{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T01:37:11Z","timestamp":1750469831769},"reference-count":3,"publisher":"Cambridge University Press (CUP)","issue":"1-2","license":[{"start":{"date-parts":[[2009,11,18]],"date-time":"2009-11-18T00:00:00Z","timestamp":1258502400000},"content-version":"unspecified","delay-in-days":16606,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[1964,6]]},"abstract":"<jats:p>It was possible to make a more critical study of immunity against <jats:italic>A. suum<\/jats:italic> by infecting pathogen-free, colostrum-deprived pigs produced by hysterectomy.<\/jats:p><jats:p>By means of the conglutinating complement absorption test, using a saline extract of worm as antigen, antibodies were first demonstrated in the circulation of three experimentally-infected pigs between the 10th and 13th days of infection, and were detected in the sera of two of them for at least 97 days.<\/jats:p><jats:p>The infections did not become patent, and no acquired immunity was shown by the pigs against a reinfection 97 days later. There was no evidence of an age immunity against migrant larvae.<\/jats:p><jats:p>A rise in serum antibody was observed, within seven days of infection, in six pigs aged between 10 weeks and 11 months, following a test dose of 500,000 eggs. Three suckling pigs, aged three weeks, did not respond serologically within seven days to the same test dose.<\/jats:p>","DOI":"10.1017\/s0022149x00033691","type":"journal-article","created":{"date-parts":[[2009,11,18]],"date-time":"2009-11-18T21:15:13Z","timestamp":1258578913000},"page":"151-158","source":"Crossref","is-referenced-by-count":3,"title":["Immunological Studies on Experimental Infection of Pigs with <i>Ascaris suum<\/i> Goeze, 1782. IV. The Primary Antibody Response"],"prefix":"10.1017","volume":"38","author":[{"given":"L. F.","family":"Taffs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,11,18]]},"reference":[{"key":"S0022149X00033691_ref002","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X00019970"},{"key":"S0022149X00033691_ref003","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X0003368X"},{"key":"S0022149X00033691_ref001","first-page":"461","article-title":"The production by hysterectomy of pathogen-free, colostrum-deprived pigs and the foundation of a minimal-disease herd","volume":"72","author":"Betts","year":"1960","journal-title":"Vet. Rec."}],"container-title":["Journal of Helminthology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022149X00033691","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,3]],"date-time":"2019-06-03T20:23:57Z","timestamp":1559593437000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022149X00033691\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1964,6]]},"references-count":3,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[1964,6]]}},"alternative-id":["S0022149X00033691"],"URL":"https:\/\/doi.org\/10.1017\/s0022149x00033691","relation":{},"ISSN":["0022-149X","1475-2697"],"issn-type":[{"value":"0022-149X","type":"print"},{"value":"1475-2697","type":"electronic"}],"subject":[],"published":{"date-parts":[[1964,6]]}}}