{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T20:34:54Z","timestamp":1791059694625,"version":"4.1.0"},"reference-count":25,"publisher":"Hindawi Limited","issue":"2","license":[{"start":{"date-parts":[[2009,4,14]],"date-time":"2009-04-14T00:00:00Z","timestamp":1239667200000},"content-version":"unspecified","delay-in-days":14258,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genet. Res."],"published-print":{"date-parts":[[1970,4]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The frequency and nature of the changes in \u2018state\u2019 of the mouse X-chromosome controlling element (inactivation centre) have been investigated on an inbred background. The results indicate with near-certainty that meiotic crossing over is the responsible mechanism and that the frequency of recombination between the<jats:italic>T<\/jats:italic>(<jats:italic>1; X<\/jats:italic>)<jats:italic>Ct<\/jats:italic>breakpoint and the locus of the controlling element is approximately 3%. Maize-type \u2018changes in state\u2019 may occur under other experimental conditions. The data do not distinguish on which side of the autosomal insertion the element lies but when combined with observations of other investigators suggest that the location must be on the<jats:italic>Mo-Ta<\/jats:italic>side and very close to<jats:italic>Ta<\/jats:italic>.<\/jats:p>","DOI":"10.1017\/s0016672300001518","type":"journal-article","created":{"date-parts":[[2009,9,17]],"date-time":"2009-09-17T07:54:10Z","timestamp":1253174050000},"page":"183-195","source":"Crossref","is-referenced-by-count":34,"title":["Controlling elements in the mouse X-chromosome"],"prefix":"10.1155","volume":"15","author":[{"given":"B. M.","family":"Cattanach","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. N.","family":"Perez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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Location in the linkage map"],"short-title":[],"issued":{"date-parts":[[1970,4]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1970,4]]}},"alternative-id":["S0016672300001518"],"URL":"https:\/\/doi.org\/10.1017\/s0016672300001518","relation":{},"ISSN":["0016-6723","1469-5073"],"issn-type":[{"value":"0016-6723","type":"print"},{"value":"1469-5073","type":"electronic"}],"subject":[],"published":{"date-parts":[[1970,4]]}}}