{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T21:14:49Z","timestamp":1769375689607,"version":"3.49.0"},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T00:00:00Z","timestamp":1244160000000},"content-version":"unspecified","delay-in-days":7582,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[1988,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>The laboratory study of dracunculiasis has suffered from the lack of a suitable, readily available animal model. We have been able to experimentally infect ferrets,<jats:italic>Mustela putorius furo<\/jats:italic>, with the North American dracunculid,<jats:italic>Dracunculus insignis<\/jats:italic>. Ferrets were inoculated with 75 to 100 infective larvae and were necropsied 90 to 240 days later. Guinea worms were recovered from 10 (56%) of 18 ferrets. A total of 44 worms were recovered, for an average of 4.4 worms per infected ferret. Gravid female worms were recovered as early as 128 days postinoculation. Thirteen (87%) of 15 gravid female worms were recovered from the extremities. Living male worms were recovered at 200 days of age, indicating that not all male worms die shortly after mating. First-stage larvae recovered from gravid females as early as 200 days of age were found to be infective to the copepod.<jats:italic>Acanthocyclops vernalis<\/jats:italic>. These observations suggest that the ferret is an excellent laboratory animal for dracunculiasis research.<\/jats:p>","DOI":"10.1017\/s0022149x00011640","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T15:20:19Z","timestamp":1244215219000},"page":"265-270","source":"Crossref","is-referenced-by-count":19,"title":["<i>Dracunculus insignis<\/i>: experimental infection in the ferret,<i>Mustela putorius furo<\/i>"],"prefix":"10.1017","volume":"62","author":[{"given":"M. L.","family":"Eberhard","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Ruiz-Tiben","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. V.","family":"Wallace","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,6,5]]},"reference":[{"key":"S0022149X00011640_ref009","doi-asserted-by":"publisher","DOI":"10.1038\/226662a0"},{"key":"S0022149X00011640_ref005","doi-asserted-by":"publisher","DOI":"10.2307\/3280490"},{"key":"S0022149X00011640_ref002","doi-asserted-by":"publisher","DOI":"10.1139\/z74-019"},{"key":"S0022149X00011640_ref001","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1976.25.704"},{"key":"S0022149X00011640_ref004","first-page":"1","article-title":"Dracontiasis in Ohio carnivores and reptiles with a discussion of the dracunculid taxonomic problem. (Nematoda: Dracunculidae)","volume":"63","author":"Crites","year":"1963","journal-title":"Ohio Journal of Science"},{"key":"S0022149X00011640_ref010","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1017\/S0022149X00007161","article-title":"Studies on Dracunculus medinensis (Linnaeus). II. Effects of acidity on the infective larvae","volume":"45","author":"Muller","year":"1971","journal-title":"Journal of Helminthology"},{"key":"S0022149X00011640_ref007","doi-asserted-by":"publisher","DOI":"10.2307\/3223715"},{"key":"S0022149X00011640_ref003","doi-asserted-by":"publisher","DOI":"10.1139\/z75-014"},{"key":"S0022149X00011640_ref011","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000044681"},{"key":"S0022149X00011640_ref008","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X00017934"},{"key":"S0022149X00011640_ref006","first-page":"298","article-title":"Compendium of recent literature on the ferret","volume":"35","author":"Frederick","year":"1985","journal-title":"Laboratory Animal Science"}],"container-title":["Journal of Helminthology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022149X00011640","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T06:56:37Z","timestamp":1589871397000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022149X00011640\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,9]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1988,9]]}},"alternative-id":["S0022149X00011640"],"URL":"https:\/\/doi.org\/10.1017\/s0022149x00011640","relation":{},"ISSN":["0022-149X","1475-2697"],"issn-type":[{"value":"0022-149X","type":"print"},{"value":"1475-2697","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,9]]}}}