{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T04:04:00Z","timestamp":1792641840182,"version":"4.5.0"},"reference-count":38,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:00:00Z","timestamp":1759104000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Bull. Entomol. Res."],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Natural enemies serve a crucial role in crop protection through the regulation of pest population dynamics.\n                    <jats:italic>Cyrtorhinus lividipennis<\/jats:italic>\n                    is an important natural enemy of rice planthoppers. Fatty acid synthase (FAS), a multifunctional enzyme crucial for fatty acid biosynthesis, serves as a vital energy source for insect reproduction. However, the function of FAS in the reproductive processes of\n                    <jats:italic>C. lividipennis<\/jats:italic>\n                    remains incompletely understood. In this study, the\n                    <jats:italic>ClFAS<\/jats:italic>\n                    gene was successfully cloned from\n                    <jats:italic>C. lividipennis<\/jats:italic>\n                    . The open reading frame of\n                    <jats:italic>ClFAS<\/jats:italic>\n                    was 7224 bp, encoding a putative protein of 2407 amino acids. The expression levels of\n                    <jats:italic>ClFAS<\/jats:italic>\n                    were notably elevated in the fifth-instar nymphs, adults, as well as in the fat body and ovaries of female individuals. Silencing of\n                    <jats:italic>ClFAS<\/jats:italic>\n                    resulted in a reduction of 58.4%, 34.6%, and 49.0% in the expression levels of\n                    <jats:italic>ClVg<\/jats:italic>\n                    at 1-, 2-, and 3-days post-dsRNA injection, respectively. Furthermore, RNA interference (RNAi)-mediated depletion of\n                    <jats:italic>ClFAS<\/jats:italic>\n                    not only suppressed the Vg protein expression but also significantly impaired oocyte maturation and ovarian development. The fecundity of dsFAS-treated\n                    <jats:italic>C. lividipennis<\/jats:italic>\n                    females was markedly reduced by 49.5%, accompanied by significant decreases of 32.7% in oviposition duration and 26.3% in female adult lifespan. Our findings showed that ClFAS positively regulates the reproduction of\n                    <jats:italic>C. lividipennis<\/jats:italic>\n                    by promoting vitellogenesis and ovarian development, which provides valuable insights into how lipid metabolism governs fecundity in predatory insects.\n                  <\/jats:p>","DOI":"10.1017\/s0007485325100473","type":"journal-article","created":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T12:20:01Z","timestamp":1759148401000},"page":"75-82","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":2,"title":["Functional characterization of fatty acid synthase gene (\n                    <i>FAS<\/i>\n                    ) in the reproduction of mirid predator,\n                    <i>Cyrtorhinus lividipennis<\/i>\n                    (Hemiptera: Miridae)"],"prefix":"10.1017","volume":"116","author":[{"given":"Kui","family":"Hu","sequence":"first","affiliation":[{"name":"Yangzhou University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Wang","sequence":"additional","affiliation":[{"name":"Yangzhou University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Peng","sequence":"additional","affiliation":[{"name":"Yangzhou University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuancui","family":"Zhong","sequence":"additional","affiliation":[{"name":"Yangzhou University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijie","family":"Xu","sequence":"additional","affiliation":[{"name":"Yangzhou University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruidong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Yangzhou 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