{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T00:40:02Z","timestamp":1792888802019,"version":"4.5.0"},"reference-count":77,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2020,12,29]],"date-time":"2020-12-29T00:00:00Z","timestamp":1609200000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[2021,10,28]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Fe-deficiency anaemia is considered an important public health problem both in wealthier countries and in those of medium and low income, especially in children under 5 years of age. The shortage of studies with national representativity in medium-income countries, such as Brazil, prevents the knowledge of the current situation and its associated factors. We conducted a systematic review and meta-analysis to estimate the pooled prevalence of Fe-deficiency anaemia in Brazilian children under 5 years of age and determined the factors involved in the variability of the estimates of prevalence. We collected fifty-seven studies from the databases MEDLINE, LILACS and Web of Science, along with the reference lists of included articles. We contacted authors for unpublished data. We did not restrict publication timespan and language. This systematic review and meta-analysis was reported according to the guidelines by PRISMA. The pooled prevalence of anaemia in Brazil was 40\u00b72 (95 % CI 36\u00b70, 44\u00b78) %. The age range of the child and the period of data collection were associated with the anaemia prevalence. The pooled prevalence of anaemia was higher in children under 24 months of age (53\u00b75 <jats:italic>v.<\/jats:italic> 30\u00b77 %; <jats:italic>P<\/jats:italic> &lt; 0\u00b7001) and in studies with data collected before 2004 (51\u00b78 <jats:italic>v.<\/jats:italic> 32\u00b76 %; <jats:italic>P<\/jats:italic> = 0\u00b7001). The efforts made by the Brazilian government were successful in the reduction of anaemia in children under 5 years of age in Brazil in the evaluated period. However, prevalence remains beyond acceptable levels for this population group.<\/jats:p>","DOI":"10.1017\/s000711452000522x","type":"journal-article","created":{"date-parts":[[2020,12,29]],"date-time":"2020-12-29T02:30:06Z","timestamp":1609209006000},"page":"1257-1269","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":14,"title":["Prevalence of iron-deficiency anaemia in Brazilian children under 5 years of age: a systematic review and meta-analysis"],"prefix":"10.1017","volume":"126","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5271-7412","authenticated-orcid":false,"given":"Victor N. 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A.","family":"Frota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabela L.","family":"Calado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nayra A. C.","family":"Cantanhede","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvia C. C.","family":"Franceschini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Karina T. 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Doctorate degree, Universidade de S\u00e3o Paulo."},{"key":"S000711452000522X_ref11","volume-title":"Nutritional Anaemias: Tools for Effective Prevention and Control","year":"2017"},{"key":"S000711452000522X_ref46","doi-asserted-by":"publisher","DOI":"10.1590\/1413-81232015212.19072014"},{"key":"S000711452000522X_ref5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1401038"},{"key":"S000711452000522X_ref22","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a116813"},{"key":"S000711452000522X_ref71","doi-asserted-by":"publisher","DOI":"10.1590\/S0021-75572010000600007"},{"key":"S000711452000522X_ref2","doi-asserted-by":"publisher","DOI":"10.1590\/1413-81232014194.00602013"},{"key":"S000711452000522X_ref55","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/3950687"},{"key":"S000711452000522X_ref21","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1186"},{"key":"S000711452000522X_ref17","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2891-12-69"},{"key":"S000711452000522X_ref66","doi-asserted-by":"publisher","DOI":"10.1590\/S1519-38292010000100011"},{"key":"S000711452000522X_ref60","unstructured":"60. Silva, LLS (2017) Fortifica\u00e7\u00e3o da alimenta\u00e7\u00e3o complementar com m\u00faltiplos micronutrientes em p\u00f3 na preven\u00e7\u00e3o da anemia e no estado nutricional de vitamina A e crian\u00e7as na Aten\u00e7\u00e3o B\u00e1sica \u00e0 Sa\u00fade (Fortification of complementary feeding with multiple micronutrients in powder to prevent anaemia and in the nutritional status of vitamin A and children in primary health care). Doctorate degree, Universidade de S\u00e3o Paulo."},{"key":"S000711452000522X_ref32","doi-asserted-by":"publisher","DOI":"10.1590\/0102-311x00243418"},{"key":"S000711452000522X_ref63","first-page":"284","article-title":"Anemia in low-income exclusively breastfed infants","volume":"82","author":"Torres","year":"2006","journal-title":"J Pediatr (Rio J)"},{"key":"S000711452000522X_ref50","unstructured":"50. Pedraza, DF (2005) Anemia em crian\u00e7as e o programa de alimenta\u00e7\u00e3o escolar no contexto da seguran\u00e7a alimentar e nutricional no Brasil (Anaemia in children and the school feeding program in the context of food and nutrition security in Brazil). Doctorate degree, Universidade Federal de Pernambuco."},{"key":"S000711452000522X_ref42","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X2007000600004"},{"key":"S000711452000522X_ref1","volume-title":"The Global Prevalence of Anaemia in 2011","year":"2015"},{"key":"S000711452000522X_ref61","doi-asserted-by":"publisher","DOI":"10.1590\/S0034-89102001000100010"},{"key":"S000711452000522X_ref10","unstructured":"10. WHO (2020) Global Health Observatory \u2013 Anaemia in Children < 5 Years. http:\/\/apps.who.int\/gho\/data\/view.main.ANEMIACHILDRENREGv (accessed February 2020)."},{"key":"S000711452000522X_ref44","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X2005000600041"},{"key":"S000711452000522X_ref52","doi-asserted-by":"publisher","DOI":"10.1590\/1415-52732014000300004"},{"key":"S000711452000522X_ref67","doi-asserted-by":"publisher","DOI":"10.1590\/S0034-89102007000300002"},{"key":"S000711452000522X_ref34","doi-asserted-by":"publisher","DOI":"10.1590\/S1415-52732007000200004"},{"key":"S000711452000522X_ref39","doi-asserted-by":"publisher","DOI":"10.1590\/1415-52732015000200001"}],"container-title":["British Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S000711452000522X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,17]],"date-time":"2021-12-17T14:09:09Z","timestamp":1639750149000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S000711452000522X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,29]]},"references-count":77,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,10,28]]}},"alternative-id":["S000711452000522X"],"URL":"https:\/\/doi.org\/10.1017\/s000711452000522x","relation":{},"ISSN":["0007-1145","1475-2662"],"issn-type":[{"value":"0007-1145","type":"print"},{"value":"1475-2662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,29]]},"assertion":[{"value":"\u00a9 The Author(s), 2020. 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