{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T22:56:04Z","timestamp":1763765764942},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T00:00:00Z","timestamp":1244160000000},"content-version":"unspecified","delay-in-days":10596,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[1980,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Observations on the course of <jats:italic>Hymenolepis nana<\/jats:italic> infection in immunosuppressed mice are presented. Treatment of the host with hydrocortisone acetate caused superinfection of the bowel with worms and the development of normal cysticercoids in the mesenteric lymph node and liver. Natural infection of mice deprived of their T-cells by pre-adult thymectomy and administration of antithymocyte serum resulted in superinfection and widespread metastasis of aberrant cysticercoids that were greatly enlarged and without scolices, causing death after about five months. The significance of these findings and their possible relevance to human infection with <jats:italic>H. nana<\/jats:italic> are discussed.<\/jats:p>","DOI":"10.1017\/s0022149x00006386","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T11:33:22Z","timestamp":1244201602000},"page":"75-82","source":"Crossref","is-referenced-by-count":25,"title":["Abnormal development of <i>Hymenolepis nana<\/i> larvae in immunosuppressed mice"],"prefix":"10.1017","volume":"54","author":[{"given":"S. B.","family":"Lucas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Hassounah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Muller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. J.","family":"Doenhoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,6,5]]},"reference":[{"key":"S0022149X00006386_ref001","first-page":"47","article-title":"Findings in the contents of the terminal ileum obtained by Miller-Abbott probe in a human case of Hymenolepis nana infection","volume":"18","author":"Alonso","year":"1966","journal-title":"Revista Cubana Medicina Tropical"},{"key":"S0022149X00006386_ref017","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7998.1954.tb07794.x"},{"key":"S0022149X00006386_ref010","first-page":"960","volume-title":"Pathology of Protozoal and Helminthic Diseases","author":"Garner","year":"1971"},{"key":"S0022149X00006386_ref018","first-page":"591","article-title":"Effect of cortisone on acquired resistance to Hymenolepis nana in mice","volume":"18","author":"Okamoto","year":"1969","journal-title":"Japanese Journal of Parasitology"},{"key":"S0022149X00006386_ref006","first-page":"65","article-title":"Disseminated parasitosis in an immunosuppressed patient","volume":"100","author":"Connor","year":"1976","journal-title":"Archives of Pathology and Laboratory Medicine"},{"key":"S0022149X00006386_ref008","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(70)90116-5"},{"key":"S0022149X00006386_ref015","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1966.tb12849.x"},{"key":"S0022149X00006386_ref007","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(69)90083-6"},{"key":"S0022149X00006386_ref011","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1962.11.46"},{"key":"S0022149X00006386_ref003","first-page":"149","article-title":"New data on migration of eggs and larval stages of Hymenolepis nana (Siebold, 1852) in white mice","volume":"35","author":"Astafiev","year":"1966","journal-title":"Meditsinskya Parazitologiya i Parazitarnye Bolezni"},{"key":"S0022149X00006386_ref014","first-page":"1461","article-title":"Reversal of the thymus dependent influence in radiation leukaemogenesis of C57B1 mice","volume":"31","author":"Law","year":"1963","journal-title":"Journal of the National Cancer Institute."},{"key":"S0022149X00006386_ref009","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1979.28.260"},{"key":"S0022149X00006386_ref002","first-page":"93","article-title":"On the possibility of development of Hymenolepis nana (Siebold, 1852) in mesenteric lymph nodes of white mice","volume":"35","author":"Astafiev","year":"1966","journal-title":"Meditsinskya Parazitologiya i Parazitarnye Bolezni"},{"key":"S0022149X00006386_ref020","first-page":"111","article-title":"Hymenolepis nana embedded in a retroperitoneal sarcoma of a white rat","volume":"15","author":"Perez-Arroyo","year":"1977","journal-title":"Patologia"},{"key":"S0022149X00006386_ref004","first-page":"299","article-title":"Gemmation of tissue larvae of Hymenolepis nana","volume":"39","author":"Astafiev","year":"1970","journal-title":"Meditsinskya Parazitologiya i Parazitarnye Bolezni"},{"key":"S0022149X00006386_ref005","doi-asserted-by":"publisher","DOI":"10.1007\/BF00418205"},{"key":"S0022149X00006386_ref013","doi-asserted-by":"publisher","DOI":"10.1159\/000231964"},{"key":"S0022149X00006386_ref016","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(79)92859-9"},{"key":"S0022149X00006386_ref021","first-page":"57","article-title":"Proceedings of the Helminthological Society of Washington","volume":"17","author":"Price","year":"1930","journal-title":"Journal of Parasitology"},{"key":"S0022149X00006386_ref019","doi-asserted-by":"publisher","DOI":"10.2307\/3275272"},{"key":"S0022149X00006386_ref012","first-page":"414","article-title":"Studies on Hymenolepis fraterna","volume":"22","author":"Hunninen","year":"1935","journal-title":"American Journal of Hygiene"}],"container-title":["Journal of Helminthology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022149X00006386","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,26]],"date-time":"2019-05-26T15:10:10Z","timestamp":1558883410000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022149X00006386\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,6]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1980,6]]}},"alternative-id":["S0022149X00006386"],"URL":"https:\/\/doi.org\/10.1017\/s0022149x00006386","relation":{},"ISSN":["0022-149X","1475-2697"],"issn-type":[{"value":"0022-149X","type":"print"},{"value":"1475-2697","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,6]]}}}