{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T21:50:50Z","timestamp":1793224250838,"version":"4.5.0"},"reference-count":29,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[2010,7,28]]},"abstract":"<jats:p>Due to little outdoor activity and low dietary intake of vitamin D (VD), Bangladeshi low-income women are at risk for osteoporosis at an early age. The present study assessed the effect of VD, Ca and multiple micronutrient supplementation on VD and bone status in Bangladeshi young female garment factory workers. This placebo-controlled 1-year intervention randomly assigned 200 apparently healthy subjects (aged 16\u201336 years) to four groups: VD group, daily 10\u00a0\u03bcg VD; VD and Ca (VD-Ca) group, daily 10\u00a0\u03bcg VD+600\u00a0mg Ca; multiple micronutrient and Ca (MMN-Ca) group, 10\u00a0\u03bcg VD and other micronutrients+600\u00a0mg Ca; a placebo group. Serum 25-hydroxyvitamin D (S-25OHD), intact parathyroid hormone (S-iPTH), Ca, phosphate and alkaline phosphatase were measured. Bone mineral density and bone mineral content were measured by dual-energy X-ray absorptiometry. All measurements were made at baseline and at 12 months. Significantly (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00\u00b7001) higher S-25OHD concentrations were observed in the supplemented groups than in the placebo group after the intervention. Supplementation had an effect (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00\u00b7001) on S-iPTH in the VD-Ca and MMN-Ca groups compared with the placebo group. Bone mineral augmentation increased at the femur in the supplemented groups. Supplementation with VD-Ca should be recommended as a strategic option to reduce the risk of osteomalacia and osteoporosis in these subjects. MMN-Ca may have analogous positive health implications with additional non-skeletal benefits.<\/jats:p>","DOI":"10.1017\/s0007114510000437","type":"journal-article","created":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T13:12:57Z","timestamp":1267449177000},"page":"241-247","source":"Crossref","is-referenced-by-count":46,"title":["Effect of vitamin D, calcium and multiple micronutrient supplementation on vitamin D and bone status in Bangladeshi premenopausal garment factory workers with hypovitaminosis D: a double-blinded, randomised, placebo-controlled 1-year intervention"],"prefix":"10.1017","volume":"104","author":[{"given":"Md Zahirul","family":"Islam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abu Ahmed","family":"Shamim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heli T.","family":"Viljakainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Akhtaruzzaman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atia H.","family":"Jehan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Habib Ullah","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferdaus Ahmad","family":"Al-Arif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christel","family":"Lamberg-Allardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2010,3,1]]},"reference":[{"key":"S0007114510000437_ref16","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.060302"},{"key":"S0007114510000437_ref20","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/69.5.842"},{"key":"S0007114510000437_ref5","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/81.5.1060"},{"key":"S0007114510000437_ref17","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1602374"},{"key":"S0007114510000437_ref1","first-page":"178","article-title":"Epidemiology of osteoporosis and osteoporotic fractures","volume":"7","author":"Cooper","year":"1992","journal-title":"Epidemiol Rev"},{"key":"S0007114510000437_ref24","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1602963"},{"key":"S0007114510000437_ref2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199709043371009"},{"key":"S0007114510000437_ref27","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.10331"},{"key":"S0007114510000437_ref15","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/81.1.175"},{"key":"S0007114510000437_ref13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1997.tb03094.x"},{"key":"S0007114510000437_ref26","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2001.16.8.1408"},{"key":"S0007114510000437_ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2004.03.040"},{"key":"S0007114510000437_ref9","unstructured":"9 Jahan K & Hossain M (1998) Nature and extent of malnutrition in Bangladesh. Bangladesh National Nutrition Survey 1995\u20131996, Dhaka, Bangladesh. Institute of Nutrition and Food Science, University of Dhaka."},{"key":"S0007114510000437_ref6","first-page":"81","article-title":"Hypovitaminosis D is common in both veiled and nonveiled Bangladeshi women","volume":"15","author":"Islam","year":"2006","journal-title":"Asia Pac J Clin Nutr"},{"key":"S0007114510000437_ref28","doi-asserted-by":"publisher","DOI":"10.1007\/s001980050030"},{"key":"S0007114510000437_ref25","doi-asserted-by":"publisher","DOI":"10.1007\/s001980070052"},{"key":"S0007114510000437_ref4","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1601284"},{"key":"S0007114510000437_ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-007-0459-0"},{"key":"S0007114510000437_ref18","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-1466"},{"key":"S0007114510000437_ref8","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114508894445"},{"key":"S0007114510000437_ref10","volume-title":"Vitamin D, Iron, Calcium and Overall Nutritional Status in Premenopausal Women in Two Regions of Bangladesh","author":"Islam","year":"2000"},{"key":"S0007114510000437_ref11","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1601597"},{"key":"S0007114510000437_ref12","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-67-4-644"},{"key":"S0007114510000437_ref3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199803123381107"},{"key":"S0007114510000437_ref14","first-page":"4125","article-title":"Vitamin D insufficiency and hyperparathyroidism in a low income, multiracial, elderly population","volume":"85","author":"Harris","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"S0007114510000437_ref19","volume-title":"The Asia Pacific Perspective \u2013 Redefining Obesity and its Treatment","year":"2000"},{"key":"S0007114510000437_ref22","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/77.5.1324"},{"key":"S0007114510000437_ref23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.2006.tb00226.x"},{"key":"S0007114510000437_ref29","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-005-1867-7"}],"container-title":["British Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007114510000437","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,28]],"date-time":"2019-04-28T19:15:29Z","timestamp":1556478929000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007114510000437\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3,1]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,7,28]]}},"alternative-id":["S0007114510000437"],"URL":"https:\/\/doi.org\/10.1017\/s0007114510000437","relation":{},"ISSN":["0007-1145","1475-2662"],"issn-type":[{"value":"0007-1145","type":"print"},{"value":"1475-2662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,3,1]]}}}