{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:23:10Z","timestamp":1785424990344,"version":"3.56.0"},"reference-count":29,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"unspecified","delay-in-days":182,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The study of hyperinfection in animal models is important to control strongyloidiasis as a public health concern. While human strongyloidiasis is often chronic, experimental models allow the assessment of the acute phase of hyperinfection. This study evaluated excretory\/secretory (E\/S) antigens of\n                    <jats:italic>Strongyloides venezuelensis<\/jats:italic>\n                    L3 larvae to detect IgG antibodies in serum samples from rats immunosuppressed or not and experimentally infected or not with\n                    <jats:italic>S. venezuelensis.<\/jats:italic>\n                    Infection parameters and IgG detection by the antigenic extracts \u2013 total saline extract (TS), E\/S in RPMI 1640 (RPMI E\/S), and E\/S in phosphate buffered saline (PBS E\/S) \u2013 were evaluated. RPMI E\/S achieved the best diagnostic parameters, showing no reactivity with non-infected controls. These data demonstrate that E\/S antigens are effective for detecting strongyloidiasis during the acute hyperinfection window, offering a reliable tool for experimental research and potential translational applications for screening high-risk patients.\n                  <\/jats:p>","DOI":"10.1017\/s0022149x26101692","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T06:37:16Z","timestamp":1782974236000},"source":"Crossref","is-referenced-by-count":0,"title":["Short communication: Excretory-secretory antigens allow effective IgG detection in experimental Strongyloides hyperinfection under immunosuppression"],"prefix":"10.1017","volume":"100","author":[{"given":"E.F.G.de","family":"Carvalho","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04x3wvr31","id-type":"ROR","asserted-by":"publisher"}],"name":"Federal University of Uberl\u00e2ndia: Universidade Federal de 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