta","year":"2001"},{"key":"S0007114509220794_manual_ref-1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2007.01.013"},{"key":"S0007114509220794_manual_ref-35","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1601602"},{"key":"S0007114509220794_manual_ref-19","doi-asserted-by":"publisher","DOI":"10.1007\/s001250051499"},{"key":"S0007114509220794_manual_ref-41","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/134.5.1058"},{"key":"S0007114509220794_manual_ref-32","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/77.4.783"},{"key":"S0007114509220794_manual_ref-39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2004.09.006"},{"key":"S0007114509220794_manual_ref-17","doi-asserted-by":"publisher","DOI":"10.1051\/rnd:2004033"},{"key":"S0007114509220794_manual_ref-30","volume-title":"Fats and Oils in Human Nutrition. Report of a Joint FAO\/WHO Expert Consultation. FAO Food and Nutrition Paper no. 57","year":"1998"},{"key":"S0007114509220794_manual_ref-43","article-title":"n-3 Fatty acids in glucose metabolism and insulin sensitivity","volume":"24","author":"Mart\u00edn de Santa Olalla","year":"2009","journal-title":"Nutr Hosp"},{"key":"S0007114509220794_manual_ref-44","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1111\/j.1463-1326.2006.00576.x","article-title":"The impact of long chain n-3 polyunsaturated fatty acid supplementation on inflammation, insulin sensitivity and CVD risk in a group of overweight women with an inflammatory phenotype","volume":"9","author":"Browning","year":"2007","journal-title":"Diabetes Obes Metab"},{"key":"S0007114509220794_manual_ref-15","doi-asserted-by":"publisher","DOI":"10.2337\/diab.38.10.1314"},{"key":"S0007114509220794_manual_ref-20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2002.tb04290.x"},{"key":"S0007114509220794_manual_ref-8","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00548-3"},{"key":"S0007114509220794_manual_ref-38","doi-asserted-by":"publisher","DOI":"10.1007\/s003940170016"},{"key":"S0007114509220794_manual_ref-46","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-277X.2008.00902.x"},{"key":"S0007114509220794_manual_ref-48","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M009817200"},{"key":"S0007114509220794_manual_ref-37","doi-asserted-by":"publisher","DOI":"10.1079\/BJN2000220"},{"key":"S0007114509220794_manual_ref-33","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000038493.65177.94"},{"key":"S0007114509220794_manual_ref-12","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-5491.2002.00745.x"},{"key":"S0007114509220794_manual_ref-53","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.drudis.2008.01.006","article-title":"From a glucocentric to a lipocentric approach towards metabolic syndrome","volume":"13","author":"Mittra","year":"2008","journal-title":"Drug Discov Today"},{"key":"S0007114509220794_manual_ref-5","doi-asserted-by":"crossref","first-page":"1505S","DOI":"10.1093\/ajcn\/83.6.1505S","article-title":"n-3 Polyunsaturated fatty acids, inflammation, and inflammatory diseases","volume":"83","author":"Calder","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"S0007114509220794_manual_ref-11","doi-asserted-by":"publisher","DOI":"10.1097\/01.mol.0000236363.63840.16"},{"key":"S0007114509220794_manual_ref-14","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a117257"},{"key":"S0007114509220794_manual_ref-52","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/78.3.508S"},{"key":"S0007114509220794_manual_ref-21","doi-asserted-by":"publisher","DOI":"10.1079\/BJN2001421"},{"key":"S0007114509220794_manual_ref-25","first-page":"148","volume-title":"Bioavailability 2006. Optimizing Dietary Strategies for Better Health in Developing Countries","author":"Navas-Carretero","year":"2006"},{"key":"S0007114509220794_manual_ref-18","first-page":"353","article-title":"Effects of fish oil on metabolic responses to oral fructose and glucose loads in healthy humans","volume":"270","author":"Delarue","year":"1996","journal-title":"Am J Physiol"},{"key":"S0007114509220794_manual_ref-7","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200208000-00010"},{"key":"S0007114509220794_manual_ref-16","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1007\/s001250051620","article-title":"Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: the KANWU study","volume":"44","author":"Vessby","year":"2001","journal-title":"Diabetologia"},{"key":"S0007114509220794_manual_ref-29","unstructured":"29 Department of Health and Human Service, US Food and Drug Administration (2007) Substances affirmed as generally recognized as safe: menhaden oil. Federal Register, June 5, 1997. 62, 108: 30751\u2013757. http:\/\/frwebgate.access.gpo.gov\/cgi-bin\/getdoc.cgi?dbname\u00a0=\u00a01997_register&docid\u00a0=\u00a0fr05jn97-5 (accessed May 2007)."},{"key":"S0007114509220794_manual_ref-40","doi-asserted-by":"publisher","DOI":"10.1042\/cs1000091"},{"key":"S0007114509220794_manual_ref-47","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-008-1035-7"},{"key":"S0007114509220794_manual_ref-2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2004.05.043"},{"key":"S0007114509220794_manual_ref-34","doi-asserted-by":"publisher","DOI":"10.1177\/014107688808100902"},{"key":"S0007114509220794_manual_ref-4","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1194\/jlr.M500033-JLR200","article-title":"Docosahexaenoic acid changes lipid composition and interleukin-2 receptor signaling in membrane rafts","volume":"46","author":"Li","year":"2005","journal-title":"J Lipid Res"},{"key":"S0007114509220794_manual_ref-31","first-page":"413","volume-title":"Gu\u00edas alimentarias para la poblaci\u00f3n espa\u00f1ola","author":"Ros","year":"2001"},{"key":"S0007114509220794_manual_ref-24","doi-asserted-by":"publisher","DOI":"10.1080\/07315724.2008.10719680"},{"key":"S0007114509220794_manual_ref-49","doi-asserted-by":"publisher","DOI":"10.1080\/07315724.2007.10719633"}],"container-title":["British Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007114509220794","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T21:10:21Z","timestamp":1750453821000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007114509220794\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2,12]]},"references-count":53,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,12,14]]}},"alternative-id":["S0007114509220794"],"URL":"https:\/\/doi.org\/10.1017\/s0007114509220794","relation":{},"ISSN":["0007-1145","1475-2662"],"issn-type":[{"value":"0007-1145","type":"print"},{"value":"1475-2662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,2,12]]}}}