{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:44:18Z","timestamp":1786999458931,"version":"build-2736575974"},"reference-count":59,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T00:00:00Z","timestamp":1706140800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Nutr"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study evaluated the feasibility and safety of a telehealth delivered exercise plus plant-based protein diet in adults with non-alcoholic fatty liver disease (NAFLD). This was a 12-week, randomised controlled feasibility trial including twenty-eight adults aged &gt; 45 years with NAFLD randomised to a home muscle strengthening program (3 d\/week) with increased protein intake (target \u223c1\u00b72\u20131\u00b75 g\/kg\/d) from predominately plant-based sources and behavioural change support (3\u20134 text messages\/week) (Pro-Ex\n                    <jats:italic>n<\/jats:italic>\n                    14) or usual care (UC,\n                    <jats:italic>n<\/jats:italic>\n                    14). Feasibility was assessed via retention (\u2264 10 % attrition), adherence (exercise \u2265 66 %; recommended daily protein serves \u2265 80 %) and safety (adverse events). Secondary outcomes included macronutrient intake (3 \u00d7 24-h records), weight, moderate-to-vigorous physical activity (MVPA) and 30 s sit-to-stand (STS) performance. Study retention was 89 %. Mean exercise adherence (Pro-Ex) was 52 % with one adverse event from 241 sessions. In Pro-Ex, mean daily plant protein serves increased (0\u00b79 to 1\u00b74\/d) and animal protein decreased (1\u00b75 to 1\u00b72\/d) after 12-weeks, but overall adherence (serves\/day) was 32[RD1] % (plant) and 42 % (animal). Relative to UC, Pro-Ex experienced a mean 2\u00b77 (95 % CI: 0\u00b79, 4\u00b74) increase in 30 s STS number, 46-minute (95 % CI: \u2212153, 245) increase in MVPA, 1\u00b77 kg (95 % CI: \u22123\u00b75, 0\u00b72) decrease in weight, 35\u00b72 g (95 % CI: 11\u00b70, 59\u00b73) increase in protein. In adults with NAFLD a telehealth home exercise and dietary intervention was safe and improved habitual plant and animal protein intake, but overall adherence was modest suggesting more intensive healthcare support may be required.\n                  <\/jats:p>","DOI":"10.1017\/s0007114524000242","type":"journal-article","created":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T00:19:03Z","timestamp":1706141943000},"page":"1-11","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":3,"title":["Delivery of a telehealth supported home exercise program with dietary advice to increase plant-based protein intake in people with non-alcoholic fatty liver disease: a 12-week randomised controlled feasibility trial"],"prefix":"10.1017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2026-9931","authenticated-orcid":false,"given":"Christine L.","family":"Freer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1385-2371","authenticated-orcid":false,"given":"Elena S.","family":"George","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9607-202X","authenticated-orcid":false,"given":"Sze-Yen","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gavin","family":"Abbott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin M.","family":"Daly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2024,1,25]]},"reference":[{"key":"S0007114524000242_ref25","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1186\/s12876-021-01688-7","article-title":"Association of meat consumption with NAFLD risk and liver-related biochemical indexes in older Chinese: a cross-sectional study","volume":"21","author":"Peng","year":"2021","journal-title":"BMC Gastroenterol"},{"key":"S0007114524000242_ref36","doi-asserted-by":"crossref","DOI":"10.4324\/9780203771587","volume-title":"Statistical Power Analysis for the Behavioral Sciences","author":"Cohen","year":"2013"},{"key":"S0007114524000242_ref9","doi-asserted-by":"crossref","first-page":"e14802","DOI":"10.2196\/14802","article-title":"Lifestyle intervention enabled by mobile technology on weight loss in patients with nonalcoholic fatty liver disease: randomized controlled trial","volume":"8","author":"Lim","year":"2020","journal-title":"JMIR Mhealth Uhealth"},{"key":"S0007114524000242_ref2","doi-asserted-by":"crossref","first-page":"219","DOI":"10.2174\/1570161115666170621075619","article-title":"Is non-alcoholic fatty liver disease indeed the hepatic manifestation of metabolic syndrome?","volume":"16","author":"Katsiki","year":"2018","journal-title":"Curr Vasc Pharmacol"},{"key":"S0007114524000242_ref50","doi-asserted-by":"crossref","first-page":"3193","DOI":"10.3390\/nu13093193","article-title":"Are dietary proteins the key to successful body weight management? 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