{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T00:07:18Z","timestamp":1769818038571,"version":"3.49.0"},"reference-count":33,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2021,1,14]],"date-time":"2021-01-14T00:00:00Z","timestamp":1610582400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[2021,11,14]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We aimed to develop and validate a new simple decision support tool (U-TEST) for diagnosis of sarcopenia in orthopaedic patients. We created seventeen candidate original questions to detect sarcopenia in orthopaedic patients with sarcopenia through expert opinions and a semi-structured interview. To derive a decision support tool, a logistic regression model with backward elimination was applied to select variables from the seventeen questions, age and underweight (BMI &lt; 18\u00b75 kg\/m<jats:sup>2<\/jats:sup>). Sarcopenia was defined by Asian Working Group for Sarcopenia 2019 criteria. After assigning a score to each selected variable, the sum of scores was calculated. We evaluated the diagnostic performance of the new tool using a logistic regression model. A bootstrap technique was used for internal validation. Among a total of 1334 orthopaedic patients, sixty-five (4\u00b79 %) patients were diagnosed with sarcopenia. We succeeded in developing a \u2018U-TEST\u2019 with scores ranging from 0 to 11 consisting of values for BMI (Underweight), age (Elderly) and two original questions (\u2018I can\u2019t stand up from a chair without supporting myself with my arms\u2019 (Strength) and \u2018I feel that my arms and legs are thinner than they were in the past\u2019 (Thin)). The AUC was 0\u00b777 (95 % CI 0\u00b771, 0\u00b783). With the optimal cut-off set at 3 or greater based on Youden\u2019s index, the sensitivity and the specificity were 76\u00b71 and 63\u00b76 %, respectively. In orthopaedic patients, our U-TEST scoring with two questions and two simple clinical variables can help to screen for sarcopenia.<\/jats:p>","DOI":"10.1017\/s0007114521000106","type":"journal-article","created":{"date-parts":[[2021,1,14]],"date-time":"2021-01-14T08:37:07Z","timestamp":1610613427000},"page":"1323-1330","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":6,"title":["U-TEST, a simple decision support tool for the diagnosis of sarcopenia in orthopaedic patients: the Screening for People Suffering Sarcopenia in Orthopedic cohort of Kobe study (SPSS-OK)"],"prefix":"10.1017","volume":"126","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9079-821X","authenticated-orcid":false,"given":"Tsukasa","family":"Kamitani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takafumi","family":"Wakita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Wada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyonori","family":"Mizuno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4127-7500","authenticated-orcid":false,"given":"Noriaki","family":"Kurita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,1,14]]},"reference":[{"key":"S0007114521000106_ref11","doi-asserted-by":"publisher","DOI":"10.37737\/ace.1.3_102"},{"key":"S0007114521000106_ref16","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l737"},{"key":"S0007114521000106_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2013.05.018"},{"key":"S0007114521000106_ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-019-1222-x"},{"key":"S0007114521000106_ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2011.01.003"},{"key":"S0007114521000106_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2019.12.012"},{"key":"S0007114521000106_ref9","doi-asserted-by":"publisher","DOI":"10.1590\/1414-431x20198204"},{"key":"S0007114521000106_ref27","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-017-0921-4"},{"key":"S0007114521000106_ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2019.09.002"},{"key":"S0007114521000106_ref14","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2007.09.004"},{"key":"S0007114521000106_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(02)00453-5"},{"key":"S0007114521000106_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2017.04.007"},{"key":"S0007114521000106_ref26","first-page":"117","article-title":"Diagnostic performance of calf circumference, thigh circumference, and SARC-F questionnaire to identify sarcopenia in elderly compared to asian working group for sarcopenia\u2019s diagnostic standard","volume":"51","author":"Mienche","year":"2019","journal-title":"Acta Medica Indones"},{"key":"S0007114521000106_ref1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afq034"},{"key":"S0007114521000106_ref13","unstructured":"13. 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