{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T18:10:28Z","timestamp":1698516628604},"reference-count":27,"publisher":"Hindawi Limited","issue":"3","license":[{"start":{"date-parts":[[2009,4,14]],"date-time":"2009-04-14T00:00:00Z","timestamp":1239667200000},"content-version":"unspecified","delay-in-days":5978,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genet. Res."],"published-print":{"date-parts":[[1992,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The Sxr (sex-reversed) region that carries a copy of the mouse Y chromosomal testis-determining gene can be attached to the distal end of either the Y or the X chromosome. During male meiosis, Sxr recombined freely between the X and Y chromosomes, with an estimated recombination frequency not significantly different from 50% in either direction. During female meiosis, Sxr recombined freely between the X chromosome to which it was attached and an X-autosome translocation. A male mouse carrying the original Sxr<jats:sup>a<\/jats:sup>region on its Y chromosome, and the shorter Sxr<jats:sup>b<\/jats:sup>variant on the X, also showed 50% recombination between the sex chromosomes. Evidence of unequal crossing-over between the two Sxr regions was obtained: using five markers deleted from Sxr<jats:sup>b<\/jats:sup>, 3 variant Sxr regions were detected in 159 progeny (1\u00b79%). Four other variants (one from the original cross and three from later generations) were presumed to have been derived from illegitimate pairing and crossing-over between Sxr<jats:sup>b<\/jats:sup>and the homologous region on the short arm of the Y chromosome. The generation of new variants throws light on the arrangement of gene loci and other markers within the short arm of the mouse Y chromosome.<\/jats:p>","DOI":"10.1017\/s0016672300030925","type":"journal-article","created":{"date-parts":[[2009,9,17]],"date-time":"2009-09-17T07:28:04Z","timestamp":1253172484000},"page":"175-184","source":"Crossref","is-referenced-by-count":7,"title":["Recombination between the X and Y chromosomes and the Sxr region of the mouse"],"prefix":"10.1155","volume":"60","author":[{"given":"Anne","family":"McLaren","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Simpson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin E.","family":"Bishop","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael 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