{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T03:07:25Z","timestamp":1712891245022},"reference-count":23,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T00:00:00Z","timestamp":1244160000000},"content-version":"unspecified","delay-in-days":8222,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[1986,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>The kinetics of the lymphoblast response in mice during the course of a primary infection with <jats:italic>Hymenolepis nana<\/jats:italic> was measured by the <jats:italic>in vivo<\/jats:italic> uptake of <jats:sup>125<\/jats:sup>IUdR. The response was most marked in tissues local to the site of infection, involving to nodes draining the small intestine but not other areas, e.g., inguinal lymph nodes. A close correlation between these responses and the course of inflection was observed. Uptake of <jats:sup>125<\/jats:sup>IUdR was greatest in the mesenteric lymph node (MLN) but the peak reached in this organ was later than that in Peyer's patches (PP), small intestine (SI) and spleen (S). The increase in lymphoblast activity of the MLN was similar with <jats:italic>Trichinella spiralis<\/jats:italic>; no significant blast cell response to inflection with <jats:italic>H. diminuta<\/jats:italic> was found till day 9 after injection, the results being similar to those obtained when <jats:italic>H. nana<\/jats:italic> inflections were established using cysticercoids rather than eggs. It has been shown that the increase in lymphoblast activity was closely correlated with the presence of cells which are most effective in adoptive transfer immunity. A dose-dependent effect was detected in blast cell activity of MLN in different inflection levels with <jats:italic>T. spiralis<\/jats:italic> and <jats:italic>H. nana<\/jats:italic>.<\/jats:p>","DOI":"10.1017\/s0022149x00008555","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T15:23:11Z","timestamp":1244215391000},"page":"313-321","source":"Crossref","is-referenced-by-count":6,"title":["Blast cell activity in mice inflected with <i>Hymenolepis nana, H. diminuta<\/i> and <i>Trichinella spiralis<\/i>: <i>in vivo<\/i> uptake of <sup>125<\/sup>IUdR in lymphoid tissues and gut"],"prefix":"10.1017","volume":"60","author":[{"given":"F.","family":"Gabriele","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. R.","family":"Ecca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Wakelin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Palmas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,6,5]]},"reference":[{"key":"S0022149X00008555_ref019","first-page":"723","article-title":"Migration of lymphoblasts to the small intestine. I. Effect of Trichinella spiralis inflection on the migration of mesenteric lymphoblasts and mesenteric T lymphoblasts in syngeneic mice","volume":"31","author":"Rose","year":"1976","journal-title":"Immunology"},{"key":"S0022149X00008555_ref018","first-page":"571","article-title":"Selective migration of lymphocytes within the mouse small intestine","volume":"26","author":"Parrotti","year":"1974","journal-title":"Immunology"},{"key":"S0022149X00008555_ref014","first-page":"794","volume-title":"Progress in Immunology","volume":"4","author":"Mitchell","year":"1980"},{"key":"S0022149X00008555_ref001","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1017\/S0031182000150176","article-title":"Immunity to adult cestodes","volume":"82","author":"Andreassen","year":"1981","journal-title":"Parasitology"},{"key":"S0022149X00008555_ref004","first-page":"303","volume-title":"Ecological aspects of Parasitology","author":"Befus","year":"1976"},{"key":"S0022149X00008555_ref015","first-page":"93","article-title":"Immunity in the parasitic relationship between helminths and hosts","volume":"17","author":"Ogilvie","year":"1973","journal-title":"Progress in Allergy"},{"key":"S0022149X00008555_ref005","first-page":"197","article-title":"The physiology of the local innune response and the gastrointestinal tract","volume":"4","author":"Bienenstock","year":"1964","journal-title":"progress in Immunology II"},{"key":"S0022149X00008555_ref008","doi-asserted-by":"publisher","DOI":"10.1080\/11250008009440334"},{"key":"S0022149X00008555_ref010","first-page":"443","article-title":"Short lived, dividing cells mediate adoptive transfer of immunity to Trichinella spiralis in mice. I. Availability of cells in primary and secondary inflections in relation to cellular changes in the mesenteric lymph-node","volume":"46","author":"Grenics","year":"1982","journal-title":"Immunology"},{"key":"S0022149X00008555_ref007","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(74)90003-4"},{"key":"S0022149X00008555_ref023","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000047843"},{"key":"S0022149X00008555_ref006","first-page":"671","article-title":"The cellular transfer of immunity to Trichostrongylus colubriformis in an isogenic strain of guinea-pig. IV. The localization of immnue lymphocytes in small intestine in inflected and non-inflected guinea-pigs","volume":"15","author":"Dineen","year":"1968","journal-title":"Immunology"},{"key":"S0022149X00008555_ref002","first-page":"391","article-title":"Passive protection of node mice with lymphocytes from mice inflected with Hymenolepis nana eggs","volume":"31","author":"Asano","year":"1982","journal-title":"Japanese Journal of Parasitology"},{"key":"S0022149X00008555_ref013","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830090118"},{"key":"S0022149X00008555_ref009","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(84)90007-9"},{"key":"S0022149X00008555_ref016","first-page":"147","article-title":"Cooperation between antobodies and cells in immunity to a namatode parasite","volume":"19","author":"Ogilvie","year":"1974","journal-title":"Transplantation Review"},{"key":"S0022149X00008555_ref012","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-308X(08)60321-8"},{"key":"S0022149X00008555_ref003","first-page":"901","article-title":"Immediate IgA precursor cells in rabbit intestinal lamina propria","volume":"35","author":"Befus","year":"1978","journal-title":"Immunology"},{"key":"S0022149X00008555_ref020","first-page":"57","volume-title":"Cell-mediated immunity responses in parasitic inflections","author":"Soulsby","year":"1972"},{"key":"S0022149X00008555_ref022","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000049507"},{"key":"S0022149X00008555_ref017","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000001311"},{"key":"S0022149X00008555_ref011","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000045479"},{"key":"S0022149X00008555_ref021","first-page":"451","article-title":"Short lived, dividing cells mediate adoptive transfer of immunity to Trichonella spiralis in mice. II. In vivo characteristics of the cells","volume":"46","author":"Wakelin","year":"1982","journal-title":"Immunology"}],"container-title":["Journal of Helminthology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022149X00008555","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T03:00:20Z","timestamp":1558494020000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022149X00008555\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,12]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1986,12]]}},"alternative-id":["S0022149X00008555"],"URL":"https:\/\/doi.org\/10.1017\/s0022149x00008555","relation":{},"ISSN":["0022-149X","1475-2697"],"issn-type":[{"value":"0022-149X","type":"print"},{"value":"1475-2697","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,12]]}}}