{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T14:02:51Z","timestamp":1785765771443,"version":"3.56.0"},"reference-count":38,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2010,11,10]],"date-time":"2010-11-10T00:00:00Z","timestamp":1289347200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This paper provides an estimation of the point prevalence of fascioliasis and its economic impact in terms of increased milk yield after chemotherapy of a bovine population from the district of Toba Tek Singh, Punjab, Pakistan. A total of 2400 cattle and buffaloes were examined quantitatively using the McMaster egg-counting technique. Infected cattle and buffaloes (50 of each) were randomly selected and each divided into two groups of 25 animals. Groups A (buffaloes) and C (cattle) were treated with oxyclozanide (orally, 16.6\u00a0mg\u00a0kg<jats:sup>\u2212\u00a01<\/jats:sup>body weight). Groups B and D served as negative controls for buffaloes and cattle, respectively. Pre- and post-treatment milk yield was recorded to determine if there were any changes in milk yield after treatment. Of 2400 faecal samples analysed, 654 (27.25%) were positive for<jats:italic>Fasciola<\/jats:italic>spp. with a mean number of eggs per gram (EPG) of 503.2. The point prevalence and worm burden of fascioliasis was significantly higher (OR\u00a0=\u00a02.13;<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05) in buffaloes (34.58%; 415\/1200; mean EPG maximum likelihood\u00a0=\u00a0521.4) as compared to that of cattle (19.92%; 239\/1200; mean EPG maximum likelihood\u00a0=\u00a0415.8). Among the parasite species,<jats:italic>F. gigantica<\/jats:italic>(19.88%; 477\/2400) was predominant (OR\u00a0=\u00a03.12;<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05) as compared to<jats:italic>F. hepatica<\/jats:italic>(7.38%; 177\/2400). An average daily increase of 0.67 and 0.87 litres of milk, with 0.41% and 0.37% more fat per animal, was observed in oxyclozanide-treated buffaloes and cattle, respectively. The economic value of reduced production of infected animals was estimated as US$0.33 and 0.32 per animal per day for cattle and buffaloes, respectively.<\/jats:p>","DOI":"10.1017\/s0022149x10000659","type":"journal-article","created":{"date-parts":[[2010,11,10]],"date-time":"2010-11-10T11:23:12Z","timestamp":1289388192000},"page":"334-338","source":"Crossref","is-referenced-by-count":10,"title":["Point prevalence of bovine fascioliasis and the influence of chemotherapy on the milk yield in a lactating bovine population from the district of Toba Tek Singh, Pakistan"],"prefix":"10.1017","volume":"85","author":[{"given":"M.K.","family":"Khan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.S.","family":"Sajid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.N.","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Iqbal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Arshad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Hussain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2010,11,10]]},"reference":[{"key":"S0022149X10000659_ref38","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4017(95)00806-2"},{"key":"S0022149X10000659_ref37","doi-asserted-by":"publisher","DOI":"10.1136\/vr.98.1.5"},{"key":"S0022149X10000659_ref35","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2004.12.009"},{"key":"S0022149X10000659_ref36","first-page":"180","volume-title":"Veterinary epidemiology","author":"Thrusfield","year":"2008"},{"key":"S0022149X10000659_ref34","first-page":"465","volume-title":"Fasciolosis","author":"Spithill","year":"1999"},{"key":"S0022149X10000659_ref32","doi-asserted-by":"publisher","DOI":"10.1136\/vr.157.7.188"},{"key":"S0022149X10000659_ref30","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1996.54.146"},{"key":"S0022149X10000659_ref29","unstructured":"Sahar R. 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