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The objective of the present study was to evaluate provitamin A-enhanced cassava as a source of \u03b2-carotene and vitamin A for healthy adult women. The study was a randomised, cross-over trial of ten American women. The subjects consumed three different porridges separated by 2 week washout periods. Treatment meals (containing 100\u00a0g cassava) included: biofortified cassava (2\u00a0mg \u03b2-carotene) porridge with added oil (15\u00a0ml peanut or rapeseed oil, 20\u00a0g total fat); biofortified cassava porridge without added oil (6\u00a0g total fat); unfortified white cassava porridge with a 0\u00b73\u00a0mg retinyl palmitate reference dose and added oil (20\u00a0g total fat). Blood was collected six times from \u2212\u00a00\u00b75 to 9\u00b75\u00a0h post-feeding. TAG-rich lipoprotein (TRL) plasma was separated by ultracentrifugation and analysed using HPLC with coulometric array electrochemical detection. The AUC for retinyl palmitate increased after the biofortified cassava meals were fed (<jats:italic>P<\/jats:italic>&lt;\u00a00\u00b705). Vitamin A conversion was 4\u00b72 (<jats:sc>sd<\/jats:sc>3\u00b71) and 4\u00b75 (<jats:sc>sd<\/jats:sc>3\u00b71)\u00a0\u03bcg \u03b2-carotene:1\u00a0\u03bcg retinol, with and without added oil, respectively. These results show that biofortified cassava increases \u03b2-carotene and retinyl palmitate TRL plasma concentrations in healthy well-nourished adult women, suggesting that it is a viable intervention food for preventing vitamin A deficiency.<\/jats:p>","DOI":"10.1017\/s0007114512005004","type":"journal-article","created":{"date-parts":[[2013,1,21]],"date-time":"2013-01-21T10:19:35Z","timestamp":1358763575000},"page":"310-320","source":"Crossref","is-referenced-by-count":68,"title":["Biofortified cassava increases \u03b2-carotene and vitamin A concentrations in the TAG-rich plasma layer of American women"],"prefix":"10.1017","volume":"110","author":[{"given":"Michael R.","family":"La Frano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leslie R.","family":"Woodhouse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dustin 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