{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T18:05:39Z","timestamp":1648836339298},"reference-count":10,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T00:00:00Z","timestamp":1244160000000},"content-version":"unspecified","delay-in-days":11784,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[1977,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>The present investigation has shown that combined treatment with dexamethasone and prednisolone or with hydrocortisone and dexamethasone enhances the susceptibility of albino rats to <jats:italic>Paragonimus miyazakii<\/jats:italic>, presumably by suppressing the host\u2019s immune responses. In the rats given these combined treatments, the size and egg production of worms were markedly increased. Use of dexamethasone or prednisolone alone had relatively little influence on the growth and maturity of <jats:italic>P. miyazakii<\/jats:italic>. In serological analysis and agar double diffusion, considerable differences were recognized between the gamma-globulin fractions and antigen-antibody systems (Precipitin bands) of the treated groups and the untreated group. The mechanism of action of these immunosuppressants in this system remains obscure.<\/jats:p>","DOI":"10.1017\/s0022149x0000729x","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T15:38:06Z","timestamp":1244216286000},"page":"87-94","source":"Crossref","is-referenced-by-count":4,"title":["Influence of immunosuppressants on the establishment of <i>Paragonimus miyazakii<\/i> in albino rats"],"prefix":"10.1017","volume":"51","author":[{"given":"Y.","family":"Hashiguchi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Hirai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,6,5]]},"reference":[{"key":"S0022149X0000729X_ref008","doi-asserted-by":"publisher","DOI":"10.2307\/3276578"},{"key":"S0022149X0000729X_ref007","first-page":"51","article-title":"The effect of worm burden and cortisone on the Paragonimus infection in albino rats","volume":"16","author":"Tada","year":"1967","journal-title":"Japanese Journal of Parasitology"},{"key":"S0022149X0000729X_ref006","doi-asserted-by":"publisher","DOI":"10.2307\/3276499"},{"key":"S0022149X0000729X_ref004","first-page":"335","article-title":"Size differences of Paragonimus miyazakii adults parasitic in various host animals","volume":"15","author":"Kamo","year":"1966","journal-title":"Japanese Journal of Parasitology"},{"key":"S0022149X0000729X_ref003","first-page":"128","article-title":"Studies on schistosomiasis. II. Summary of further studies on methods of recovering eggs of Schistosoma Japonicum from stools","volume":"8","author":"Hunter","year":"1948","journal-title":"United States Army Medical Sept. Bulletin"},{"key":"S0022149X0000729X_ref005","first-page":"17","article-title":"Electrophoretic studies of the sera of white rats and cats following infection with Paragonimus Kellicotti Ward, 1908","volume":"45","author":"Kruidenier","year":"1959","journal-title":"Journal of Parasitology"},{"key":"S0022149X0000729X_ref001","first-page":"27","article-title":"Biological studies on the host-parasite relationships between the lung flukes, Paragonimus spp., and some murine mammals","volume":"22","author":"Hashiguchi","year":"1973","journal-title":"Research Reports of the Kochi University, Natural Science"},{"key":"S0022149X0000729X_ref010","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1965.14.586"},{"key":"S0022149X0000729X_ref009","first-page":"34","article-title":"Comparative studies on Paragonimus miyazakii and P. ohirai infections in albino rats","volume":"18","author":"Tada","year":"1969","journal-title":"Japanese Journal of Parasitology"},{"key":"S0022149X0000729X_ref002","first-page":"181","article-title":"Studies on the distribution of Paragonimus miyazakii in Shikoku, Japan. 1. Distribution of P. miyazakii in the southern part of Shikoku","volume":"23","author":"Hashiguchi","year":"1974","journal-title":"Japanese Journal of Parasitology"}],"container-title":["Journal of Helminthology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022149X0000729X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T19:21:59Z","timestamp":1559071319000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022149X0000729X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,3]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1977,3]]}},"alternative-id":["S0022149X0000729X"],"URL":"https:\/\/doi.org\/10.1017\/s0022149x0000729x","relation":{},"ISSN":["0022-149X","1475-2697"],"issn-type":[{"value":"0022-149X","type":"print"},{"value":"1475-2697","type":"electronic"}],"subject":[],"published":{"date-parts":[[1977,3]]}}}