{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T13:39:01Z","timestamp":1700314741228},"reference-count":71,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T00:00:00Z","timestamp":1636416000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[2022,9,28]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Obesity is associated with increased muscle mass and muscle strength. Methods taking into account the total body mass to reveal obese older individuals at increased risk of functional impairment are needed. Therefore, we aimed to detect methods to identify obese older adults at increased risk of functional impairment. Home-dwelling older adults (<jats:italic>n<\/jats:italic> 417, \u2265 70 years of age) were included in this cross-sectional study. Sex-specific cut-off points for two obesity phenotypes (waist circumference (WC) and body fat mass (FM %)) were used to divide women and men into obese and non-obese groups, and within-sex comparisons were performed. Obese women and men, classified by both phenotypes, had similar absolute handgrip strength (HGS) but lower relative HGS (HGS\/total body mass) (<jats:italic>P<\/jats:italic> &lt; 0\u00b7001) than non-obese women and men, respectively. Women with increased WC and FM %, and men with increased WC had higher appendicular skeletal muscle mass (<jats:italic>P<\/jats:italic> &lt; 0\u00b7001), lower muscle quality (HGS\/upper appendicular muscle mass) (<jats:italic>P<\/jats:italic> &lt; 0\u00b7001), and spent longer time on the stair climb test and the repeated sit-to-stand test (<jats:italic>P<\/jats:italic> &lt; 0\u00b705) than non-obese women and men, respectively. Absolute muscle strength was not able to discriminate between obese and non-obese older adults. However, relative muscle strength in particular, but also muscle quality and physical performance tests, where the total body mass was taken into account or served as an extra load, identified obese older adults at increased risk of functional impairment. Prospective studies are needed to determine clinically relevant cut-off points for relative HGS in particular.<\/jats:p>","DOI":"10.1017\/s0007114521004128","type":"journal-article","created":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T08:15:17Z","timestamp":1636445717000},"page":"1064-1071","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of methods to identify individuals with obesity at increased risk of functional impairment among a population of home-dwelling older adults"],"prefix":"10.1017","volume":"128","author":[{"given":"Anne Lene","family":"Nordengen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linn Kristin Lie","family":"\u00d8yri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stine Marie","family":"Ulven","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Truls","family":"Raastad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirsten Bj\u00f8rklund","family":"Holven","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inger","family":"Ottestad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,11,9]]},"reference":[{"key":"S0007114521004128_ref52","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2001.90.6.2157"},{"key":"S0007114521004128_ref18","doi-asserted-by":"publisher","DOI":"10.1080\/21551197.2018.1564197"},{"key":"S0007114521004128_ref68","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.29.03.06.dc05-1605"},{"key":"S0007114521004128_ref59","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2018.01.025"},{"key":"S0007114521004128_ref63","doi-asserted-by":"publisher","DOI":"10.3233\/IES-2010-0389"},{"key":"S0007114521004128_ref65","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2007.01567.x"},{"key":"S0007114521004128_ref57","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-016-0844-5"},{"key":"S0007114521004128_ref28","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afy169"},{"key":"S0007114521004128_ref61","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2008.02126.x"},{"key":"S0007114521004128_ref17","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.163840"},{"key":"S0007114521004128_ref1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/60.3.324"},{"key":"S0007114521004128_ref26","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-012-0004-5"},{"key":"S0007114521004128_ref32","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glu010"},{"key":"S0007114521004128_ref11","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2004.107"},{"key":"S0007114521004128_ref54","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-020-03228-y"},{"key":"S0007114521004128_ref33","volume-title":"WHO Steps Surveillance Manual: The WHO Stepwise Approach to Chronic Disease Risk Factor Surveillance","year":"2005"},{"key":"S0007114521004128_ref12","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2000.89.1.81"},{"key":"S0007114521004128_ref38","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12544"},{"key":"S0007114521004128_ref22","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0579.2003.00207.x"},{"key":"S0007114521004128_ref31","volume-title":"Obesity: Preventing and Managing the Global Epidemic: Report of a WHO Consultation. WHO Technical Report Series no. 253","year":"2000"},{"key":"S0007114521004128_ref23","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c4467"},{"key":"S0007114521004128_ref51","first-page":"igx008","article-title":"Body composition and physical function in older adults with various comorbidities","volume":"1","author":"Kim","year":"2017","journal-title":"Innovat Aging"},{"key":"S0007114521004128_ref40","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/55.4.M221"},{"key":"S0007114521004128_ref16","doi-asserted-by":"publisher","DOI":"10.3945\/an.116.014506"},{"key":"S0007114521004128_ref48","first-page":"844","article-title":"Relative handgrip strength as a simple tool to evaluate impaired heart rate recovery and a low chronotropic index in obese older women","volume":"11","author":"Silva","year":"2018","journal-title":"Int J Exerc Sci"},{"key":"S0007114521004128_ref41","doi-asserted-by":"publisher","DOI":"10.1177\/0898264310388562"},{"key":"S0007114521004128_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2015.10.022"},{"key":"S0007114521004128_ref50","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/gly178"},{"key":"S0007114521004128_ref3","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.3945\/ajcn.2009.28047","article-title":"Longitudinal study of muscle strength, quality, and adipose tissue infiltration","volume":"90","author":"Delmonico","year":"2009","journal-title":"Am J Clin Nutr"},{"key":"S0007114521004128_ref14","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glr070"},{"key":"S0007114521004128_ref24","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.12508"},{"key":"S0007114521004128_ref34","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0113637"},{"key":"S0007114521004128_ref42","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afq034"},{"key":"S0007114521004128_ref21","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-016-0349-4"},{"key":"S0007114521004128_ref43","doi-asserted-by":"publisher","DOI":"10.1159\/000091824"},{"key":"S0007114521004128_ref19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2007.01632.x"},{"key":"S0007114521004128_ref6","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2318-11-33"},{"key":"S0007114521004128_ref27","doi-asserted-by":"publisher","DOI":"10.1186\/2046-2395-3-9"},{"key":"S0007114521004128_ref25","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9041152"},{"key":"S0007114521004128_ref53","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2013.12.008"},{"key":"S0007114521004128_ref49","doi-asserted-by":"publisher","DOI":"10.1007\/s00592-020-01588-4"},{"key":"S0007114521004128_ref36","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glu039"},{"key":"S0007114521004128_ref71","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-019-0310-7"},{"key":"S0007114521004128_ref67","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114507853347"},{"key":"S0007114521004128_ref47","doi-asserted-by":"publisher","DOI":"10.1123\/ijsnem.2013-0123"},{"key":"S0007114521004128_ref69","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2005.10.049"},{"key":"S0007114521004128_ref60","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2018.04.019"},{"key":"S0007114521004128_ref55","doi-asserted-by":"publisher","DOI":"10.1007\/s40279-015-0305-z"},{"key":"S0007114521004128_ref7","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/61.1.72"},{"key":"S0007114521004128_ref13","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0802955"},{"key":"S0007114521004128_ref37","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-019-04107-8"},{"key":"S0007114521004128_ref58","doi-asserted-by":"publisher","DOI":"10.3390\/nu12030755"},{"key":"S0007114521004128_ref62","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/57.8.M539"},{"key":"S0007114521004128_ref56","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12268"},{"key":"S0007114521004128_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-009-0201-z"},{"key":"S0007114521004128_ref35","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2010.03145.x"},{"key":"S0007114521004128_ref4","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/56.5.B209"},{"key":"S0007114521004128_ref45","doi-asserted-by":"publisher","DOI":"10.1519\/00139143-200831010-00002"},{"key":"S0007114521004128_ref30","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-016-0856-1"},{"key":"S0007114521004128_ref10","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2018.00168"},{"key":"S0007114521004128_ref9","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/80.2.475"},{"key":"S0007114521004128_ref39","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2007.02.004"},{"key":"S0007114521004128_ref20","doi-asserted-by":"publisher","DOI":"10.1046\/j.1532-5415.2003.51105.x"},{"key":"S0007114521004128_ref70","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/57.5.M326"},{"key":"S0007114521004128_ref44","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glr010"},{"key":"S0007114521004128_ref2","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/61.10.1059"},{"key":"S0007114521004128_ref5","doi-asserted-by":"publisher","DOI":"10.1093\/epirev\/mxs006"},{"key":"S0007114521004128_ref66","first-page":"37","article-title":"Obesity definitions in sarcopenic obesity: differences in prevalence, agreement and association with muscle function","volume":"9","author":"Khor","year":"2020","journal-title":"J Frailty Aging"},{"key":"S0007114521004128_ref29","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114518001307"},{"key":"S0007114521004128_ref64","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2891-13-81"},{"key":"S0007114521004128_ref46","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2012.00260"}],"container-title":["British Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007114521004128","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,13]],"date-time":"2022-10-13T04:49:47Z","timestamp":1665636587000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007114521004128\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,9]]},"references-count":71,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,9,28]]}},"alternative-id":["S0007114521004128"],"URL":"https:\/\/doi.org\/10.1017\/s0007114521004128","relation":{},"ISSN":["0007-1145","1475-2662"],"issn-type":[{"value":"0007-1145","type":"print"},{"value":"1475-2662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,9]]},"assertion":[{"value":"\u00a9 The Author(s), 2021. Published by Cambridge University Press on behalf of The Nutrition Society","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}