{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:20:13Z","timestamp":1792023613520,"version":"4.4.0"},"reference-count":64,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[2026,6,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study investigated changes in serum folate and B\n                    <jats:sub>12<\/jats:sub>\n                    , and associations with endurance performance and bone outcomes, in women during military training. Women (\n                    <jats:italic>n<\/jats:italic>\n                    137) had serum folate and B\n                    <jats:sub>12<\/jats:sub>\n                    , haematological markers and endurance performance (2\u00b74 km run) measured at the start (week 1) and end (week 13) of British Army basic training. Whole-body areal bone mineral density and markers of bone metabolism were measured at week 1. Training decreased serum folate (mean change (95 % CI), \u22122\u00b73 (\u22123\u00b70, \u22121\u00b76) nmol \u2219 l\n                    <jats:sup>\u22121<\/jats:sup>\n                    ,\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0\u00b7001), B\n                    <jats:sub>12<\/jats:sub>\n                    (\u221216 (\u221232, 0) pmol \u2219 l\n                    <jats:sup>\u22121<\/jats:sup>\n                    ,\n                    <jats:italic>P<\/jats:italic>\n                    = 0\u00b7042), Hb (\u22120\u00b77 (\u22120\u00b79, \u22120\u00b75) g \u2219 dl\n                    <jats:sup>\u22121<\/jats:sup>\n                    ,\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0\u00b7001) and erythrocyte count (\u22120\u00b72 (\u22120\u00b73, \u22120\u00b72) \u00d7 10^9 \u2219 l\n                    <jats:sup>\u22121<\/jats:sup>\n                    ,\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0\u00b7001), but had no effect on mean corpuscular volume (\n                    <jats:italic>P<\/jats:italic>\n                    = 0\u00b7438) or erythrocyte distribution width (\n                    <jats:italic>P<\/jats:italic>\n                    = 0\u00b7088). There was no association between serum folate, serum B\n                    <jats:sub>12<\/jats:sub>\n                    , Hb or erythrocyte count with run time (\n                    <jats:italic>P<\/jats:italic>\n                    \u2265 0\u00b7518). Serum B\n                    <jats:sub>12<\/jats:sub>\n                    was not associated with areal bone mineral density or bone metabolism at week 1 (\n                    <jats:italic>P<\/jats:italic>\n                    \u2265 0\u00b7152). Higher serum folate was associated with lower plasma c-telopeptide cross-links of type I collagen (standardised\n                    <jats:italic>\u03b2<\/jats:italic>\n                    (95 % CI) = \u22120\u00b731 (\u22120\u00b748, \u22120\u00b715),\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0\u00b7001), but not whole-body bone mineral density or plasma procollagen type I N-terminal propeptide (\n                    <jats:italic>P<\/jats:italic>\n                    \u2265 0\u00b7152). Serum folate and B\n                    <jats:sub>12<\/jats:sub>\n                    decreased after military training in women, resulting in a high prevalence of folate deficiencies at the end of training. Low serum folate may contribute to increased bone resorption, the implications of which are unclear.\n                  <\/jats:p>","DOI":"10.1017\/s0007114526106515","type":"journal-article","created":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T05:26:00Z","timestamp":1770960360000},"page":"1175-1184","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Folate and B\n                    <sub>12<\/sub>\n                    status in women during British Army basic training: a prospective cohort study exploring implications for endurance performance and bone density and metabolism"],"prefix":"10.1017","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1120-8777","authenticated-orcid":false,"given":"Thomas J.","family":"O\u2019Leary","sequence":"first","affiliation":[{"name":"Army Health and Performance Research, Army Headquarters"},{"name":"UCL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah L.","family":"Waters","sequence":"additional","affiliation":[{"name":"Army Health and Performance Research, Army Headquarters"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte V.","family":"Coombs","sequence":"additional","affiliation":[{"name":"Army Health and Performance Research, Army Headquarters"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Jackson","sequence":"additional","affiliation":[{"name":"Army Health and Performance Research, Army Headquarters"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel M.","family":"Izard","sequence":"additional","affiliation":[{"name":"Ministry of Defence"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil P.","family":"Walsh","sequence":"additional","affiliation":[{"name":"Liverpool John Moores University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7922-5549","authenticated-orcid":false,"given":"Alexander T.","family":"Carswell","sequence":"additional","affiliation":[{"name":"University of East Anglia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel J.","family":"Oliver","sequence":"additional","affiliation":[{"name":"Bangor University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan C. 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