{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:07:52Z","timestamp":1790640472875,"version":"4.1.0"},"reference-count":76,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2016,7,25]],"date-time":"2016-07-25T00:00:00Z","timestamp":1469404800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[2016,9,14]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Enteric methane (CH<jats:sub>4<\/jats:sub>) production is a side-effect of herbivore digestion, but it is unknown whether CH<jats:sub>4<\/jats:sub> itself influences digestive physiology. We investigated the effect of adding CH<jats:sub>4<\/jats:sub> to, or reducing it in, the reticulorumen (RR) in a 4\u00d74 Latin square experiment with rumen-fistulated, non-lactating cows, with four treatments: (i) control, (ii) insufflation of CH<jats:sub>4<\/jats:sub> (iCH<jats:sub>4<\/jats:sub>), (iii) N via rumen fistula, (iv) reduction of CH<jats:sub>4<\/jats:sub> via administration of bromochloromethane (BCM). DM intake (DMI), apparent total tract digestibility, digesta mean retention times (MRT), rumen motility and chewing activity, spot breath CH<jats:sub>4<\/jats:sub> emission (CH<jats:sub>4<\/jats:sub>exhal, litre\/kg DMI) as well as CH<jats:sub>4<\/jats:sub> dissolved in rumen fluid (CH<jats:sub>4<\/jats:sub>RRf, \u00b5g\/ml) were measured. Data were analysed using mixed models, including treatment (or, alternatively, CH<jats:sub>4<\/jats:sub>exhal or CH<jats:sub>4<\/jats:sub>RRf) and DMI relative to body mass<jats:sup>0\u00b785<\/jats:sup> (rDMI) as covariates. rDMI was the lowest on the BCM treatment. CH<jats:sub>4<\/jats:sub>exhal was highest for iCH<jats:sub>4<\/jats:sub> and lowest for BCM treatments, whereas only BCM affected (reduced) CH<jats:sub>4<\/jats:sub>RRf. After adjusting for rDMI, CH<jats:sub>4<\/jats:sub>RRf had a negative association with MRT in the gastrointestinal tract but not in the RR, and negative associations with fibre digestibility and measures of rumination activity. Adjusting for rDMI, CH<jats:sub>4<\/jats:sub>exhal had additionally a negative association with particle MRT in the RR and a positive association with rumen motility. Thus, higher rumen levels of CH<jats:sub>4<\/jats:sub> (CH<jats:sub>4<\/jats:sub>exhal or CH<jats:sub>4<\/jats:sub>RRf) were associated with shorter MRT and increased motility. These findings are tentatively interpreted as a feedback mechanism in the ruminant digestive tract that aims at mitigating CH<jats:sub>4<\/jats:sub> losses by shortening MRT at higher CH<jats:sub>4<\/jats:sub>.<\/jats:p>","DOI":"10.1017\/s0007114516002701","type":"journal-article","created":{"date-parts":[[2016,7,25]],"date-time":"2016-07-25T06:27:51Z","timestamp":1469428071000},"page":"763-773","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":17,"title":["Influence of ruminal methane on digesta retention and digestive physiology in non-lactating dairy cattle"],"prefix":"10.1017","volume":"116","author":[{"given":"Marie T.","family":"Dittmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsty 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