{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T11:08:50Z","timestamp":1774436930522,"version":"3.50.1"},"reference-count":75,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2012,8,23]],"date-time":"2012-08-23T00:00:00Z","timestamp":1345680000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[2013,4,14]]},"abstract":"<jats:p>Increasing evidence suggests that high-sensitivity C-reactive protein (hs-CRP) is associated with cardiometabolic risk factors (CMRF) while being also related to micronutrient deficiencies. As part of a project on the double burden of under- and overnutrition in sub-Saharan Africa, we assessed the relationship between hs-CRP and both CMRF and micronutrient deficiencies in a population-based cross-sectional study carried out in the Northern district of Ouagadougou, the capital city of Burkina Faso. We randomly selected 330 households stratified by income tertile. In each income stratum, 110 individuals aged 25\u201360 years and having lived in Ouagadougou for at least 6 months were randomly selected, and underwent anthropometric measurements and blood sample collection. The prevalence of high hs-CRP was 39\u00b74\u00a0%, with no sex difference. Vitamin A-deficient subjects (12\u00b77\u00a0%) exhibited significant risk of elevated hs-CRP (OR 2\u00b75;<jats:italic>P<\/jats:italic>=\u00a00\u00b7015). Serum ferritin was positively correlated with log hs-CRP (<jats:italic>r<\/jats:italic>0\u00b7194;<jats:italic>P<\/jats:italic>=\u00a00\u00b7002). The risk of elevated hs-CRP was significant in subjects with BMI \u2265\u00a025\u00a0kg\/m<jats:sup>2<\/jats:sup>(OR 6\u00b79; 95\u00a0% CI 3\u00b76, 13\u00b73), abdominal obesity (OR 4\u00b76; 95\u00a0% CI 2\u00b72, 7\u00b73) and high body fat (OR 10\u00b72; 95\u00a0% CI 5\u00b71, 20\u00b73) (<jats:italic>P<\/jats:italic>&lt;\u00a00\u00b7001, respectively). Independent predictors of hs-CRP in linear regression models were waist circumference (\u03b2\u00a0=\u00a00\u00b7306;<jats:italic>P<\/jats:italic>=\u00a00\u00b7018) and serum TAG (\u03b2\u00a0=\u00a00\u00b7158;<jats:italic>P<\/jats:italic>=\u00a00\u00b7027). In this sub-Saharan population, hs-CRP was consistently associated with adiposity. Assuming that plasma hs-CRP reflects future risk of cardiovascular events, intervention which reduces CRP, or chronic and acute nutrition conditions associated with it, could be effective in preventing their occurrence particularly in sub-Saharan Africa.<\/jats:p>","DOI":"10.1017\/s0007114512003182","type":"journal-article","created":{"date-parts":[[2012,8,23]],"date-time":"2012-08-23T07:34:50Z","timestamp":1345707290000},"page":"1266-1275","source":"Crossref","is-referenced-by-count":9,"title":["Association of high-sensitivity C-reactive protein with cardiometabolic risk factors and micronutrient deficiencies in adults of Ouagadougou, Burkina Faso"],"prefix":"10.1017","volume":"109","author":[{"given":"Augustin N.","family":"Zeba","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9l\u00e8ne F.","family":"Delisle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e9mentine","family":"Rossier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genevieve","family":"Renier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2012,8,23]]},"reference":[{"key":"S0007114512003182_ref64","volume-title":"Diabetes Atlas","year":"2009"},{"key":"S0007114512003182_ref39","first-page":"326","article-title":"Associations between body mass index and serum levels of C-reactive protein","volume":"99","author":"Kao","year":"2009","journal-title":"S Afr Med J"},{"key":"S0007114512003182_ref44","doi-asserted-by":"publisher","DOI":"10.3945\/jn.108.092700"},{"key":"S0007114512003182_ref49","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjh.0000217847.03208.ba"},{"key":"S0007114512003182_ref43","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2010.02.017"},{"key":"S0007114512003182_ref20","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2008-1595"},{"key":"S0007114512003182_ref30","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/77.2.331"},{"key":"S0007114512003182_ref72","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2009.146"},{"key":"S0007114512003182_ref63","doi-asserted-by":"publisher","DOI":"10.1172\/JCI29069"},{"key":"S0007114512003182_ref56","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000104566.10178.AF"},{"key":"S0007114512003182_ref60","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2010.148833"},{"key":"S0007114512003182_ref70","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.110.005439"},{"key":"S0007114512003182_ref57","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000041046.32962.86"},{"key":"S0007114512003182_ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2007.07.002"},{"key":"S0007114512003182_ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.puhe.2009.07.009"},{"key":"S0007114512003182_ref11","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.18.2063"},{"key":"S0007114512003182_ref24","volume-title":"Etude diagnostique de l'agglom\u00e9ration de Ouagadougou","year":"2007"},{"key":"S0007114512003182_ref69","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9150(02)00233-2"},{"key":"S0007114512003182_ref38","volume-title":"Assessing the Iron Status of Populations: Including Literature Reviews: Report of a Joint WHO\/CDC and Prevention Technical Consultation on the Assessment of Iron Status at the Population Level, 6\u20138 April 2004","year":"2004"},{"key":"S0007114512003182_ref59","doi-asserted-by":"publisher","DOI":"10.1038\/nri2925"},{"key":"S0007114512003182_ref52","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-007-9141-2"},{"key":"S0007114512003182_ref40","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0803035"},{"key":"S0007114512003182_ref33","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000132467.45278.59"},{"key":"S0007114512003182_ref65","article-title":"Plasma retinol: a novel marker for cardiovascular disease mortality in Australian adults","author":"Brazionis","year":"2011","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"S0007114512003182_ref28","volume-title":"Obesity: Preventing and Managing the Global Epidemic. 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