{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T20:22:21Z","timestamp":1649017341257},"reference-count":10,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2008,7,31]],"date-time":"2008-07-31T00:00:00Z","timestamp":1217462400000},"content-version":"unspecified","delay-in-days":9435,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Biosoc. Sci."],"published-print":{"date-parts":[[1982,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>In this paper the genetic fitness of the two heterozygotes Hb A\/E and \u03b2-thalassaemia trait, in Calcutta, is examined in terms of their reproductive performance. It is found from fertility that the heterozygote Hb A\/E enjoys some selective advantage over the normal homozygote Hb A\/A, but the other heterozygote (\u03b2-thalassaemia trait) does not. But from overall reproductive performance (fertility and infant mortality together) it is postulated that the heterozygotes will eventually suffer from a selective disadvantage in a place like Calcutta, where malaria was eradicated about three decades ago.<\/jats:p>","DOI":"10.1017\/s0021932000014279","type":"journal-article","created":{"date-parts":[[2008,7,31]],"date-time":"2008-07-31T08:13:11Z","timestamp":1217491991000},"page":"391-396","source":"Crossref","is-referenced-by-count":0,"title":["A Study on genetic selection and haemoglobin heterozygotes: HB A\/E and \u03b2-thalassaemia trait"],"prefix":"10.1017","volume":"14","author":[{"given":"K. K.","family":"Bhattacharya","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M.","family":"Sarkar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. K.","family":"Das","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. K.","family":"Ghosh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2008,7,31]]},"reference":[{"key":"S0021932000014279_ref004","unstructured":"Deka R. (1975) Fertility and Hemoglobin Genotypes\u2014a Population Study in Upper Assam. PhD thesis, Dibrugarh University. (Cited by Flatz, 1978)."},{"key":"S0021932000014279_ref005","first-page":"189","article-title":"Hemoglobin E: distribution and population dynamics","volume":"3","author":"Flatz","year":"1967","journal-title":"Humangenetik"},{"key":"S0021932000014279_ref007","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-1809.1965.tb00511.x"},{"key":"S0021932000014279_ref002","first-page":"101","article-title":"Thalassaemia: clinical and haematological aspects","volume":"7","author":"Chatterjea","year":"1965","journal-title":"Tringle"},{"key":"S0021932000014279_ref003","volume-title":"Practical Haematology","author":"Dacie","year":"1977"},{"key":"S0021932000014279_ref008","volume-title":"Human Races","author":"Garn","year":"1961"},{"key":"S0021932000014279_ref006","first-page":"191","volume-title":"Medical Genetics in India","volume":"2","author":"Flatz","year":"1978"},{"key":"S0021932000014279_ref010","first-page":"263","volume-title":"Trends in Haematology","author":"Weatherall","year":"1975"},{"key":"S0021932000014279_ref009","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-1809.1960.tb01750.x"},{"key":"S0021932000014279_ref001","doi-asserted-by":"publisher","DOI":"10.1101\/SQB.1964.029.01.018"}],"container-title":["Journal of Biosocial Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0021932000014279","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T16:29:50Z","timestamp":1558715390000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0021932000014279\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,10]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1982,10]]}},"alternative-id":["S0021932000014279"],"URL":"https:\/\/doi.org\/10.1017\/s0021932000014279","relation":{},"ISSN":["0021-9320","1469-7599"],"issn-type":[{"value":"0021-9320","type":"print"},{"value":"1469-7599","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,10]]}}}