{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T07:28:24Z","timestamp":1791012504950,"version":"4.1.0"},"reference-count":0,"publisher":"Hindawi Limited","issue":"1","license":[{"start":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T00:00:00Z","timestamp":1032134400000},"content-version":"unspecified","delay-in-days":46,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genet. Res."],"published-print":{"date-parts":[[2002,8]]},"abstract":"<jats:p>In this study, we compared the average coancestry and inbreeding levels for two genetic conservation schemes in which frozen semen from a gene bank is used to reduce the inbreeding in a live population. For a simple scheme in which only semen of generation-0 (G<jats:sub>0<\/jats:sub>) sires is used, the level of inbreeding asymptotes to 1\/(2<jats:italic>N<\/jats:italic>), where <jats:italic>N<\/jats:italic> is the number of newborn sires in the base generation and rate of inbreeding goes to zero. However, when only sires of G<jats:sub>0<\/jats:sub> are selected, all genes will eventually descend from the founder sires and all genes from the founder dams are lost. We propose an alternative scheme in which <jats:italic>N <\/jats:italic>sires from generation 1 (G<jats:sub>1<\/jats:sub>), as well as the <jats:italic>N<\/jats:italic> sires from G<jats:sub>0<\/jats:sub>, have semen conserved, and the semen of G<jats:sub>0<\/jats:sub> and G<jats:sub>1<\/jats:sub> sires is used for dams of odd and even generation numbers, respectively. With this scheme, the level of inbreeding asymptotes to 1\/(3<jats:italic>N<\/jats:italic>) and the genes of founder dams are also conserved, because 50% of the genes of sires of G<jats:sub>1<\/jats:sub> are derived from the founder dams. A computer simulation study shows that this is the optimum design to minimize inbreeding, even if semen from later generations is available.<\/jats:p>","DOI":"10.1017\/s0016672302005712","type":"journal-article","created":{"date-parts":[[2002,9,20]],"date-time":"2002-09-20T12:48:49Z","timestamp":1032526129000},"page":"27-30","source":"Crossref","is-referenced-by-count":33,"title":["The use of frozen semen to minimize inbreeding in small populations"],"prefix":"10.1155","volume":"80","author":[{"given":"ANNA K.","family":"SONESSON","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MIKE E.","family":"GODDARD","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"THEO H.\u00a0E.","family":"MEUWISSEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","published-online":{"date-parts":[[2002,9,16]]},"container-title":["Genetical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0016672302005712","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T22:46:25Z","timestamp":1609454785000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0016672302005712\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,8]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2002,8]]}},"alternative-id":["S0016672302005712"],"URL":"https:\/\/doi.org\/10.1017\/s0016672302005712","relation":{},"ISSN":["0016-6723","1469-5073"],"issn-type":[{"value":"0016-6723","type":"print"},{"value":"1469-5073","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,8]]}}}