{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T12:21:05Z","timestamp":1791202865162,"version":"4.2.0"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T00:00:00Z","timestamp":1172793600000},"content-version":"vor","delay-in-days":305,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2006,5]]},"abstract":"<jats:p>We present a prospective study at school age of neuropsychiatric and neurodevelopmental outcome of language delay suspected at child health screening around 30 months of age. In a community sample, 25 children (21 males, 4 females) screening positive and 80 children (38 males, 42 females) screening negative for speech and language problems at age 30 months were examined in detail for language disorders at age 6 years. The screen\u2010positive children were then followed for another year and underwent in\u2010depth neuropsychiatric examination by assessors blind to the results of previous testing. Detailed follow\u2010up results at age 7 years were available for 21 children. Thirteen of these 21 children (62%) had a major neuropsychiatric diagnosis (autism, atypical autism, Asperger's syndrome, attention\u2010deficit\u2010hyperactivity disorder [ADHD]), or combinations of these. Two further children (10%) had borderline IQ with no other major diagnosis. We conclude that children in the general population who screen positive for speech and language problems before age 3 years appear to be at very high risk of autism spectrum disorders or ADHD, or both, at 7 years of age. Remaining language problems at age 6 years strongly predict the presence of neuropsychiatric or neurodevelopmental disorders at age 7 years.<\/jats:p>","DOI":"10.1017\/s0012162206000788","type":"journal-article","created":{"date-parts":[[2006,4,11]],"date-time":"2006-04-11T12:43:49Z","timestamp":1144759429000},"page":"361-366","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":112,"title":["Neuropsychiatric and neurodevelopmental outcome of children at age 6 and 7 years who screened positive for language problems at 30 months"],"prefix":"10.1111","volume":"48","author":[{"given":"Carmela","family":"Miniscalco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gudrun","family":"Nygren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bibbi","family":"Hagberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"Kadesj\u00f6","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Gillberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,3,2]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.328.7441.702"},{"key":"e_1_2_2_3_1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"1994"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1987.tb02106.x"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1044\/jshd.5102.98"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199606000-00022"},{"key":"e_1_2_2_7_1","volume-title":"Test of Reception of Grammar (T.R.O.G.)","author":"Bishop DVM","year":"1989"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/13682828909011951"},{"key":"e_1_2_2_9_1","volume-title":"Uncommon Understanding. 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Summary of Main Findings","author":"Law J","year":"1998"},{"key":"e_1_2_2_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/136828200247133"},{"key":"e_1_2_2_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2000.tb00069.x"},{"key":"e_1_2_2_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1997.tb08615.x"},{"key":"e_1_2_2_25_1","volume-title":"OLAF\u2010 Ordl\u00e4sning, Avkodning","author":"Magnusson E","year":"2003"},{"key":"e_1_2_2_26_1","first-page":"324","article-title":"The Swedish Association of Medicine","volume":"10","author":"Miniscalco C","year":"1997","journal-title":"Hygeica"},{"key":"e_1_2_2_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/080352501300067776"},{"key":"e_1_2_2_28_1","unstructured":"MiniscalcoC. (2003)Language impairment in Swedish children \u2010 a survey of 6\u2010year\u2010olds screened for developmental language disability at 2.5 and 4 years of age. (Thesis). 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A prospective longitudinal epidemiological study of total age cohort of children living in Uppsala at 4 7 and 9 years of age. (Thesis). 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