{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T21:52:54Z","timestamp":1747173174109,"version":"3.40.5"},"reference-count":54,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T00:00:00Z","timestamp":1706832000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Nutr"],"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:p>Ulcerative colitis (UC) is a chronic inflammatory disease involving the colon and rectum. One of the most modifiable environmental factors affecting UC severity is the patient\u2019s dietary pattern. Although the role of dietary patterns on UC aetiology has been investigated previously, its relationship with disease severity has not yet been elucidated. This study examined the association between UC patients\u2019 dietary patterns and disease severity. This cross-sectional study was conducted in 340 UC patients. Using an FFQ, food patterns were assessed. Twenty-five food categories were categorised based on the similarity of the nutrient composition of the food using the factor analysis method. A simple clinical colitis activity index was used to determine disease severity. Three dietary patterns were identified based on the factor analysis: healthy, unhealthy and Western dietary pattern. After adjusting for potential confounding factors, patients who were in the highest tertile of healthy dietary pattern compared with the lowest tertile were 92 % less likely to have severe UC (OR: 0\u00b708; 95 % CI: 0\u00b703, 0\u00b722). Also, those in the highest tertile of the Western dietary pattern were 3\u00b786 times more likely to have severe UC than those in the lowest tertile (OR: 3\u00b786; 95 % CI: 1\u00b786, 8\u00b700). Even after controlling for confounding variables, unhealthy dietary pattern did not increase the risk of severe UC. Our data indicate the beneficial role of healthy dietary pattern in amelioration of disease severity in UC patients. To confirm this association, more studies are needed, especially prospective cohort studies.<\/jats:p>","DOI":"10.1017\/s0007114524000187","type":"journal-article","created":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T09:56:34Z","timestamp":1706867794000},"page":"1-10","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["The association between dietary patterns and disease severity in patients with ulcerative colitis"],"prefix":"10.1017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0640-2142","authenticated-orcid":false,"given":"Mohammad Reza","family":"Amini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8145-3172","authenticated-orcid":false,"given":"Zeinab","family":"Khademi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marieh","family":"Salavatizadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niloufar","family":"Rasaei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nasser","family":"Ebrahimi-Daryani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad","family":"Esmaillzadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1944-0052","authenticated-orcid":false,"given":"Azita","family":"Hekmatdoost","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2024,2,2]]},"reference":[{"key":"S0007114524000187_ref39","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1177\/0003319717721603","article-title":"Western 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Murtagh, A , Cooney, L , Higginbotham, C , et al. (2023) Dietary practices, beliefs, behaviours of adults with inflammatory bowel disease: a cross-sectional study. 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