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Thus, the aim of this study was to evaluate the effect of the<jats:italic>Saccharomyces boulardii<\/jats:italic>probiotic on the vertical transmission of<jats:italic>T<\/jats:italic>.<jats:italic>canis<\/jats:italic>in Swiss mice. The mice received 10<jats:sup>7<\/jats:sup><jats:italic>S<\/jats:italic>.<jats:italic>boulardii<\/jats:italic>colony-forming units per gram of food. The supplementation began 15 days before mating and was maintained throughout pregnancy and lactation. The animals were inoculated with 300<jats:italic>T<\/jats:italic>.<jats:italic>canis<\/jats:italic>embryonated eggs on the 14th day of pregnancy. The presence of larvae was examined in the organs of the females and their offspring. The examined organs included the following: brain, liver, lungs, heart, kidneys, spleen, eye, skeletal muscle (carcass) and mammary glands of lactating females. There was a 42% (<jats:italic>P<\/jats:italic>= 0.041) reduction in the number of larvae transmitted to offspring in the group that received probiotic-supplemented food (GI). Additionally, there was a 50% reduction (<jats:italic>P<\/jats:italic>= 0.023) in the number of larvae found in the brains of lactating offspring in the GI group. These results reveal the potential of<jats:italic>S<\/jats:italic>.<jats:italic>boulardii<\/jats:italic>probiotic use as an auxiliary method of controlling visceral toxocariasis.<\/jats:p>","DOI":"10.1017\/s0022149x20001030","type":"journal-article","created":{"date-parts":[[2021,3,2]],"date-time":"2021-03-02T10:11:31Z","timestamp":1614679891000},"source":"Crossref","is-referenced-by-count":4,"title":["<i>Saccharomyces boulardii<\/i>reduces the vertical transmission of<i>Toxocara canis<\/i>larvae in mice"],"prefix":"10.1017","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8988-6335","authenticated-orcid":false,"given":"L.A.X.","family":"Cruz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5220-0229","authenticated-orcid":false,"given":"C.D.","family":"Hirsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2900-8300","authenticated-orcid":false,"given":"M.Q.","family":"de Moura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2171-7046","authenticated-orcid":false,"given":"L.F.C.","family":"de Avila","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5762-0217","authenticated-orcid":false,"given":"L.H.R.","family":"Martins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1397-4926","authenticated-orcid":false,"given":"G.B.","family":"Klafke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1072-4374","authenticated-orcid":false,"given":"F.R.","family":"Concei\u00e7\u00e3o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4444-1134","authenticated-orcid":false,"given":"M.E.A.","family":"Berne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7998-0256","authenticated-orcid":false,"given":"C.J.","family":"Scaini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,3,2]]},"reference":[{"key":"S0022149X20001030_ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-019-06567-5"},{"key":"S0022149X20001030_ref19","doi-asserted-by":"publisher","DOI":"10.4061\/2010\/823710"},{"key":"S0022149X20001030_ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-013-3376-5"},{"key":"S0022149X20001030_ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.parint.2008.06.006"},{"key":"S0022149X20001030_ref26","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.112.039644"},{"key":"S0022149X20001030_ref24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2010.00836.x"},{"key":"S0022149X20001030_ref30","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001775"},{"key":"S0022149X20001030_ref20","doi-asserted-by":"publisher","DOI":"10.2307\/3279158"},{"key":"S0022149X20001030_ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2013.07.004"},{"key":"S0022149X20001030_ref17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000400"},{"key":"S0022149X20001030_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(83)80017-4"},{"key":"S0022149X20001030_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.medmal.2013.10.002"},{"key":"S0022149X20001030_ref7","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1542\/peds.9.1.7","article-title":"Chronic eosinophilia due to visceral larva migrans; 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