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The zoonotic role of this parasite had already been suspected in Europe as the clinical signs and histopathology seen in two ocular cases from Albania and the Crimean region were very similar to those of canine ocular onchocerciasis. In the most recent reports of human onchocerciasis,<jats:italic>O. lupi<\/jats:italic>has been morphologically and molecularly identified as the causative agent of ocular infestation in two patients from Turkey, and one patient from Tunisia. Here, we report an additional case of nodular lesions involving two, and possibly more, immature worms in a patient from Iran. The parasite was found to belong to the genus<jats:italic>Onchocerca<\/jats:italic>based on morphological features and the species was confirmed as<jats:italic>O. lupi<\/jats:italic>from a partial sequence analysis of 12S ribosomal DNA.<\/jats:p>","DOI":"10.1017\/s0022149x13000060","type":"journal-article","created":{"date-parts":[[2013,2,6]],"date-time":"2013-02-06T15:33:06Z","timestamp":1360164786000},"page":"250-255","source":"Crossref","is-referenced-by-count":43,"title":["Human ocular onchocerciasis caused by<i>Onchocerca lupi<\/i>(Spirurida, Onchocercidae) in Iran"],"prefix":"10.1017","volume":"88","author":[{"given":"G.","family":"Mowlavi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Farzbod","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Kheirkhah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Mobedi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.D.","family":"Bowman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.R.","family":"Naddaf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2013,2,7]]},"reference":[{"key":"S0022149X13000060_ref45","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200204000-00020"},{"key":"S0022149X13000060_ref43","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2915.2012.01023.x"},{"key":"S0022149X13000060_ref42","doi-asserted-by":"publisher","DOI":"10.1016\/j.parint.2004.08.003"},{"key":"S0022149X13000060_ref41","doi-asserted-by":"publisher","DOI":"10.1051\/parasite\/2004113285"},{"key":"S0022149X13000060_ref39","doi-asserted-by":"publisher","DOI":"10.1051\/parasite\/1996032179"},{"key":"S0022149X13000060_ref36","doi-asserted-by":"publisher","DOI":"10.1179\/000349802125001267"},{"key":"S0022149X13000060_ref35","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2007.09.008"},{"key":"S0022149X13000060_ref32","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2001.65.108"},{"key":"S0022149X13000060_ref30","first-page":"73","article-title":"Epidemiological 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