{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T10:18:23Z","timestamp":1762251503500},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T00:00:00Z","timestamp":1244160000000},"content-version":"unspecified","delay-in-days":11144,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[1978,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>The results of a vaccination trial in lambs with gamma-irradiated infective larvae of<jats:italic>Gaigeria pachyscelis<\/jats:italic>are described. A single percutaneous (P\/C) vaccination of lambs with 2000 infective larvae irradiated at 40 Kr induced the development of resistance. The vaccinated lambs successfully resisted a lethal challenge infection of 5000 non-irradiated larvae 3 months later. In the vaccinated lambs, the manifestations of resistance were shown by marked reduction in the worm establishment, development of retarded and functionally sterile worms and absence of clinical signs of hookworm disease after the challenge infection.<\/jats:p>","DOI":"10.1017\/s0022149x00005502","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T15:34:22Z","timestamp":1244216062000},"page":"287-290","source":"Crossref","is-referenced-by-count":3,"title":["The use of gamma-radiation-attenuated larvae of<i>Gaigeria pachyscelis<\/i>Railliet and Henry, 1910, for vaccination in lambs"],"prefix":"10.1017","volume":"52","author":[{"given":"Md. Zafrullah","family":"Ansari","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunwar Suresh","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,6,5]]},"reference":[{"key":"S0022149X00005502_ref007","first-page":"845","article-title":"Effect of X-rays on trichinae","volume":"20","author":"Schwartz","year":"1921","journal-title":"Journal of Agricultural Research"},{"key":"S0022149X00005502_ref003","first-page":"1329","article-title":"The natural history of parasitic bronchitis with notes on prophylaxis and treatment","volume":"69","author":"Jarrett","year":"1957","journal-title":"Veterinary Record"},{"key":"S0022149X00005502_ref006","first-page":"1239","article-title":"Canine hookworm vaccine","volume":"156","author":"Miller","year":"1970","journal-title":"Journal of American Veterinary Medical Association"},{"key":"S0022149X00005502_ref005","doi-asserted-by":"publisher","DOI":"10.2307\/3276194"},{"key":"S0022149X00005502_ref001","doi-asserted-by":"publisher","DOI":"10.2307\/3273259"},{"key":"S0022149X00005502_ref002","first-page":"407","article-title":"The production of active immunity against the canine hookworm, Uncinaria stenocephala","volume":"135","author":"Dow","year":"1959","journal-title":"Journal of American Veterinary Medical Association"},{"key":"S0022149X00005502_ref011","first-page":"87","article-title":"Helminth immunity","volume":"7","author":"Urquhart","year":"1962","journal-title":"Advances in Veterinary Science"},{"key":"S0022149X00005502_ref009","first-page":"212","article-title":"Vaccination against Dictyocaulus filaria with irradiated larvae","volume":"121","author":"Sokolic","year":"1965","journal-title":"British Veterinary Journal"},{"key":"S0022149X00005502_ref010","first-page":"32","article-title":"Studies on radiation attenuated helminth vaccines; laboratory studies on the production and evaluation of gamma-irradiated vaccine against the sheep lungworm, Dictyocaulus filaria","volume":"42","author":"Tewari","year":"1972","journal-title":"Indian Journal of Animal Sciences"},{"key":"S0022149X00005502_ref004","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1177\/003591575805100912","article-title":"Irradiated helminth larvae in vaccination","volume":"51","author":"Jarrett","year":"1958","journal-title":"Proceedings of Royal Society of Medicine"},{"key":"S0022149X00005502_ref008","doi-asserted-by":"publisher","DOI":"10.2307\/3275768"}],"container-title":["Journal of Helminthology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022149X00005502","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T06:59:39Z","timestamp":1589871579000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022149X00005502\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,12]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1978,12]]}},"alternative-id":["S0022149X00005502"],"URL":"https:\/\/doi.org\/10.1017\/s0022149x00005502","relation":{},"ISSN":["0022-149X","1475-2697"],"issn-type":[{"value":"0022-149X","type":"print"},{"value":"1475-2697","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,12]]}}}