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All eligible anaemic pre-school children were randomly divided into three groups: group 1 received no intervention, which served as the control group, group 2 received 400 mg single-dose albendazole administration and group 3 received a 60000 \u03bcg vitamin A capsule combined with 400 mg single-dose albendazole at the beginning of the study. The follow-up period was for 6 months. Anthropometry and biochemical index about Fe metabolism were measured before and after intervention. A total of 209 pre-school anaemic children were randomly divided into three intervention groups (sixty-four, sixty-two and sixty for groups 1, 2 and 3, respectively). The mean age of the children in the study was 4\u00b74 (<jats:sc>sd<\/jats:sc> 0\u00b77) years and 50\u00b75 % of the children were female (94\/186). After a follow-up period of 6 months, the levels of serum retinol, ferritin, transferrin receptor-ferritin index and body total Fe content of children in group 3 were significantly higher compared with children in groups 1 and 2 (<jats:italic>P<\/jats:italic>&lt;0\u00b705). Moreover, the proportion of vitamin A deficiency, marginal vitamin A deficiency and Fe deficiency among children in group 3 were markedly lower compared with children in groups 1 and 2 (<jats:italic>P<\/jats:italic>&lt;0\u00b705). Albendazole plus vitamin A administration showed more efficacy on the improvement of serum retinol and Fe metabolic status.<\/jats:p>","DOI":"10.1017\/s0007114516000350","type":"journal-article","created":{"date-parts":[[2016,2,23]],"date-time":"2016-02-23T04:51:48Z","timestamp":1456203108000},"page":"1415-1423","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":11,"title":["Effect of single-dose albendazole and vitamin A supplementation on the iron status of pre-school children in Sichuan, China"],"prefix":"10.1017","volume":"115","author":[{"given":"Ke","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hu Mina","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weizheng","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoling","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice C.","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2016,2,23]]},"reference":[{"key":"S0007114516000350_ref35","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2010.146"},{"key":"S0007114516000350_ref27","doi-asserted-by":"crossref","unstructured":"Kishawi RRE , Soo KL & Abed YA (2015) Anemia among children aged 2\u20135 years in the Gaza Strip-Palestinian: a cross sectional study. 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