{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T14:55:37Z","timestamp":1772895337327,"version":"3.50.1"},"reference-count":28,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2011,7,4]],"date-time":"2011-07-04T00:00:00Z","timestamp":1309737600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[2012,2,14]]},"abstract":"<jats:p>We evaluated the effects of moderate- to low-intensity physical training during gestation on reflex ontogeny in neonate rats whose mothers were undernourished. Virgin female Wistar rats were divided into four groups as follows: untrained (NT, <jats:italic>n<\/jats:italic> 7); trained (T, <jats:italic>n<\/jats:italic> 7); untrained with a low-protein diet (NT+LP, <jats:italic>n<\/jats:italic> 7); trained with a low-protein diet (T+LP, <jats:italic>n<\/jats:italic> 4). Trained rats were subjected to a protocol of moderate physical training on a treadmill over a period of 4 weeks (5\u00a0d\/week and 60\u00a0min\/d, at 65\u00a0% of VO<jats:sub>2max<\/jats:sub>). After confirming the pregnancy, the intensity and duration of the exercise were reduced. Low-protein groups were provided with an 8\u00a0% casein diet, and controls were provided with a 17\u00a0% casein diet. Their respective offspring were evaluated (during the 10th\u201317th days of postnatal life) in terms of physical feature maturation, somatic growth and reflex ontogeny. Pups born to mothers provided with the low-protein diet during gestation and lactation showed delayed physical feature and reflex maturation and a deficit in somatic growth when compared with controls. However, most of these deficiencies were attenuated in pups of undernourished mothers undergoing training. In conclusion, physical training during gestation attenuates the effects of perinatal undernutrition on some patterns of maturation in the central nervous system during development.<\/jats:p>","DOI":"10.1017\/s0007114511002947","type":"journal-article","created":{"date-parts":[[2011,7,4]],"date-time":"2011-07-04T13:14:08Z","timestamp":1309785248000},"page":"372-377","source":"Crossref","is-referenced-by-count":29,"title":["Maternal low-protein diet-induced delayed reflex ontogeny is attenuated by moderate physical training during gestation in rats"],"prefix":"10.1017","volume":"107","author":[{"given":"Filippe","family":"Falc\u00e3o-Tebas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriano","family":"Bento-Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Ant\u00f4nio Fidalgo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelus Brito","family":"de Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Ant\u00f4nio dos Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Lopes de Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raul","family":"Manh\u00e3es-de-Castro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carol","family":"G\u00f3is Leandro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2011,7,4]]},"reference":[{"key":"S0007114511002947_ref3","doi-asserted-by":"publisher","DOI":"10.1203\/PDR.0b013e318165c005"},{"key":"S0007114511002947_ref15","doi-asserted-by":"publisher","DOI":"10.1136\/adc.46.249.736-d"},{"key":"S0007114511002947_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2003.08.023"},{"key":"S0007114511002947_ref16","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1964.0016"},{"key":"S0007114511002947_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(71)90526-9"},{"key":"S0007114511002947_ref19","doi-asserted-by":"publisher","DOI":"10.1080\/10284150290029197"},{"key":"S0007114511002947_ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2005.10.003"},{"key":"S0007114511002947_ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2010.03.002"},{"key":"S0007114511002947_ref17","first-page":"1251","article-title":"Under nutrition during early life and its effects on animal development and behaviour","volume":"20","author":"Smart","year":"1981","journal-title":"Neuropharmacology"},{"key":"S0007114511002947_ref1","doi-asserted-by":"publisher","DOI":"10.1079\/095442299108728947"},{"key":"S0007114511002947_ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.05.006"},{"key":"S0007114511002947_ref12","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.2009.047621"},{"key":"S0007114511002947_ref14","doi-asserted-by":"publisher","DOI":"10.1079\/BJN20031070"},{"key":"S0007114511002947_ref25","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114508006521"},{"key":"S0007114511002947_ref5","doi-asserted-by":"publisher","DOI":"10.1080\/10284150600772148"},{"key":"S0007114511002947_ref13","first-page":"208","article-title":"Revised Guide for the Care and Use of Laboratory Animals available. 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