{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T12:17:49Z","timestamp":1780661869364,"version":"3.54.1"},"reference-count":50,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2011,1,28]],"date-time":"2011-01-28T00:00:00Z","timestamp":1296172800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[2011,5,14]]},"abstract":"<jats:p>We examined the relationship between dietary folate intake and periconceptional use of folic acid (FA) supplements, and small-for-gestational age for weight (SGA-W) and height (SGA-H). The study is based on 786 Spanish women aged 16 years or above, who attended the first-term prenatal population-based screening programme (10\u201313 weeks) at the reference hospital \u2018La Fe\u2019, Valencia, with singleton pregnancy. Periconceptional use of FA supplements was categorised as non-users, moderate users (\u00a0\u2264\u00a01\u00a0mg\/d) and high users (&gt;1\u00a0mg\/d). Babies born to mothers who used high doses of FA supplements had a significant reduction in mean birth height compared with babies of non-users (\u03b2\u00a0=\u00a0\u2212\u00a00\u00b753, 95\u00a0% CI \u2212\u00a00\u00b796, \u2212\u00a00\u00b709). As regards weight, mothers using moderate and high doses of FA supplements had lower-birth-weight babies for gestational age than non-users (\u03b2\u00a0=\u00a0\u2212\u00a022\u00b796, 95\u00a0% CI \u2212\u00a0101\u00b714, 55\u00b723; \u03b2\u00a0=\u00a0\u2212\u00a089\u00b772, 95\u00a0% CI \u2212\u00a0188\u00b764, 9\u00b721, respectively), although these decreases were not significant. Results from the multivariate logistic regression models showed that high FA supplement users had a higher significant risk for SGA-H (OR 5\u00b733, 95\u00a0% CI 2\u00b708, 13\u00b77), and that users of moderate doses were not associated with a higher risk of either a SGA-W or a SGA-H baby. In contrast, increased quintiles of the dietary intake of folate were associated with a decreased risk of SGA-W (<jats:italic>P<\/jats:italic>for trend\u00a0=\u00a00\u00b7002), although no association was observed for SGA-H. Our findings suggest that periconceptional use of FA supplements greater than 1\u00a0mg\/d is associated with decreased birth height and may entail a risk of decreased birth weight.<\/jats:p>","DOI":"10.1017\/s0007114510005143","type":"journal-article","created":{"date-parts":[[2011,1,28]],"date-time":"2011-01-28T11:02:17Z","timestamp":1296212537000},"page":"1352-1360","source":"Crossref","is-referenced-by-count":39,"title":["Periconceptional folic acid supplementation and anthropometric measures at birth in a cohort of pregnant women in Valencia, Spain"],"prefix":"10.1017","volume":"105","author":[{"given":"Maria","family":"Pastor-Valero","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva 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