{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T06:30:34Z","timestamp":1775284234802,"version":"3.50.1"},"reference-count":45,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T00:00:00Z","timestamp":1726617600000},"content-version":"unspecified","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[2024,8,28]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of this study is to investigate whether 25-hydroxyvitamin D (25(OH)D) is associated with periodontitis and tooth loss in older adults. A total of 2346 adults underwent a detailed dental examination as part of the health assessment of a national population study \u2013 The Irish Longitudinal Study of Ageing. 25(OH)D analysis was performed on frozen non-fasting total plasma using LC-MS. The analysis included both multiple logistic regression and multinominal logistic regression to investigate associations between 25(OH)D concentration, periodontitis and tooth loss, adjusting for a range of potential confounders. Results of the analysis found the mean age of participants was 65\u00b73 years (<jats:sc>sd<\/jats:sc> 8\u00b72) and 55\u00b73 % of the group were female. Based on the quintile of 25(OH)D concentration, participants in the lowest <jats:italic>v<\/jats:italic>. highest quintile had an OR of 1\u00b757 (95 % CI 1\u00b716, 2\u00b713; <jats:italic>P<\/jats:italic> &lt; 0\u00b701) of having periodontitis in the fully adjusted model. For tooth loss, participants in the lowest <jats:italic>v<\/jats:italic>. highest quintile of 25(OH)D had a RRR of 1\u00b755 (95 % CI 1\u00b712, 2\u00b713; <jats:italic>P<\/jats:italic> &lt; 0\u00b701) to have 1\u201319 teeth and a RRR of 1\u00b796 (95 % CI 1\u00b720, 3\u00b721; <jats:italic>P<\/jats:italic> &lt; 0\u00b701) to be edentulous, relative to those with \u2265 20 teeth in the fully adjusted models. These findings demonstrate that in this cross-sectional study of older men and women from Ireland, 25(OH)D concentration was associated with both periodontitis and tooth loss, independent of other risk factors.<\/jats:p>","DOI":"10.1017\/s000711452400148x","type":"journal-article","created":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T07:22:57Z","timestamp":1726644177000},"page":"503-511","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Vitamin D, periodontitis and tooth loss in older Irish adults"],"prefix":"10.1017","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8783-8089","authenticated-orcid":false,"given":"Lewis","family":"Winning","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3856-2848","authenticated-orcid":false,"given":"Siobhan","family":"Scarlett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4761-5945","authenticated-orcid":false,"given":"Michael","family":"Crowe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2121-4254","authenticated-orcid":false,"given":"Michael","family":"O\u2019Sullivan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9336-8124","authenticated-orcid":false,"given":"Rose Anne","family":"Kenny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4529-7664","authenticated-orcid":false,"given":"Brian","family":"O\u2019Connell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2024,9,18]]},"reference":[{"key":"S000711452400148X_ref5","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0140-6736(19)31146-8","article-title":"Oral diseases: a global public health challenge","volume":"394","author":"Peres","year":"2019","journal-title":"Lancet"},{"key":"S000711452400148X_ref13","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1056\/NEJMra070553","article-title":"Vitamin D deficiency","volume":"357","author":"Holick","year":"2007","journal-title":"N Engl J 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Geneva: World Health Organization."},{"key":"S000711452400148X_ref36","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1186\/s12903-021-01850-3","article-title":"Serum 25-hydroxyvitamin D is negatively associated with severe periodontitis: a cross-sectional study","volume":"21","author":"Zhou","year":"2021","journal-title":"BMC Oral Health"},{"key":"S000711452400148X_ref43","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0300-5712(96)00029-2","article-title":"The reasons for tooth extractions in adults and their validation","volume":"25","author":"Hull","year":"1997","journal-title":"J Dent"}],"container-title":["British Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S000711452400148X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T12:50:43Z","timestamp":1729687843000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S000711452400148X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,28]]},"references-count":45,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,8,28]]}},"alternative-id":["S000711452400148X"],"URL":"https:\/\/doi.org\/10.1017\/s000711452400148x","relation":{},"ISSN":["0007-1145","1475-2662"],"issn-type":[{"value":"0007-1145","type":"print"},{"value":"1475-2662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,28]]},"assertion":[{"value":"\u00a9 The Author(s), 2024. Published by Cambridge University Press on behalf of The Nutrition Society","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}