{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T03:09:14Z","timestamp":1789009754813,"version":"build-2803163510"},"reference-count":38,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[2026,7,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Iodine is a component of thyroid hormones and essential for neurological development. To evaluate the iodine nutritional status of pregnant women residing in Veneto and the possible role of thyroglobulin (Tg) as a proxy. 528 pregnant women in the third trimester of pregnancy were consecutively enrolled in this cross-sectional study and were asked to provide an early-morning spot urine sample (for UI\/Creat) and a blood sample (for thyroid function and Tg). They also completed a questionnaire. Infant anthropometric data at birth were obtained. Median UI\/Creat was 112\u00b78 \u03bcg\/g. 34\u00b71 % of women had a UI\/Creat \u2265 150 \u03bcg\/g. Iodised salt (IS) was used by 76\u00b79 % of women, iodine-containing supplements (ICS) by 74\u00b72 % and cow\u2019s milk was regularly consumed by 46\u00b70 %. At multivariable analysis, consumption of regular cow\u2019s milk and ICS were significant predictors of UI\/Creat \u2265 150 \u03bcg\/g (OR 1\u00b757, 95 % CI: 1\u00b706, 2\u00b732 and OR: 2\u00b783, 95 % CI: 1\u00b766, 4\u00b782, respectively). The median Tg value was lower among the iodine-sufficient than among the iodine-deficient women (\n                    <jats:italic>P<\/jats:italic>\n                    = 0\u00b7005). At multiple linear regression analysis, Tg was among the factors associated with weight (\n                    <jats:italic>\u03b2<\/jats:italic>\n                    = \u201381\u00b783,\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0\u00b7001) and length (\n                    <jats:italic>\u03b2<\/jats:italic>\n                    = \u20130\u00b73,\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0\u00b701) at birth, although weakly. Tg was a factor associated with pre-term delivery (OR: 1\u00b752, 95 % CI: 1\u00b720, 1\u00b792). Regular use of cow\u2019s milk and ICS is a factor associated with UI\/Creat \u2265 150 \u03bcg\/g. Tg was associated with iodine status and pregnancy outcomes, although it had only a modest discriminative ability for sufficiency.\n                  <\/jats:p>","DOI":"10.1017\/s0007114526106989","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T02:31:01Z","timestamp":1774492261000},"page":"135-144","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Thyroglobulin as a proxy for iodine status in pregnancy"],"prefix":"10.1017","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6946-9673","authenticated-orcid":false,"given":"Simona","family":"Censi","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00240q980","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Padua"},{"id":[{"id":"https:\/\/ror.org\/04bhk6583","id-type":"ROR","asserted-by":"publisher"}],"name":"Padua University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Messina","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00240q980","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Padua"},{"id":[{"id":"https:\/\/ror.org\/04bhk6583","id-type":"ROR","asserted-by":"publisher"}],"name":"Padua University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Arcara","sequence":"additional","affiliation":[{"name":"IRCCS San Camillo Hospital"},{"name":"University of Padua"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edoardo","family":"Ruggeri","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00240q980","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Padua"},{"id":[{"id":"https:\/\/ror.org\/04bhk6583","id-type":"ROR","asserted-by":"publisher"}],"name":"Padua University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Clausi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00240q980","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Padua"},{"id":[{"id":"https:\/\/ror.org\/04bhk6583","id-type":"ROR","asserted-by":"publisher"}],"name":"Padua University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilaria","family":"Piva","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00240q980","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Padua"},{"id":[{"id":"https:\/\/ror.org\/04bhk6583","id-type":"ROR","asserted-by":"publisher"}],"name":"Padua University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacopo","family":"Manso","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00240q980","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Padua"},{"name":"University Hospital S. Maria della Misericordia of Udine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Basso","sequence":"additional","affiliation":[{"name":"University of Padua"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Merante-Boschin","sequence":"additional","affiliation":[{"name":"University of Padua"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loris","family":"Bertazza","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00240q980","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Padua"},{"id":[{"id":"https:\/\/ror.org\/04bhk6583","id-type":"ROR","asserted-by":"publisher"}],"name":"Padua University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susi","family":"Barollo","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00240q980","id-type":"ROR","asserted-by":"publisher"}],"name":"University of 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Author(s), 2026. Published by Cambridge University Press on behalf of The Nutrition Society","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}