{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T22:11:29Z","timestamp":1778105489765,"version":"3.51.4"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[1997,5,1]],"date-time":"1997-05-01T00:00:00Z","timestamp":862444800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Dairy Research"],"published-print":{"date-parts":[[1997,5]]},"abstract":"<jats:p>The susceptibility to penicillin-G of <jats:italic>Staphylococcus \naureus<\/jats:italic> strains that \ncause mastitis was tested in milk and in Iso-sensitest broth (ISB). The\n minimal \ninhibitory concentrations (<jats:italic>MIC<\/jats:italic>) of \u03b2-lactamase-positive \nstrains in milk were 10\u2013100-fold those in ISB, whereas the \n<jats:italic>MIC<\/jats:italic> of \u03b2-lactamase-negative strains in milk were some \n10-fold those in ISB; \u03b2-lactamase production was induced by \nmilk in \u03b2-lactamase-positive strains. Much of the increase in \nresistance to penicillin-G caused by milk can \nbe attributed to milk fat globules; the increase in resistance was related\n to the \nbinding capacity of the bacteria to milk fat globules as well as to capsule\n formation \nby the bacteria. It appears that the binding of the staphylococci to the\n fat globules \nand bacterial capsule formation resulted in a biofilm type of \ngrowth. In this case, the \nstaphylococci behaved differently from the planktonic type of growth in\n artificial \nbroth medium in which antibiotic susceptibility testing is usually carried\n out.<\/jats:p>","DOI":"10.1017\/s0022029996002026","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T13:44:43Z","timestamp":1027777483000},"page":"253-260","source":"Crossref","is-referenced-by-count":19,"title":["Binding of <i>Staphylococcus aureus<\/i> to milk fat globules increases\n \nresistance to penicillin-G"],"prefix":"10.1017","volume":"64","author":[{"given":"TERHI","family":"ALI-VEHMAS","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PETER","family":"WESTPHALEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"VESA","family":"MYLLYS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MARKUS","family":"SANDHOLM","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[1997,5,1]]},"container-title":["Journal of Dairy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022029996002026","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,11]],"date-time":"2019-05-11T20:59:26Z","timestamp":1557608366000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022029996002026\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,5]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1997,5]]}},"alternative-id":["S0022029996002026"],"URL":"https:\/\/doi.org\/10.1017\/s0022029996002026","relation":{},"ISSN":["0022-0299","1469-7629"],"issn-type":[{"value":"0022-0299","type":"print"},{"value":"1469-7629","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,5]]}}}