{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T09:06:31Z","timestamp":1790672791049,"version":"4.1.0"},"reference-count":26,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Nutr"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Individuals with inflammatory bowel disease (IBD) are at continuous risk of malnutrition, which significantly impacts their prognosis. This study aimed to evaluate the effects of a high-protein diet (HPD) and a high-protein enteral-supplemented diet on disease severity and nutritional status in IBD patients. Forty-eight IBD patients with malnutrition (18\u201364 years) were assigned to a HPD (\n                    <jats:italic>n<\/jats:italic>\n                    24) or a high-protein enteral-supplemented diet (\n                    <jats:italic>n<\/jats:italic>\n                    24) for 12 weeks. Nutritional Risk Screening (NRS-2002), disease activity (CDAI\/Mayo) and anthropometric parameters were evaluated at baseline, week 6 and week 12. In the overall study population, significant differences were found between baseline NRS-2002 and disease severity scores (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0\u00b7001). Across all study participants, the prevalence of severe malnutrition decreased from 79\u00b72 % to 45\u00b78 %, and all scale scores declined by the end of the study. In the HPD group, NRS decreased from 2\u00b775 (\n                    <jats:sc>sd<\/jats:sc>\n                    0\u00b779) to 2\u00b717 (\n                    <jats:sc>sd<\/jats:sc>\n                    0\u00b748) and in the enteral-supplemented group from 3\u00b738 (\n                    <jats:sc>sd<\/jats:sc>\n                    0\u00b758) to 2\u00b792 (\n                    <jats:sc>sd<\/jats:sc>\n                    0\u00b772) (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0\u00b7001). Both groups gained weight, with greater increase in the enteral-supplemented group (6\u00b724 (\n                    <jats:sc>sd<\/jats:sc>\n                    1\u00b770) kg\n                    <jats:italic>v<\/jats:italic>\n                    . 3\u00b755 (\n                    <jats:sc>sd<\/jats:sc>\n                    1\u00b772) kg,\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0\u00b7001). Planned dietary interventions were found to have a positive impact on both disease progression and malnutrition. When high-protein content is supported by enteral products, dietary therapy may be more effective.\n                  <\/jats:p>","DOI":"10.1017\/s0007114526108472","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T08:39:50Z","timestamp":1790671190000},"page":"1-9","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["The effect of nutritional support on clinical disease progress and malnutrition in inflammatory bowel patients"],"prefix":"10.1017","author":[{"given":"K\u00fcbra","family":"Derya \u0130pek","sequence":"first","affiliation":[{"name":"Istanbul Okan University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3497-567X","authenticated-orcid":false,"given":"Hande","family":"\u00d6ng\u00fcn Y\u0131lmaz","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02mtr7g38","id-type":"ROR","asserted-by":"publisher"}],"name":"Bandirma Onyedi Eyl\u00fcl University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"S0007114526108472_ref2","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjaa215"},{"key":"S0007114526108472_ref14","doi-asserted-by":"publisher","DOI":"10.3164\/jcbn.14-95"},{"key":"S0007114526108472_ref17","first-page":"415","article-title":"ESPEN guidelines for nutrition screening","volume":"22","author":"Kondrup","year":"2002","journal-title":"Clin Nutr. 2003"},{"key":"S0007114526108472_ref16","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.20520"},{"key":"S0007114526108472_ref26","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v25.i28.3823"},{"key":"S0007114526108472_ref9","doi-asserted-by":"publisher","DOI":"10.1177\/0148607115612054"},{"key":"S0007114526108472_ref24","doi-asserted-by":"publisher","DOI":"10.1177\/0884533613487218"},{"key":"S0007114526108472_ref12","first-page":"166","article-title":"\u0130nflamatuvar hastal\u0131klar\u0131nda nutrisyon","volume":"16","author":"\u00dcnal","year":"2014","journal-title":"G\u00fcncel Gastroenteroloji"},{"key":"S0007114526108472_ref5","doi-asserted-by":"publisher","DOI":"10.1155\/2005\/269076"},{"key":"S0007114526108472_ref18","first-page":"85","volume-title":"Hastal\u0131klarda beslenme tedavisi","author":"Pekcan","year":"2013"},{"key":"S0007114526108472_ref20","doi-asserted-by":"publisher","DOI":"10.1177\/0148607110381267"},{"key":"S0007114526108472_ref3","volume-title":"Understanding Crohn disease and ulcerative colitis","author":"Zonderman","year":"2009"},{"key":"S0007114526108472_ref11","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/197167"},{"key":"S0007114526108472_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(79)90384-6"},{"key":"S0007114526108472_ref4","first-page":"112","article-title":"\u0130nflamatuvar ba\u011f\u0131rsak hastal\u0131klar\u0131nda epidemiyolojik \u00f6zellikler ve hastal\u0131k fark\u0131ndal\u0131\u011f\u0131; \u0130zmir \u00f6rne\u011fi ile kesitsel bir \u00e7al\u0131\u015fma","volume":"18","author":"\u00d6zg\u00fcrsoy Uran","year":"2019","journal-title":"Turk J Acad Gastroenterol"},{"key":"S0007114526108472_ref7","doi-asserted-by":"publisher","DOI":"10.21037\/atm-22-1126"},{"key":"S0007114526108472_ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclnm.2008.02.004"},{"key":"S0007114526108472_ref23","first-page":"321","article-title":"Enteral nutrition improves health-related quality of life in Crohn\u2019s disease patients with long disease duration","volume":"56","author":"Kuriyama","year":"2009","journal-title":"Hepatogastroenterology"},{"key":"S0007114526108472_ref1","doi-asserted-by":"publisher","DOI":"10.1586\/eci.10.52"},{"key":"S0007114526108472_ref8","doi-asserted-by":"publisher","DOI":"10.1186\/s12937-016-0178-5"},{"key":"S0007114526108472_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2016.09.004"},{"key":"S0007114526108472_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2006.02.007"},{"key":"S0007114526108472_ref6","doi-asserted-by":"publisher","DOI":"10.1002\/ueg2.12566"},{"key":"S0007114526108472_ref19","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/8646495"},{"key":"S0007114526108472_ref22","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjx102"},{"key":"S0007114526108472_ref25","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/6360319"}],"container-title":["British Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007114526108472","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T08:39:52Z","timestamp":1790671192000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007114526108472\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,29]]},"references-count":26,"alternative-id":["S0007114526108472"],"URL":"https:\/\/doi.org\/10.1017\/s0007114526108472","relation":{},"ISSN":["0007-1145","1475-2662"],"issn-type":[{"value":"0007-1145","type":"print"},{"value":"1475-2662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,29]]},"assertion":[{"value":"\u00a9 The Author(s), 2026. Published by Cambridge University Press on behalf of The Nutrition Society","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}