{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,8]],"date-time":"2026-11-08T01:46:06Z","timestamp":1794102366127,"version":"4.8.0"},"reference-count":51,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2017,5,2]],"date-time":"2017-05-02T00:00:00Z","timestamp":1493683200000},"content-version":"unspecified","delay-in-days":18,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[2017,4,14]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of this study was to characterise the gut microbiota composition of piglets fed bovine colostrum (BC), milk replacer (MR) or sow milk (SM) in the post-weaning period. Piglets (<jats:italic>n<\/jats:italic>36), 23-d old, were randomly allocated to the three diets. Faecal samples were collected at 23, 25, 27 and 30 d of age. Digesta from the stomach, ileum, caecum and mid-colon was collected at 30 d of age. Bacterial DNA from all samples was subjected to amplicon sequencing of the 16S rRNA gene. Bacterial enumerations by culture and SCFA analysis were conducted as well. BC-piglets had the highest abundance of<jats:italic>Lactococcus<\/jats:italic>in the stomach (<jats:italic>P<\/jats:italic>&lt;0\u00b70001) and ileal (<jats:italic>P<\/jats:italic>&lt;0\u00b70001) digesta, whereas SM-piglets had the highest abundance of<jats:italic>Lactobacillus<\/jats:italic>in the stomach digesta (<jats:italic>P<\/jats:italic>&lt;0\u00b70001). MR-piglets had a high abundance of Enterobacteriaceae in the ileal digesta (<jats:italic>P<\/jats:italic>&lt;0\u00b70001) and a higher number of haemolytic bacteria in ileal (<jats:italic>P<\/jats:italic>=0\u00b70002) and mid-colon (<jats:italic>P<\/jats:italic>=0\u00b7001) digesta than SM-piglets. BC-piglets showed the highest colonic concentration of iso-butyric and iso-valeric acid (<jats:italic>P<\/jats:italic>=0\u00b702). Sequencing and culture showed that MR-piglets were colonised by a higher number of Enterobacteriaceae, whereas the gut microbiota of BC-piglets was characterised by a change in lactic acid bacteria genera when compared with SM-piglets. We conclude that especially the ileal microbiota of BC-piglets had a closer resemblance to that of SM-piglets in regard to the abundance of potential enteric pathogens than did MR-piglets. The results indicate that BC may be a useful substitute for regular milk replacers, and as a feeding supplement in the immediate post-weaning period.<\/jats:p>","DOI":"10.1017\/s0007114517000216","type":"journal-article","created":{"date-parts":[[2017,5,2]],"date-time":"2017-05-02T08:48:02Z","timestamp":1493714882000},"page":"964-978","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":47,"title":["The microbial community of the gut differs between piglets fed sow milk, milk replacer or bovine colostrum"],"prefix":"10.1017","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9797-4180","authenticated-orcid":false,"given":"Ann-Sofie R.","family":"Poulsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadieh","family":"de Jonge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sugiharto","family":"Sugiharto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeppe L.","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Lauridsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria","family":"Canibe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2017,5,2]]},"reference":[{"key":"S0007114517000216_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.livprodsci.2004.07.014"},{"key":"S0007114517000216_ref34","doi-asserted-by":"publisher","DOI":"10.1017\/S0029665107005484"},{"key":"S0007114517000216_ref31","doi-asserted-by":"publisher","DOI":"10.1002\/bimj.200810425"},{"key":"S0007114517000216_ref51","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0019594"},{"key":"S0007114517000216_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0958-6946(97)00022-8"},{"key":"S0007114517000216_ref35","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2014.12"},{"key":"S0007114517000216_ref9","doi-asserted-by":"publisher","DOI":"10.1017\/S1751731114000950"},{"key":"S0007114517000216_ref23","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btr507"},{"key":"S0007114517000216_ref26","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0132783"},{"key":"S0007114517000216_ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-004-1205-4"},{"key":"S0007114517000216_ref10","doi-asserted-by":"publisher","DOI":"10.1017\/S175173110900398X"},{"key":"S0007114517000216_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.livsci.2007.01.009"},{"key":"S0007114517000216_ref40","doi-asserted-by":"publisher","DOI":"10.1016\/j.livsci.2007.01.130"},{"key":"S0007114517000216_ref24","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2604"},{"key":"S0007114517000216_ref15","doi-asserted-by":"publisher","DOI":"10.2527\/jas.2011-3941"},{"key":"S0007114517000216_ref27","volume-title":"vegan: Community Ecology Package. 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