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Helminthol."],"published-print":{"date-parts":[[2009,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Every month during the year 2006\u20132007, the 24, 48, 72 and 96\u00a0h LC<jats:sub>50<\/jats:sub>values of a molluscicide, cypermethrin, were determined for a snail<jats:italic>Lymnaea acuminata<\/jats:italic>, with concomitant estimation of levels of temperature, pH, dissolved oxygen and carbon dioxide and electrical conductivity, both in control and test water. On the basis of a 24\u00a0h toxicity assay, it was noted that LC<jats:sub>50<\/jats:sub>values of 10.39, 10.90 and 11.19\u00a0mg\u00a0l<jats:sup>\u2212\u00a01<\/jats:sup>during the months of May, June and July, respectively, were most effective in killing the snails, while the molluscicide was least effective in the month of January, when its 24\u00a0h LC<jats:sub>50<\/jats:sub>was 65.84\u00a0mg\u00a0l<jats:sup>\u2212\u00a01<\/jats:sup>.There was a significant positive correlation between LC<jats:sub>50<\/jats:sub>of cypermethrin and levels of dissolved O<jats:sub>2<\/jats:sub>\/pH of water in corresponding months. On the contrary, a negative correlation was observed between LC<jats:sub>50<\/jats:sub>and dissolved CO<jats:sub>2<\/jats:sub>\/temperature of test water in the same months. In order to ascertain that such a relationship between toxicity and abiotic factors is not coincidental, the nervous tissue of the snail was assayed for the activity of acetylcholinesterase (AChE), acid phosphatase (ACP) and alkaline phosphatase (ALP) to sublethal concentrations (40% and 80%) of 24\u00a0h LC<jats:sub>50<\/jats:sub>during each of the 12 months of the same year. The findings confirmed that abiotic factors indeed influence toxicity of cypermethrin in the snail. A significant positive rank correlation between AChE, ACP and ALP activity did exist following exposure to the corresponding sublethal concentrations. Moreover, there was a maximum inhibition of 61.29 and 76.16% of AChE and ACP, respectively, in snails exposed to 80% of the 24\u00a0h LC<jats:sub>50<\/jats:sub>in the month of May. A similar treatment caused a maximum inhibition of 70.53% of ALP activity in the month of June. This work shows conclusively that the best time to control the snail population with cypermethrin is during the months of May and June.<\/jats:p>","DOI":"10.1017\/s0022149x08086252","type":"journal-article","created":{"date-parts":[[2008,10,16]],"date-time":"2008-10-16T08:42:55Z","timestamp":1224146575000},"page":"39-45","source":"Crossref","is-referenced-by-count":18,"title":["The effect of abiotic factors on the toxicity of cypermethrin against the snail<i>Lymnaea acuminata<\/i>in the control of fascioliasis"],"prefix":"10.1017","volume":"83","author":[{"given":"V.","family":"Singh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.K.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,3,1]]},"reference":[{"key":"S0022149X08086252_ref36","unstructured":"Watten B.J. 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