{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:20:48Z","timestamp":1760955648030},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2007,3,9]],"date-time":"2007-03-09T00:00:00Z","timestamp":1173398400000},"content-version":"unspecified","delay-in-days":11451,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[1975,11]]},"abstract":"<jats:p>1. Seven groups of young turbot (<jats:italic>Scophthalmus maximus<\/jats:italic>) were given diets containing graded levels of thiamin (0.19\u201350 mg\/kg) for 16 weeks and their growth rate was measured during this period.<\/jats:p><jats:p>2. Good growth was obtained on all these treatments except in the group given the lowest dietary thiamin level (0.19 mg\/kg). These fish grew normally until the 12th week but thereafter their weight did not increase.<\/jats:p><jats:p>3. Measurements of erythrocyte transketolase (sedoheptulose-7-phosphate: D-glyceraldehyde-3-phosphate glycolaldehydetransferase;<jats:italic>EC<\/jats:italic>2.2.1.1) activity at the end of the experiment and of percentage stimulation of erythrocyte transketolase by thiamin pyrophosphate indicated that the apoenzyme was saturated with coenzyme at a dietary thiamin level of 2.6 mg\/kg, but not at 1.1 mg\/kg.<\/jats:p><jats:p>4. An 8th group of turbot given the thiamin antagonist pyrithiamin (40 mg\/kg diet) grew normally for 6 weeks. Thereafter mortalities began to occur and all fish died by the 10th week. No clear-cut signs of thiamin deficiency were observed.<\/jats:p><jats:p>5. The dietary thiamin requirement of turbot is much lower than published requirements of freshwater fish other than carp (<jats:italic>Cyprinus carpio<\/jats:italic>) and appears to be between 0.6 and 2.6 mg\/kg diet.<\/jats:p>","DOI":"10.1017\/s000711457500044x","type":"journal-article","created":{"date-parts":[[2016,7,27]],"date-time":"2016-07-27T14:37:00Z","timestamp":1469630220000},"page":"383-390","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":44,"title":["Studies on the nutrition of marine flatfish. The thiamin requirement of turbot (<i>Scophthalmus maximus<\/i>)"],"prefix":"10.1017","volume":"34","author":[{"given":"C. B.","family":"Cowey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. W.","family":"Adron","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Knox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. T.","family":"Ball","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,3,9]]},"reference":[{"key":"S000711457500044X_ref009","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-319650-7.50007-9"},{"key":"S000711457500044X_ref002","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/78.2.179"},{"key":"S000711457500044X_ref013","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3002(58)90192-6"},{"key":"S000711457500044X_ref007","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19720055"},{"key":"S000711457500044X_ref008","first-page":"169","volume":"9","author":"Euselsi","year":"1950","journal-title":"Fedn Proc. Fedn Am. Socs exp. Biol."},{"key":"S000711457500044X_ref011","doi-asserted-by":"publisher","DOI":"10.2331\/suisan.36.791"},{"key":"S000711457500044X_ref015","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19730047"},{"key":"S000711457500044X_ref005","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19740038"},{"key":"S000711457500044X_ref006","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19750026"},{"key":"S000711457500044X_ref016","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/80.4.381"},{"key":"S000711457500044X_ref001","doi-asserted-by":"publisher","DOI":"10.2331\/suisan.35.459"},{"key":"S000711457500044X_ref010","first-page":"1186","volume-title":"The Enzymes","volume":"1","author":"Harris","year":"1951"},{"key":"S000711457500044X_ref003","first-page":"242","volume":"23","author":"Brin","year":"1964","journal-title":"Fedn Proc. Fedn Am. Socs exp. Biol."},{"key":"S000711457500044X_ref004","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/71.3.273"},{"key":"S000711457500044X_ref014","volume-title":"Nutrient Requirements of Domestic Animals No. 11, Nutrient Requirements of Trout, Salmon and Catfish","year":"1973"},{"key":"S000711457500044X_ref012","doi-asserted-by":"publisher","DOI":"10.1016\/0044-8486(73)90142-7"},{"key":"S000711457500044X_ref017","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0021-9258(18)43182-1","volume":"155","author":"Sarett","year":"1944","journal-title":"J. biol. Chem."}],"container-title":["British Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S000711457500044X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,3]],"date-time":"2022-07-03T23:42:26Z","timestamp":1656891746000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S000711457500044X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975,11]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1975,11]]}},"alternative-id":["S000711457500044X"],"URL":"https:\/\/doi.org\/10.1017\/s000711457500044x","relation":{},"ISSN":["0007-1145","1475-2662"],"issn-type":[{"value":"0007-1145","type":"print"},{"value":"1475-2662","type":"electronic"}],"subject":[],"published":{"date-parts":[[1975,11]]},"assertion":[{"value":"Copyright \u00a9 The Nutrition Society 1975","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}