{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T06:55:11Z","timestamp":1776408911797,"version":"3.51.2"},"reference-count":40,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2018,3,5]],"date-time":"2018-03-05T00:00:00Z","timestamp":1520208000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Ascaris<\/jats:italic>sp. is a soil-transmitted helminth (STH) significantly affecting the health of human and swine populations. Health inequities and poverty, with resulting deficiencies in water, sanitation and hygiene, are directly associated with<jats:italic>Ascaris lumbricoides<\/jats:italic>prevalence in humans. Resource constraints also lead to small-scale livestock production under unsanitary conditions. Free-ranging pigs, for instance, are exposed to a number of infectious agents, among which<jats:italic>Ascaris suum<\/jats:italic>is one of the most common. Under these conditions, close proximity between people and pigs can result in cross-contamination; that is, pigs harbouring human<jats:italic>Ascaris<\/jats:italic>and vice versa. Moreover, the potential interbreeding between these two<jats:italic>Ascaris<\/jats:italic>species has been demonstrated. The present study analysed<jats:italic>Ascaris<\/jats:italic>worms obtained from children and pigs in Honduras. Adult worms were collected from stool samples of children after pharmacological treatment, and from pigs\u2019 intestines after slaughter for commercial purposes at a local abattoir. A nuclear ribosomal internal transcribed spacer (ITS) region was amplified by polymerase chain reaction (PCR) and digested with a restriction enzyme in order to separate putative human- and pig-derived<jats:italic>Ascaris<\/jats:italic>isolates. PCR products were also sequenced, and cladograms were constructed. All parasites isolated from children showed the typical human-derived genotype of<jats:italic>Ascaris<\/jats:italic>, whereas 91% of parasites from pigs showed the expected pig-derived genotype. Cross-infections between hosts were not demonstrated in this study. Nine per cent of pig-derived worms showed a restriction band pattern highly suggestive of a hybrid human\u2013pig<jats:italic>Ascaris<\/jats:italic>genotype. These results contribute to the understanding of ascariasis epidemiology and its zoonotic potential in a highly endemic region.<\/jats:p>","DOI":"10.1017\/s0022149x18000160","type":"journal-article","created":{"date-parts":[[2018,3,5]],"date-time":"2018-03-05T07:48:26Z","timestamp":1520236106000},"page":"154-158","source":"Crossref","is-referenced-by-count":16,"title":["Molecular analysis of human- and pig-derived<i>Ascaris<\/i>in 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