{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,8]],"date-time":"2026-11-08T03:32:22Z","timestamp":1794108742175,"version":"4.8.0"},"reference-count":26,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T00:00:00Z","timestamp":1243814400000},"content-version":"unspecified","delay-in-days":9982,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Dairy Research"],"published-print":{"date-parts":[[1982,2]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Experiments involving the depletion of milk calcium phosphate (MCP) with EDTA have shown that it has a Ca to phosphate ratio of 1\u00b761\u00b10\u00b704, close to that of dental enamel. The calcium phosphate also contains small amounts of citrate (citrate\/P<jats:sub>i<\/jats:sub> = 0\u00b7097\u00b10\u00b7011) and Mg (Mg\/P<jats:sub>i<\/jats:sub> = 0\u00b7044 \u00b1 0\u00b7011). These experiments and model calculations indicate that the Ca binding capacity of casein is not reduced by mineralization with calcium phosphate and hence that ion binding sites and nucleation sites are distinct, or nearly so. Calculations of the ionic equilibria in the aqueous phase of milk show that there is an invariant ion activity product for a molecular formula close to that of dicalcium phosphate. It is suggested that MCP is a mixture of salts, with dicalcium phosphate a precursor of more basic salts such as octacalcium phosphate and hydroxyapatite.<\/jats:p>","DOI":"10.1017\/s002202990002210x","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T10:59:48Z","timestamp":1244199588000},"page":"29-38","source":"Crossref","is-referenced-by-count":94,"title":["Inorganic constituents of milk III. The colloidal calcium phosphate of cow's milk"],"prefix":"10.1017","volume":"49","author":[{"given":"Carl","family":"Holt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2009,6,1]]},"reference":[{"key":"S002202990002210X_ref001","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1177\/00220345790580023901","article-title":"General comment","volume":"58","author":"Brown","year":"1979","journal-title":"Journal of Dental Research"},{"key":"S002202990002210X_ref019","doi-asserted-by":"publisher","DOI":"10.1007\/BF02010752"},{"key":"S002202990002210X_ref016","doi-asserted-by":"publisher","DOI":"10.1042\/bst0040735"},{"key":"S002202990002210X_ref004","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(62)90348-X"},{"key":"S002202990002210X_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(61)90329-0"},{"key":"S002202990002210X_ref007","doi-asserted-by":"publisher","DOI":"10.1177\/00220345790580023501"},{"key":"S002202990002210X_ref008","doi-asserted-by":"publisher","DOI":"10.1007\/BF02012795"},{"key":"S002202990002210X_ref013","doi-asserted-by":"publisher","DOI":"10.1017\/S0022029900016563"},{"key":"S002202990002210X_ref005","doi-asserted-by":"publisher","DOI":"10.1017\/S0022029900020902"},{"key":"S002202990002210X_ref015","first-page":"129","article-title":"Die submikroskopische Struktur nat\u00fcrlicher und k\u00fcnstlicher Caseinmicellen","volume":"34","author":"Knoop","year":"1979","journal-title":"Milchwissenschaft"},{"key":"S002202990002210X_ref023","doi-asserted-by":"publisher","DOI":"10.1042\/bj0280940"},{"key":"S002202990002210X_ref012","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(81)90059-2"},{"key":"S002202990002210X_ref020","doi-asserted-by":"publisher","DOI":"10.1007\/BF02010771"},{"key":"S002202990002210X_ref002","doi-asserted-by":"publisher","DOI":"10.1038\/1961050a0"},{"key":"S002202990002210X_ref022","doi-asserted-by":"publisher","DOI":"10.1017\/S0022029900020173"},{"key":"S002202990002210X_ref006","doi-asserted-by":"publisher","DOI":"10.1042\/bj1240235"},{"key":"S002202990002210X_ref010","doi-asserted-by":"publisher","DOI":"10.6028\/jres.074A.036"},{"key":"S002202990002210X_ref014","doi-asserted-by":"publisher","DOI":"10.1017\/S0022029900017295"},{"key":"S002202990002210X_ref011","doi-asserted-by":"publisher","DOI":"10.1021\/ja01079a020"},{"key":"S002202990002210X_ref017","first-page":"340","article-title":"The solubilities of hydroxyapatite at 5, 15, 25 and 37 \u00b0C.","author":"McDowell","year":"1969","journal-title":"International Association for Dental Research"},{"key":"S002202990002210X_ref009","doi-asserted-by":"publisher","DOI":"10.1007\/BF02010131"},{"key":"S002202990002210X_ref024","doi-asserted-by":"publisher","DOI":"10.1017\/S0022029900010074"},{"key":"S002202990002210X_ref025","doi-asserted-by":"publisher","DOI":"10.1126\/science.153.3743.1523"},{"key":"S002202990002210X_ref018","doi-asserted-by":"publisher","DOI":"10.1017\/S0022029900010487"},{"key":"S002202990002210X_ref026","doi-asserted-by":"publisher","DOI":"10.1017\/S0022029900009249"},{"key":"S002202990002210X_ref021","doi-asserted-by":"publisher","DOI":"10.2136\/sssaj1960.03615995002400020010x"}],"container-title":["Journal of Dairy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S002202990002210X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T21:46:20Z","timestamp":1558734380000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S002202990002210X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,2]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1982,2]]}},"alternative-id":["S002202990002210X"],"URL":"https:\/\/doi.org\/10.1017\/s002202990002210x","relation":{},"ISSN":["0022-0299","1469-7629"],"issn-type":[{"value":"0022-0299","type":"print"},{"value":"1469-7629","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,2]]}}}