{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T08:38:12Z","timestamp":1648975092946},"reference-count":10,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T00:00:00Z","timestamp":1244160000000},"content-version":"unspecified","delay-in-days":9593,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[1983,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The activity, in terms of speed of action, of three anticestode drugs against <jats:italic>Hymenolepis nana<\/jats:italic>, both <jats:italic>in vivo<\/jats:italic> and <jats:italic>in vitro<\/jats:italic>, was investigated. Praziquantel was most effective <jats:italic>in vivo<\/jats:italic>, but had little action on adult worms and cysticercoids <jats:italic>in vitro<\/jats:italic>. Niclosamide, the least effective <jats:italic>in vivo<\/jats:italic>, was highly toxic <jats:italic>in vitro<\/jats:italic>. Compound 77\u20136 killed adult worms and cysticercoids <jats:italic>in vitro<\/jats:italic> in 10 min and 15 min respectively at 1000 \u03bcg\/ml of drug concentration, but its <jats:italic>in viro<\/jats:italic> effect was intermediate between that of praziquantel and niclosamide.<\/jats:p>","DOI":"10.1017\/s0022149x00007847","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T15:30:32Z","timestamp":1244215832000},"page":"31-36","source":"Crossref","is-referenced-by-count":4,"title":["Comparative activity of anticestode drugs\u2014praziquantel, niclosamide and Compound 77\u20136, against <i>Hymenolepis nana<\/i>"],"prefix":"10.1017","volume":"57","author":[{"given":"Suman","family":"Gupta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. C.","family":"Katiyar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,6,5]]},"reference":[{"key":"S0022149X00007847_ref003","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1962.11.46"},{"key":"S0022149X00007847_ref009","unstructured":"Thomas H. , G\u00f6Nnert R. , Pohlke G. & Seubert J. (1975 a) Investigations about treatment of larval cestodes. 7th International Conference on Pathophysiology of Parasitic Infections, Thessaloniki."},{"key":"S0022149X00007847_ref010","unstructured":"Thomas H. , G\u00f6nnert R. , Pohlke R. & Seubert J. (1975 b) A new compound against adult tapeworms. 7th International Conference on Pathophysiology of Parasitic Infections, Thessaloniki."},{"key":"S0022149X00007847_ref006","doi-asserted-by":"publisher","DOI":"10.1002\/ps.2780080521"},{"key":"S0022149X00007847_ref007","doi-asserted-by":"publisher","DOI":"10.1007\/BF00389898"},{"key":"S0022149X00007847_ref001","first-page":"391","article-title":"The effect of praziquantel on Hymenolepis diminuta in vitro","volume":"30","author":"Andrews","year":"1979","journal-title":"Tropenmedizin und Parasitologie"},{"key":"S0022149X00007847_ref002","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X00006751"},{"key":"S0022149X00007847_ref004","first-page":"697","article-title":"Search for compounds effective against Hymenolepis nana larvae","volume":"43","author":"Krotov","year":"1974","journal-title":"Meditsinkaya Parazitologiya i Parazitarnye Bolezni"},{"key":"S0022149X00007847_ref005","first-page":"436","article-title":"Screening of cestodicidal compounds on a tapeworm Hymenolepis nana in vitro","volume":"15","author":"Sen","year":"1960","journal-title":"British Journal of Pharmacology"},{"key":"S0022149X00007847_ref008","doi-asserted-by":"publisher","DOI":"10.1007\/BF00384831"}],"container-title":["Journal of Helminthology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022149X00007847","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T19:32:45Z","timestamp":1558726365000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022149X00007847\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,3]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1983,3]]}},"alternative-id":["S0022149X00007847"],"URL":"https:\/\/doi.org\/10.1017\/s0022149x00007847","relation":{},"ISSN":["0022-149X","1475-2697"],"issn-type":[{"value":"0022-149X","type":"print"},{"value":"1475-2697","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,3]]}}}