{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T14:31:04Z","timestamp":1763389864822,"version":"3.45.0"},"reference-count":49,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T00:00:00Z","timestamp":1758240000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[2025,9,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Few studies have examined the effects of early-life nutrition interventions on adolescent physical activity (PA). We aimed to examine the long-term effects of small-quantity lipid-based nutrient supplements (SQ-LNS) on adolescent PA and sedentary behaviour (SB) and to describe current adolescent PA and SB levels in this cohort. In the International Lipid-Based Nutrient Supplements (iLiNS)-DYAD-Ghana trial, 1320 mothers were enrolled and randomly assigned to one of three conditions: (1) daily iron and folic acid during pregnancy and placebo (calcium) from birth to 6 months postpartum (IFA), (2) multiple micronutrient supplements during pregnancy to 6 months postpartum (MMN) or (3) SQ-LNS during pregnancy to 6 months postpartum (LNS). Infants from mothers in the LNS group received SQ-LNS designed for children from 6 to 18 months. We recruited 11\u201313-year-old adolescents of mothers enrolled in the iLiNS-DYAD-G trial for a 7-d PA and SB assessment using accelerometers (\n                    <jats:italic>n<\/jats:italic>\n                    305) and self-reported PA and SB (\n                    <jats:italic>n<\/jats:italic>\n                    508). We compared the LNS with non-LNS (IFA+MMN) groups using ANCOVA models for the following outcomes: mean vector magnitude counts per minute, PAQ-C score and percentage of time in SB, light PA and moderate-to-vigorous PA (MVPA). There were no significant differences between the LNS and non-LNS groups in any PA outcome in minimally or fully adjusted models. Only approximately 50 % of adolescents met the PA recommendation of 60 min\/d MVPA, with males more active than females; however, there is room for improvement. SQ-LNS in early life does not appear to have a sustained impact on PA or SB.\n                  <\/jats:p>","DOI":"10.1017\/s0007114525105126","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T04:31:43Z","timestamp":1758256303000},"page":"508-517","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["The effects of small-quantity lipid-based nutrient supplements on adolescent physical activity and sedentary behaviour: a follow-up of the International Lipid-Based Nutrient Supplements-DYAD-Ghana trial"],"prefix":"10.1017","volume":"134","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-1916-6218","authenticated-orcid":false,"given":"Jonnatan","family":"Fajardo","sequence":"first","affiliation":[{"name":"University of California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles D.","family":"Arnold","sequence":"additional","affiliation":[{"name":"University of California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mavis O.","family":"Mensah","sequence":"additional","affiliation":[{"name":"University of Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ebenezer","family":"Adjetey","sequence":"additional","affiliation":[{"name":"University of Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maku E.","family":"Demuyakor","sequence":"additional","affiliation":[{"name":"McKing Consulting Corporation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuping","family":"Tan","sequence":"additional","affiliation":[{"name":"University of California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brietta M.","family":"Oaks","sequence":"additional","affiliation":[{"name":"University of Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seth","family":"Adu-Afarwuah","sequence":"additional","affiliation":[{"name":"University of Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda E.","family":"Guyer","sequence":"additional","affiliation":[{"name":"University of California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn G.","family":"Dewey","sequence":"additional","affiliation":[{"name":"University of California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul D.","family":"Hastings","sequence":"additional","affiliation":[{"name":"University of California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth L.","family":"Prado","sequence":"additional","affiliation":[{"name":"University of California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine P.","family":"Stewart","sequence":"additional","affiliation":[{"name":"University of California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2025,9,19]]},"reference":[{"key":"S0007114525105126_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(18)30357-7"},{"volume-title":"Growth Reference Data for 5\u201319 Years","year":"2007","key":"S0007114525105126_ref29"},{"key":"S0007114525105126_ref31","doi-asserted-by":"publisher","DOI":"10.1007\/BF01537962"},{"key":"S0007114525105126_ref39","unstructured":"39. Kowalski, K , Crocker, P , Donen, R , et al. (2004) The Physical Activity Questionnaire for Older Children (PAQ-C) and Adolescents (PAQ-A) Manual. Saskatoon, SK, Canada: University of Saskatchewan."},{"key":"S0007114525105126_ref13","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/nqab276"},{"key":"S0007114525105126_ref25","doi-asserted-by":"publisher","DOI":"10.1093\/heapol\/czl029"},{"key":"S0007114525105126_ref10","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/125.suppl_4.1027S"},{"key":"S0007114525105126_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmrj.2012.09.585"},{"key":"S0007114525105126_ref7","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2010.52"},{"key":"S0007114525105126_ref21","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.114.091546"},{"key":"S0007114525105126_ref18","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114519001636"},{"key":"S0007114525105126_ref28","unstructured":"28. 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Little Rock, AR: Center for Research on Teaching and Learning, University of Arkansas at Little Rock."},{"key":"S0007114525105126_ref11","doi-asserted-by":"publisher","DOI":"10.1111\/mcn.12049"},{"key":"S0007114525105126_ref35","doi-asserted-by":"publisher","DOI":"10.1159\/000492673"},{"key":"S0007114525105126_ref9","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/125.suppl_4.1078S"},{"key":"S0007114525105126_ref30","doi-asserted-by":"publisher","DOI":"10.1207\/SJRA1003_1"},{"key":"S0007114525105126_ref26","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/nxz005"},{"key":"S0007114525105126_ref33","doi-asserted-by":"publisher","DOI":"10.1016\/j.jesf.2022.02.002"},{"key":"S0007114525105126_ref44","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajcnut.2023.05.025"},{"key":"S0007114525105126_ref41","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/17.3.201"},{"key":"S0007114525105126_ref42","doi-asserted-by":"publisher","DOI":"10.1139\/apnm-2013-0173"},{"key":"S0007114525105126_ref47","first-page":"197","article-title":"An exploratory study of physical activity and over-weight in two senior high schools in the Accra Metropolis","volume":"47","author":"Nyawornota","year":"2013","journal-title":"Ghana Med J"},{"key":"S0007114525105126_ref6","doi-asserted-by":"publisher","DOI":"10.1111\/jhn.12306"},{"key":"S0007114525105126_ref40","doi-asserted-by":"publisher","DOI":"10.1111\/ijpo.12033"},{"key":"S0007114525105126_ref43","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2020-102955"},{"key":"S0007114525105126_ref49","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0229012"},{"key":"S0007114525105126_ref12","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/nqab277"},{"key":"S0007114525105126_ref37","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph13100998"},{"volume-title":"Home Observation for Measurement of the Environment","year":"1979","author":"Caldwell","key":"S0007114525105126_ref27"},{"key":"S0007114525105126_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2016.05.011"},{"key":"S0007114525105126_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.smhs.2021.02.001"},{"key":"S0007114525105126_ref8","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1601006"},{"key":"S0007114525105126_ref45","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/nqy303"},{"key":"S0007114525105126_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajcnut.2023.10.033"},{"key":"S0007114525105126_ref46","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-4642(19)30323-2"},{"key":"S0007114525105126_ref48","doi-asserted-by":"publisher","DOI":"10.1123\/jpah.2018-0459"},{"key":"S0007114525105126_ref24","doi-asserted-by":"publisher","DOI":"10.1037\/e576842013-001"},{"key":"S0007114525105126_ref36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jshs.2019.02.005"},{"key":"S0007114525105126_ref22","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.116.134692"},{"key":"S0007114525105126_ref4","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5868-7-40"},{"key":"S0007114525105126_ref34","doi-asserted-by":"publisher","DOI":"10.1186\/s44167-022-00014-0"},{"key":"S0007114525105126_ref15","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/nqab278"},{"key":"S0007114525105126_ref38","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000000771"},{"key":"S0007114525105126_ref32","doi-asserted-by":"publisher","DOI":"10.1080\/17461391.2012.732614"},{"key":"S0007114525105126_ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s004310051070"},{"key":"S0007114525105126_ref16","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-13-176"},{"key":"S0007114525105126_ref23","doi-asserted-by":"publisher","DOI":"10.3945\/jn.110.125716"},{"key":"S0007114525105126_ref2","unstructured":"2. 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Geneva: World Health Organization."},{"key":"S0007114525105126_ref14","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/nqab279"}],"container-title":["British Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007114525105126","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T14:25:49Z","timestamp":1763389549000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007114525105126\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,19]]},"references-count":49,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,9,28]]}},"alternative-id":["S0007114525105126"],"URL":"https:\/\/doi.org\/10.1017\/s0007114525105126","relation":{},"ISSN":["0007-1145","1475-2662"],"issn-type":[{"type":"print","value":"0007-1145"},{"type":"electronic","value":"1475-2662"}],"subject":[],"published":{"date-parts":[[2025,9,19]]},"assertion":[{"value":"\u00a9 The Author(s), 2025. 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