{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T16:03:40Z","timestamp":1783958620100,"version":"3.55.0"},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In Thailand, infection with the liver fluke <jats:italic>Opisthorchis viverrini<\/jats:italic> is a serious health problem, with over 8.6 million human infections each year. Early stage biliary intrahepatic migration and infection of <jats:italic>O. viverrini<\/jats:italic> in the Syrian golden hamster were used to study the growth and development of this fluke. Fifty metacercariae of <jats:italic>O. viverrini<\/jats:italic> were introduced into each hamster by gastric intubation. Worms were found to migrate rapidly from the stomach to the gall bladder and hepatic duct, where they remained in relatively constant numbers until the end of week 8. Sexual development of worms was rapid, with full development of the uterus and testes by one and one half weeks and the appearance of eggs in the uterus by the beginning of the third week of infection. Worm growth as indicated by body length had ceased by week 8. Hamsters demonstrated development of a full reproductive cycle with in three to four weeks, and this generation continued until 8 weeks.<\/jats:p>","DOI":"10.1017\/s0022149x07212106","type":"journal-article","created":{"date-parts":[[2008,3,31]],"date-time":"2008-03-31T06:17:41Z","timestamp":1206944261000},"page":"39-41","source":"Crossref","is-referenced-by-count":13,"title":["Early stage biliary and intrahepatic migration of <i>Opisthorchis viverrini<\/i> in the golden hamster"],"prefix":"10.1017","volume":"81","author":[{"given":"C.","family":"Nithikathkul","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Tesana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Sithithaworn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Balakanich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2007,3,1]]},"reference":[{"key":"S0022149X07212106_ref7","first-page":"81","article-title":"Studies on Opisthorchis viverrini in Thailand","volume":"62","author":"Sadun","year":"1955","journal-title":"American Journal of Hygiene."},{"key":"S0022149X07212106_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(91)90449-9"},{"key":"S0022149X07212106_ref6","first-page":"49","article-title":"Opisthorchiasis","volume":"9","author":"Nithikathkul","year":"2002","journal-title":"Association of Private Higher Education Institutions of Thailand Journal"},{"key":"S0022149X07212106_ref3","doi-asserted-by":"publisher","DOI":"10.3347\/kjp.1993.31.2.83"},{"key":"S0022149X07212106_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(93)90046-2"},{"key":"S0022149X07212106_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(83)90132-3"},{"key":"S0022149X07212106_ref10","first-page":"535","volume-title":"in Marcel-Rojas, P.A. (Ed.) Pathology of protozoal and helminthic diseases with clinical correlation. Baltimore, Williams and Wilkins","author":"Tansurat","year":"1971"},{"key":"S0022149X07212106_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-308X(08)60448-0"},{"key":"S0022149X07212106_ref5","first-page":"274","article-title":"Liver fluke","volume":"26","author":"Nithikathkul","year":"2000","journal-title":"Journal of Communicable Diseases"},{"key":"S0022149X07212106_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(00)00054-0"},{"key":"S0022149X07212106_ref11","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1985.34.903"}],"container-title":["Journal of Helminthology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022149X07212106","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T15:28:45Z","timestamp":1554737325000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022149X07212106\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["S0022149X07212106"],"URL":"https:\/\/doi.org\/10.1017\/s0022149x07212106","relation":{},"ISSN":["0022-149X","1475-2697"],"issn-type":[{"value":"0022-149X","type":"print"},{"value":"1475-2697","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,3]]}}}