{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T09:43:21Z","timestamp":1710409401842},"reference-count":25,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,11,18]],"date-time":"2009-11-18T00:00:00Z","timestamp":1258502400000},"content-version":"unspecified","delay-in-days":9393,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[1984,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Elevated serum lipids are associated with infections of laboratory rodents with plerocercoids of<jats:italic>Spirometra mansonoides<\/jats:italic>. The effect of infection with these larval tapeworms on triglyceride degradation and hepatic<jats:italic>de novo<\/jats:italic>fatty acid synthesis was investigated in Syrian hamsters. Serum lipoprotein electrophoresis revealed a consistent elevation in very low density lipoproteins in the infected animals. Lipoprotein lipase activity was enhanced in the infected animals. After seven days of plerocercoid infection the activity of acetyl-CoA carboxylase (E.C. 6.4.1.2) was significantly elevated after 6,12 and 18 hours of fasting. Fatty acid synthetase was significantly increased after 0,6,12,18 and 24 hours of fasting. Therefore, a chronic insulin-like activity on lipid metabolism of hamsters is associated with plerocercoid infection.<\/jats:p>","DOI":"10.1017\/s0022149x00028017","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T15:29:23Z","timestamp":1244215763000},"page":"25-30","source":"Crossref","is-referenced-by-count":4,"title":["Insulin-like effects of fatty acid synthesis in liver of hamsters infected with plerocercoids of the tapeworm,<i>Spirometra mansonoides<\/i>"],"prefix":"10.1017","volume":"58","author":[{"given":"C. Kirk","family":"Phares","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. M.","family":"Carroll","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,11,18]]},"reference":[{"key":"S0022149X00028017_ref018","doi-asserted-by":"publisher","DOI":"10.2307\/3279573"},{"key":"S0022149X00028017_ref015","doi-asserted-by":"publisher","DOI":"10.2307\/3276304"},{"key":"S0022149X00028017_ref002","doi-asserted-by":"publisher","DOI":"10.2337\/diab.28.9.828"},{"key":"S0022149X00028017_ref007","doi-asserted-by":"publisher","DOI":"10.2307\/3276704"},{"key":"S0022149X00028017_ref014","first-page":"143","article-title":"Stimulation of lipogenesis in hamsters by Spirometra mansonoides","volume":"51","author":"Meyer","year":"1965","journal-title":"Journal of Parasitology"},{"key":"S0022149X00028017_ref011","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"Journal of Biological Chemistry"},{"key":"S0022149X00028017_ref025","doi-asserted-by":"crossref","first-page":"6644","DOI":"10.1016\/S0021-9258(18)50417-8","article-title":"Regulation of hepatic acctyl cocnzyme a carboxylase by insulin and glucagon","volume":"254","author":"Witters","year":"1979","journal-title":"Journal of Biological Chemistry"},{"key":"S0022149X00028017_ref019","doi-asserted-by":"publisher","DOI":"10.2307\/3279768"},{"key":"S0022149X00028017_ref012","first-page":"123","volume-title":"Endocrinology 1, Grune and Stratton","author":"Merimee","year":"1979"},{"key":"S0022149X00028017_ref017","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-152808-9.50012-2"},{"key":"S0022149X00028017_ref013","doi-asserted-by":"publisher","DOI":"10.1016\/0026-0495(73)90211-4"},{"key":"S0022149X00028017_ref023","first-page":"97","article-title":"Biological properties of the growth hormone-like factor from the pleroccrcoid of Spirometra mansonoides","volume":"27","author":"Steelman","year":"1971","journal-title":"Recent Progress in Hormone Research"},{"key":"S0022149X00028017_ref010","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/9780470110232.ch5","volume-title":"Methods of Biochemical Analysis","author":"Korn","year":"1959"},{"key":"S0022149X00028017_ref009","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1016\/S0021-9258(19)44292-0","article-title":"The regulation of fatty acid biosynthesis in human skin fibroblasts","volume":"248","author":"Jacobs","year":"1973","journal-title":"Journal of Biological Chemistry"},{"key":"S0022149X00028017_ref001","doi-asserted-by":"publisher","DOI":"10.2337\/diab.17.3.127"},{"key":"S0022149X00028017_ref003","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1092695"},{"key":"S0022149X00028017_ref004","doi-asserted-by":"publisher","DOI":"10.1210\/endo-88-4-924"},{"key":"S0022149X00028017_ref006","doi-asserted-by":"publisher","DOI":"10.2307\/3280472"},{"key":"S0022149X00028017_ref008","first-page":"33","volume-title":"Methods in Enzymology","author":"Hsu","year":"1969"},{"key":"S0022149X00028017_ref016","doi-asserted-by":"publisher","DOI":"10.2307\/3278670"},{"key":"S0022149X00028017_ref020","doi-asserted-by":"publisher","DOI":"10.1016\/0166-6851(80)90046-8"},{"key":"S0022149X00028017_ref021","doi-asserted-by":"publisher","DOI":"10.2307\/3276221"},{"key":"S0022149X00028017_ref022","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1093\/clinchem\/19.4.419","article-title":"Colorimetric microdetermination of free fatty acids","volume":"19","author":"Soloni","year":"1973","journal-title":"Clinical Chemistry"},{"key":"S0022149X00028017_ref005","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(60)90169-8"},{"key":"S0022149X00028017_ref024","first-page":"259","article-title":"The somatomedins: a family of insulin-like hormones under growth hormone control","volume":"30","author":"Vanwyk","year":"1974","journal-title":"Recent Progress in Hormone Research"}],"container-title":["Journal of Helminthology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022149X00028017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T09:10:35Z","timestamp":1710407435000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022149X00028017\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,3]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1984,3]]}},"alternative-id":["S0022149X00028017"],"URL":"https:\/\/doi.org\/10.1017\/s0022149x00028017","relation":{},"ISSN":["0022-149X","1475-2697"],"issn-type":[{"value":"0022-149X","type":"print"},{"value":"1475-2697","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,3]]}}}