{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:46:16Z","timestamp":1792640776600,"version":"4.5.0"},"reference-count":7,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,11,18]],"date-time":"2009-11-18T00:00:00Z","timestamp":1258502400000},"content-version":"unspecified","delay-in-days":10124,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[1982,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Infection of a dog with <jats:italic>Strongyloides stercoralis<\/jats:italic> filariform larvae resulted in a persistent infection. Patent infections were not seen in rabbits, guinea-pigs, rats and 11 inbred strains and one outbred strain of mice. Manipulation of factors known to influence <jats:italic>S. ratti<\/jats:italic> infections in mice, such as age and sex of the host and the route of larval presentation, did not facilitate the appearance of rhabditiform larvae in the stools. Administration of immunosuppressive doses of corticosterioids to rabbits, guinea-pigs and C57B1\/6 mice did not permit complete development. Similarly, the course of infection was not altered in T cell-deficient hypothymic (nu\/nu) mice. The fate of filariform larvae applied to the skin of mice was ascertained; filariform larvae were observed to migrate from the skin via the lungs to the muscles within several days of infection. Although <jats:italic>S. stercoralis<\/jats:italic> does not develop to maturity in the small intestine of mice, this system does allow <jats:italic>in vivo<\/jats:italic> studies of the actions of anthelmintics against filariform larvae as well as a number of aspects of the immune response to this parasite.<\/jats:p>","DOI":"10.1017\/s0022149x00034957","type":"journal-article","created":{"date-parts":[[2009,11,18]],"date-time":"2009-11-18T15:55:55Z","timestamp":1258559755000},"page":"23-26","source":"Crossref","is-referenced-by-count":34,"title":["Attempts to establish infections with <i>Strongyloides stercoralis<\/i> in mice and other laboratory animals"],"prefix":"10.1017","volume":"56","author":[{"given":"H. J. S.","family":"Dawkins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. I.","family":"Grove","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2009,11,18]]},"reference":[{"key":"S0022149X00034957_ref006","doi-asserted-by":"publisher","DOI":"10.2307\/3280297"},{"key":"S0022149X00034957_ref004","unstructured":"Grove D. I. & Dawkins H. J. S. (in press) Effects of prednisolone on murine strongyloidiasis. Parasitology."},{"key":"S0022149X00034957_ref001","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(80)90023-5"},{"key":"S0022149X00034957_ref002","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(81)90031-X"},{"key":"S0022149X00034957_ref005","doi-asserted-by":"publisher","DOI":"10.2307\/3277855"},{"key":"S0022149X00034957_ref003","first-page":"1","article-title":"Uber das verhalten der larven von Strongyloides stercoralis, hakenwurmern und Ascaris lumbricoides im koper des wirtes","volume":"31","author":"F\u016dlleborn","year":"1927","journal-title":"Archiv fur Schiffs- und Tropenhygiene"},{"key":"S0022149X00034957_ref007","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-308X(08)60575-8"}],"container-title":["Journal of Helminthology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022149X00034957","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T17:40:59Z","timestamp":1558719659000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022149X00034957\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,3]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1982,3]]}},"alternative-id":["S0022149X00034957"],"URL":"https:\/\/doi.org\/10.1017\/s0022149x00034957","relation":{},"ISSN":["0022-149X","1475-2697"],"issn-type":[{"value":"0022-149X","type":"print"},{"value":"1475-2697","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,3]]}}}