{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:27:51Z","timestamp":1790011671885,"version":"4.0.1"},"reference-count":59,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T00:00:00Z","timestamp":1757462400000},"content-version":"unspecified","delay-in-days":252,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Strongyloidiasis, caused by\n                    <jats:italic>Strongyloides stercoralis<\/jats:italic>\n                    , is a neglected parasitic disease and a major global public health issue. This infection exhibits diverse clinical manifestations that, along with the high rates of asymptomatic cases and low-sensitivity diagnostic methods, contribute to the underreporting of the disease. With an estimated 600 million people infected worldwide, this disease is particularly prevalent in tropical and subtropical regions with poor sanitary conditions, which includes Brazil. Understanding the epidemiology of the disease is essential for the development of control strategies, but the lack of comprehensive data makes it difficult to identify the real impact of the infection, thus leading to underreporting and a lack of awareness of its severity on public health. Given this scenario, this literature review aimed to summarize the reported prevalence and associated factors of strongyloidiasis in Brazil. A total of 33 articles published between 2005 and 2025 were retrieved from PubMed, Science Direct, Scielo, and LiLacs databases using keywords related to strongyloidiasis in Brazil. The data collected in this review indicate that the majority of the published studies are concentrated in the Southeast region of Brazil, with the state of Minas Gerais accounting for the highest number of publications. It was also observed that the prevalence of strongyloidiasis is underestimated due to diagnostic challenges and high rates of false negatives, especially among asymptomatic patients. In addition, the scarcity of specific studies on the disease in Brazil limits the understanding of its true incidence, underscoring the need for further research.\n                  <\/jats:p>","DOI":"10.1017\/s0022149x25100722","type":"journal-article","created":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T12:15:06Z","timestamp":1757506506000},"source":"Crossref","is-referenced-by-count":1,"title":["A general and epidemiological overview of strongyloidiasis in Brazil"],"prefix":"10.1017","volume":"99","author":[{"given":"Y.M.","family":"dos Santos-Destro","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01585b035","id-type":"ROR","asserted-by":"publisher"}],"name":"State University of Londrina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.P.","family":"Nunes","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01585b035","id-type":"ROR","asserted-by":"publisher"}],"name":"State University of Londrina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.M.","family":"Suzuki","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01585b035","id-type":"ROR","asserted-by":"publisher"}],"name":"State University of Londrina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.M.","family":"Souza Cruz","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01585b035","id-type":"ROR","asserted-by":"publisher"}],"name":"State University of Londrina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.C.J.","family":"Rodrigues","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01585b035","id-type":"ROR","asserted-by":"publisher"}],"name":"State University of Londrina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.B.","family":"Detoni","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01585b035","id-type":"ROR","asserted-by":"publisher"}],"name":"State University of Londrina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.B.B.","family":"Tonzar","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01585b035","id-type":"ROR","asserted-by":"publisher"}],"name":"State University of Londrina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3697-9711","authenticated-orcid":false,"given":"I.N.","family":"Costa","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01585b035","id-type":"ROR","asserted-by":"publisher"}],"name":"State University of Londrina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,9,10]]},"reference":[{"key":"S0022149X25100722_r14","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-04243-3"},{"key":"S0022149X25100722_r30","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46652013000500003"},{"key":"S0022149X25100722_r2","first-page":"115","article-title":"Enteric parasitic infections in HIV\/AIDS patients before and after the highly active antiretroviral therapy","volume":"12","author":"Bachur","year":"2008","journal-title":"Brazilian Journal of Infectious Diseases"},{"key":"S0022149X25100722_r5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2011.02816.x"},{"key":"S0022149X25100722_r44","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2008.05700.x"},{"key":"S0022149X25100722_r1","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1590\/S0102-311X2013000800006","article-title":"Preval\u00eancia de parasitos intestinais na comunidade ind\u00edgena Maxakali, Minas Gerais, Brasil, 2009","volume":"29","author":"Assis","year":"2013","journal-title":"Cadernos de Sa\u00fade P\u00fablica"},{"key":"S0022149X25100722_r33","doi-asserted-by":"publisher","DOI":"10.3390\/tropicalmed3020053"},{"key":"S0022149X25100722_r11","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2022.0442"},{"key":"S0022149X25100722_r9","doi-asserted-by":"publisher","DOI":"10.1590\/0037-8682-0019-2015"},{"key":"S0022149X25100722_r37","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0011283"},{"key":"S0022149X25100722_r54","doi-asserted-by":"publisher","DOI":"10.5216\/rpt.v44i4.39240"},{"key":"S0022149X25100722_r49","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2024.07.010"},{"key":"S0022149X25100722_r3","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0193860"},{"key":"S0022149X25100722_r27","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000717"},{"key":"S0022149X25100722_r62","doi-asserted-by":"publisher","DOI":"10.17765\/2176-9206.2019v12n3p495-502"},{"key":"S0022149X25100722_r32","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2019.105279"},{"key":"S0022149X25100722_r21","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2023.115927"},{"key":"S0022149X25100722_r4","first-page":"e13","article-title":"Opportunistic and non-opportunistic intestinal parasites in HIV\/AIDS patients in relation to their clinical and epidemiological status in a specialized medical service in Goi\u00e1s","volume":"60","author":"Barcelos","year":"2018","journal-title":"Brazil. Revista do Instituto de Medicina Tropical de S\u00e3o Paulo"},{"key":"S0022149X25100722_r45","volume-title":"Guideline: Preventive Chemotherapy to Control Soil-Transmitted Helminth Infections in At-Risk Population Groups","year":"2017"},{"key":"S0022149X25100722_r8","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens9060468"},{"key":"S0022149X25100722_r38","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002288"},{"key":"S0022149X25100722_r15","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0005445"},{"key":"S0022149X25100722_r28","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0007998"},{"key":"S0022149X25100722_r50","first-page":"e46908","article-title":"Strongyloides stercoralis infection in humans: a narrative review of the most neglected parasitic disease","volume":"15","author":"Yeh","year":"2023","journal-title":"Cureus"},{"key":"S0022149X25100722_r13","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-022-00528-z"},{"key":"S0022149X25100722_r55","doi-asserted-by":"publisher","DOI":"10.1111\/pim.13059"},{"key":"S0022149X25100722_r101","doi-asserted-by":"publisher","DOI":"10.7705\/biomedica.5888"},{"key":"S0022149X25100722_r64","doi-asserted-by":"publisher","DOI":"10.5216\/rpt.v46i1.46301"},{"key":"S0022149X25100722_r20","doi-asserted-by":"publisher","DOI":"10.1590\/0037-8682-981-2013"},{"key":"S0022149X25100722_r65","doi-asserted-by":"publisher","DOI":"10.15446\/rsap.v16n6.40031"},{"key":"S0022149X25100722_r6","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2015.07.026"},{"key":"S0022149X25100722_r22","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-023-00490-x"},{"key":"S0022149X25100722_r16","doi-asserted-by":"publisher","DOI":"10.1590\/0001-3765202320230323"},{"key":"S0022149X25100722_r43","doi-asserted-by":"publisher","DOI":"10.1007\/s12639-019-01090-x"},{"key":"S0022149X25100722_r39","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2015.11.010"},{"key":"S0022149X25100722_r52","doi-asserted-by":"publisher","DOI":"10.1111\/pim.12793"},{"key":"S0022149X25100722_r63","doi-asserted-by":"publisher","DOI":"10.14393\/BJ-v34n1a2018-39899"},{"key":"S0022149X25100722_r10","volume-title":"Plano nacional de vigil\u00e2ncia e controle das enteroparasitoses","author":"Carmo","year":"2005"},{"key":"S0022149X25100722_r66","doi-asserted-by":"publisher","DOI":"10.1590\/0037-8682-0090-2018"},{"key":"S0022149X25100722_r57","doi-asserted-by":"crossref","first-page":"e14153","DOI":"10.1111\/tid.14153","article-title":"Strongyloides infection screening in transplant candidates: What is the best strategy?","volume":"25","author":"Gryschek","year":"2023","journal-title":"Transplant Infectious Disease"},{"key":"S0022149X25100722_r56","unstructured":"Government of Brazil (GOV) (2025) Ministry of Health (Brazil). Ordinance GM\/MS No. 6,734 of March 18, 2025. Official Gazette of the Union [Internet]. 2025 Mar 31 [cited on (20 April 2025)]. Available at https:\/\/www.in.gov.br\/en\/web\/dou\/-\/portaria-gm-ms-n-6.734-de-18-de-marco-de-2025-620767223."},{"key":"S0022149X25100722_r58","first-page":"802","article-title":"Prevalence and transmission of intestinal parasitosis in human beings from Zona da Mata","volume":"34","author":"Iasbik","year":"2018","journal-title":"Minas Gerais, Brazil. Journal of Biosciences"},{"key":"S0022149X25100722_r51","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2019.105305"},{"key":"S0022149X25100722_r40","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-022-07736-9"},{"key":"S0022149X25100722_r59","doi-asserted-by":"publisher","DOI":"10.1590\/1519-6984.175364"},{"key":"S0022149X25100722_r61","doi-asserted-by":"publisher","DOI":"10.1590\/S0037-86822008000600007"},{"key":"S0022149X25100722_r60","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.17.1.208-217.2004"},{"key":"S0022149X25100722_r18","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-022-05284-w"},{"key":"S0022149X25100722_r12","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2021.106081"},{"key":"S0022149X25100722_r25","doi-asserted-by":"publisher","DOI":"10.3390\/tropicalmed7100310"},{"key":"S0022149X25100722_r47","volume-title":"Diagnostic Methods for the Control of Strongyloidiasis: Virtual Meeting, 29 September 2020","year":"2020b"},{"key":"S0022149X25100722_r23","first-page":"100619","article-title":"Potentially zoonotic parasites in the soil of public squares in the city of Aracaju (Sergipe, Northeastern Brazil)","volume":"26","author":"Lee","year":"2021","journal-title":"Veterinary Parasitology: Regional Studies and Reports"},{"key":"S0022149X25100722_r36","first-page":"1","article-title":"O diagn\u00f3stico laboratorial e o acompanhamento da estrongiloid\u00edase: uma revis\u00e3o sistem\u00e1tica","volume":"7","author":"Requena-M\u00e9ndez","year":"2013","journal-title":"PLoS Neglected Tropical Diseases"},{"key":"S0022149X25100722_r42","doi-asserted-by":"publisher","DOI":"10.1179\/1364859411Y.0000000034"},{"key":"S0022149X25100722_r29","doi-asserted-by":"publisher","DOI":"10.1590\/S0037-86822008000600004"},{"key":"S0022149X25100722_r34","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12909"},{"key":"S0022149X25100722_r67","doi-asserted-by":"publisher","DOI":"10.7705\/biomedica.5888"},{"key":"S0022149X25100722_r48","unstructured":"World Health Organization (2023) Strongyloidiasis. Control of Neglected Tropical Diseases. Available at https:\/\/www.who.int\/teams\/control-of-neglected-tropical-diseases\/soil-transmitted-helminthiases\/strongyloidiasis (accessed 5 July 2024)."},{"key":"S0022149X25100722_r46","volume-title":"Ending the Neglect to Attain the Sustainable Development Goals: A Road Map for Neglected Tropical Diseases 2021\u20132030","year":"2020a"}],"container-title":["Journal of Helminthology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022149X25100722","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T12:15:10Z","timestamp":1757506510000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022149X25100722\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":59,"alternative-id":["S0022149X25100722"],"URL":"https:\/\/doi.org\/10.1017\/s0022149x25100722","relation":{},"ISSN":["0022-149X","1475-2697"],"issn-type":[{"value":"0022-149X","type":"print"},{"value":"1475-2697","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"e105"}}