{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T13:38:18Z","timestamp":1794231498305,"version":"4.9.0"},"reference-count":28,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T00:00:00Z","timestamp":1734652800000},"content-version":"unspecified","delay-in-days":354,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:p>Previous studies have shown that helminth infection protects against the development of diabetes mellitus (DM), possibly related to the hygiene hypothesis. However, studies involving <jats:italic>Stronglyoides stercoralis<\/jats:italic> and its possible association with DM are scarce and have shown contradicting results, prompting us to perform this meta-analysis to obtain more precise estimates. Related studies were searched from PubMed, Google Scholar, Science Direct, and Cochrane Library until 1 August 2024. Data on the occurrence of DM in patients positive and negative for <jats:italic>S. stercoralis<\/jats:italic> were obtained. All analyses were done using Review Manager 5.4. The initial search yielded a total of 1725 studies, and after thorough screening and exclusion, only five articles involving 2106 participants (536 cases and 1570 controls) were included in the meta-analysis. Heterogeneity was assessed, and outlier studies were excluded using a funnel plot. Results showed a significant association of <jats:italic>S. stercoralis<\/jats:italic> infection with DM, suggesting that those with the infection are less likely to develop DM. Overall, the results suggest that <jats:italic>S. stercoralis<\/jats:italic> infection may decrease the likelihood of developing DM, potentially supporting the hygiene hypothesis.<\/jats:p>","DOI":"10.1017\/s0022149x24000828","type":"journal-article","created":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T07:51:52Z","timestamp":1734681112000},"source":"Crossref","is-referenced-by-count":1,"title":["Association of <i>Strongyloides stercoralis<\/i> infection with the development of diabetes mellitus: a meta-analysis"],"prefix":"10.1017","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7793-6558","authenticated-orcid":false,"given":"R.E.","family":"Tiongco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.A.","family":"Flores","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.J.","family":"Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.A.","family":"Dayrit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.J.","family":"Dominguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Manahan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.R.","family":"Pineda-Cortel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2024,12,20]]},"reference":[{"key":"S0022149X24000828_r8","doi-asserted-by":"publisher","DOI":"10.1111\/1753-0407.13250"},{"key":"S0022149X24000828_r12","doi-asserted-by":"publisher","DOI":"10.1186\/s40249-018-0488-2"},{"key":"S0022149X24000828_r25","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19042084"},{"key":"S0022149X24000828_r24","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.16-0348"},{"key":"S0022149X24000828_r18","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2018.04.008"},{"key":"S0022149X24000828_r28","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0269080"},{"key":"S0022149X24000828_r3","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000001596"},{"key":"S0022149X24000828_r4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2015.01.003"},{"key":"S0022149X24000828_r11","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1186"},{"key":"S0022149X24000828_r7","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofw029"},{"key":"S0022149X24000828_r26","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-31118-5"},{"key":"S0022149X24000828_r27","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/7297419"},{"key":"S0022149X24000828_r16","doi-asserted-by":"publisher","DOI":"10.1093\/trstmh\/try132"},{"key":"S0022149X24000828_r1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-36112-5"},{"key":"S0022149X24000828_r19","unstructured":"Pineda, 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