{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T04:19:05Z","timestamp":1788322745954,"version":"build-2803163510"},"reference-count":80,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T00:00:00Z","timestamp":1733788800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[2026,3,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Research on nutraceutical and dietary interventions in psychiatry has grown substantially, but progress is hindered by methodological inconsistencies and limited reporting standards. To address this, the International Society for Nutritional Psychiatry Research presents the first guidelines on clinical trial design, conduct, and reporting for future clinical trials in this area. Recommendations were developed using a Delphi process including eighteen researchers with considerable clinical trial expertise and experience in either methodology, nutraceutical, or dietary interventions in psychiatry. These guidelines provide forty-nine recommendations for clinical trial design and outcomes, five for trial reporting, and seven for future research priorities. The recommendations included in these guidelines are designed to inform both nutraceutical and dietary clinical trial interventions in Nutritional Psychiatry. Common themes include an emphasis on the importance of a multidisciplinary research team and integration of co-design processes into the conduct and design of clinical research, methods to improve transparency and replicability of trial outcomes, and measures to address common biases in nutrition trials. Furthermore, we provide recommendations for future research including examining a greater variety of nutraceutical and dietary interventions, scalable delivery models, effectiveness and implementation studies, and the need to investigate these interventions in the prevention and management of less studied psychiatric conditions (e.g. schizophrenia and bipolar disorder). Recommendations included within these guidelines are intended to improve the rigor and clinical relevance of ongoing and future clinical trials in Nutritional Psychiatry.<\/jats:p>","DOI":"10.1017\/s0007114524001946","type":"journal-article","created":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T00:42:49Z","timestamp":1733791369000},"page":"608-620","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":10,"title":["Methodological and reporting recommendations for clinical trials in Nutritional Psychiatry: Guidelines from the International Society for Nutritional Psychiatry Research"],"prefix":"10.1017","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8556-8230","authenticated-orcid":false,"given":"Wolfgang","family":"Marx","sequence":"first","affiliation":[{"name":"Deakin University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjolein","family":"Visser","sequence":"additional","affiliation":[{"name":"Vrije Universiteit Amsterdam"},{"name":"Amsterdam Public Health Research Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Wallace","sequence":"additional","affiliation":[{"name":"University of Ottawa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felice N.","family":"Jacka","sequence":"additional","affiliation":[{"name":"Deakin University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0601-6129","authenticated-orcid":false,"given":"Jessica","family":"Bayes","sequence":"additional","affiliation":[{"name":"Southern Cross University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Francis","sequence":"additional","affiliation":[{"name":"Macquarie University"},{"name":"Royal North Shore Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachelle","family":"Opie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghan","family":"Hockey","sequence":"additional","affiliation":[{"name":"Deakin University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6769-8421","authenticated-orcid":false,"given":"Scott B.","family":"Teasdale","sequence":"additional","affiliation":[{"name":"Discipline of Psychiatry and Mental Health, School of Clinical Medicine, UNSW Sydney"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Almudena","family":"Sanchez Villegas","sequence":"additional","affiliation":[{"name":"Institute of Health Carlos III"},{"name":"Instituto de Investigaci\u00f3n Sanitaria de Navarra (IdiSNA)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4811-5830","authenticated-orcid":false,"given":"Adrienne","family":"O\u2019Neil","sequence":"additional","affiliation":[{"name":"Deakin University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuan-Pin","family":"Su","sequence":"additional","affiliation":[{"name":"China Medical University Hospital"},{"name":"China Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia J.","family":"Rucklidge","sequence":"additional","affiliation":[{"name":"University of Canterbury"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Berk","sequence":"additional","affiliation":[{"name":"Deakin University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Lopresti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Mischoulon","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanette M.","family":"Johnstone","sequence":"additional","affiliation":[{"name":"Oregon Health & Science University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi M.","family":"Staudacher","sequence":"additional","affiliation":[{"name":"Deakin University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2024,12,10]]},"reference":[{"key":"S0007114524001946_ref32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgph.0002312"},{"key":"S0007114524001946_ref28","doi-asserted-by":"crossref","unstructured":"28. 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